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Author Details

Joshua W Knowles
1996
152
46
PMIDPaper TitleJournal TitlePublished Year
37034809<i>Single-cell transcriptome dataset of human and mouse</i> in vitro <i>adipogenesis models</i>.bioRxiv2023
36182570Chronic liver disease-related mortality in diabetes before and during the COVID-19 in the United States.Digestive and Liver Disease2023
37626170RNA interference targeting ANGPTL3 for triglyceride and cholesterol lowering: phase 1 basket trial cohorts.Nat Med2023
37961394Lac-Phe mediates the anti-obesity effect of metformin.bioRxiv2023
37328521Single-cell transcriptome dataset of human and mouse in vitro adipogenesis models.Sci Data2023
37119068Contemporary Homozygous Familial Hypercholesterolemia in the United States: Insights From the CASCADE FH Registry.J Am Heart Assoc2023
36619297The relationship between insulin resistance and ion mobility lipoprotein fractions.2023
37486064A single-cell CRISPRi platform for characterizing candidate genes relevant to metabolic disorders in human adipocytes.2023
35220969A guide for the diagnosis of rare and undiagnosed disease: beyond the exome.Genome Med2022
36094507Analysis of Insulin Resistance Among Children and Adolescents in Slovenia With Hypercholesterolemia After Treatment With Statins.JAMA network open2022
36206733Analysis of Transcriptional Variability in a Large Human iPSC Library Reveals Genetic and Non-genetic Determinants of Heterogeneity.Cell Stem Cell2022
35862071Creation of the American Heart Association Journals' Equity, Diversity, and Inclusion Editorial Board: The Next Step to Achieving the 2024 Impact Goal.Circulation2022
35413566Generation of two iPSC lines from hypertrophic cardiomyopathy patients carrying MYBPC3 and PRKAG2 variants.Stem Cell Research2022
36456565G protein-coupled receptor 151 regulates glucose metabolism and hepatic gluconeogenesis.Nature Communications2022
35293152Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD.Hepatol Commun2022
35292083Integration of genetic colocalizations with physiological and pharmacological perturbations identifies cardiometabolic disease genes.Genome Med2022
34906454The Clinical Genome Resource (ClinGen) Familial Hypercholesterolemia Variant Curation Expert Panel consensus guidelines for LDLR variant classification.Genet Med2022
35020984Ultrarapid Nanopore Genome Sequencing in a Critical Care Setting.N Engl J Med2022
35014955Online Patient Education Materials Related to Lipoprotein(a): Readability Assessment.Journal of Medical Internet Research2022
35143253Coronary Artery Disease Risk of Familial Hypercholesterolemia Genetic Variants Independent of Clinically Observed Longitudinal Cholesterol Exposure.Circ Genom Precis Med2022
34582792An integrated approach to identify environmental modulators of genetic risk factors for complex traits.Am J Hum Genet2021
34125567Diverse Racial/Ethnic Group Underreporting and Underrepresentation in High-Impact Cholesterol Treatment Trials.Circulation2021
33538426The need for polygenic score reporting standards in evidence-based practice: lipid genetics use case.Current Opinion in Lipidology2021
33743363Generation of two heterozygous MYBPC3 mutation-carrying human iPSC lines, SCVIi001-A and SCVIi002-A, for modeling hypertrophic cardiomyopathy.Stem Cell Research2021
33675770Validation of an Integrated Risk Tool, Including Polygenic Risk Score, for Atherosclerotic Cardiovascular Disease in Multiple Ethnicities and Ancestries.Am J Cardiol2021
34348115Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis.2021
34327498Health disparities in cardiometabolic risk among Black and Hispanic youth in the United States.Am J Prev Cardiol2021
34325839Genetics of Type 2 Diabetes: Opportunities for Precision Medicine: JACC Focus Seminar.Journal of the American College of Cardiology2021
32976895Children with Heterozygous Familial Hypercholesterolemia in the United States: Data from the Cascade Screening for Awareness and Detection-FH Registry.J Pediatr2021
34506305Signaling defects associated with insulin resistance in nondiabetic and diabetic individuals and modification by sex.J Clin Invest2021
34433298Statins Are Associated With Increased Insulin Resistance and Secretion.Arteriosclerosis, Thrombosis, and Vascular Biology2021
31220638Increasing Mortality Among Patients With Diabetes and Chronic Liver Disease From 2007 to 2017.Clinical Gastroenterology and Hepatology2020
32319337Gaps in Dyslipidemia Care Among Working-Aged Individuals With Employer-Sponsored Health Care.Journal of the American Heart Association2020
32193374FAM13A affects body fat distribution and adipocyte function.Nat Commun2020
32060542Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications.Endocrinology2020
31992297Association of insulin resistance, from mid-life to late-life, with aortic stiffness in late-life: the Atherosclerosis Risk in Communities Study.Cardiovasc Diabetol2020
31926863Cardiorespiratory Fitness, Body Mass Index, and Markers of Insulin Resistance in Apparently Healthy Women and Men.Am J Med2020
32208993Delisting : The Rise and Fall of a Putative Hypercholesterolemia Gene.Arteriosclerosis, Thrombosis, and Vascular Biology2020
32442913Genomic integrity of human induced pluripotent stem cells across nine studies in the NHLBI NextGen program.Stem Cell Res2020
32816232Women Living with Familial Hypercholesterolemia: Challenges and Considerations Surrounding Their Care.Curr Atheroscler Rep2020
33362275Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness.PLoS Comput Biol2020
31304370Finding missed cases of familial hypercholesterolemia in health systems using machine learning.NPJ Digit Med2019
31664995CRISPR-Cas9-mediated knockout of SPRY2 in human hepatocytes leads to increased glucose uptake and lipid droplet accumulation.BMC Endocr Disord2019
33323221Precision screening for familial hypercholesterolaemia: a machine learning study applied to electronic health encounter data.Lancet Digit Health2019
30595172Safety and Efficacy of PCSK9 Inhibitors After Heart Transplantation.Canadian Journal of Cardiology2019
30761309Genetic Testing and Risk Scores: Impact on Familial Hypercholesterolemia.Frontiers in Cardiovascular Medicine2019
30758506Association of Statin Adherence With Mortality in Patients With Atherosclerotic Cardiovascular Disease.JAMA Cardiol2019
30810766No evidence of a causal association of type 2 diabetes and glucose metabolism with atrial fibrillation.Diabetologia2019
31487564Longitudinal low density lipoprotein cholesterol goal achievement and cardiovascular outcomes among adult patients with familial hypercholesterolemia: The CASCADE FH registry.Atherosclerosis2019
31014093Impact of race/ethnicity on insulin resistance and hypertriglyceridaemia.Diab Vasc Dis Res2019
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