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Author Details

Dmitri V Rozanov
Oregon Health and Science University
1998
42
27
PMIDPaper TitleJournal TitlePublished Year
34146471A community challenge to evaluate RNA-seq, fusion detection, and isoform quantification methods for cancer discovery.Cell Syst2021
29331515MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection.J Proteomics2018
27307436Identification of shared TCR sequences from T cells in human breast cancer using emulsion RT-PCR.Proc Natl Acad Sci U S A2016
25849628A humanized leucine zipper-TRAIL hybrid induces apoptosis of tumors both in vitro and in vivo.PLoS One2015
26075913TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response.PLoS One2015
24771425Systemic effects of TRAIL (TNF-related apoptosis-inducing ligand) during acute γ-irradiation.Bull Exp Biol Med2014
21518756Dynamic interdomain interactions contribute to the inhibition of matrix metalloproteinases by tissue inhibitors of metalloproteinases.J Biol Chem2011
19551841Timp-2 binding with cellular MT1-MMP stimulates invasion-promoting MEK/ERK signaling in cancer cells.Int J Cancer2010
20605791Internal cleavages of the autoinhibitory prodomain are required for membrane type 1 matrix metalloproteinase activation, although furin cleavage alone generates inactive proteinase.J Biol Chem2010
19232058Biochemical evidence of the interactions of membrane type-1 matrix metalloproteinase (MT1-MMP) with adenine nucleotide translocator (ANT): potential implications linking proteolysis with energy metabolism in cancer cells.Biochem J2009
19509255Engineering a leucine zipper-TRAIL homotrimer with improved cytotoxicity in tumor cells.Mol Cancer Ther2009
17991754Tissue inhibitor of metalloproteinases-2 binding to membrane-type 1 matrix metalloproteinase induces MAPK activation and cell growth by a non-proteolytic mechanism.J Biol Chem2008
18519667Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer.Cancer Res2008
17761671Specific inhibition of autoimmune T cell transmigration contributes to beta cell functionality and insulin synthesis in non-obese diabetic (NOD) mice.J Biol Chem2007
16384550Both PA63 and PA83 are endocytosed within an anthrax protective antigen mixed heptamer: a putative mechanism to overcome a furin deficiency.Arch Biochem Biophys2006
17079467Membrane type-1 matrix metalloproteinase confers aneuploidy and tumorigenicity on mammary epithelial cells.Cancer Res2006
16778201Interference with the complement system by tumor cell membrane type-1 matrix metalloproteinase plays a significant role in promoting metastasis in mice.Cancer Res2006
16940151Mechanistic insights into targeting T cell membrane proteinase to promote islet beta-cell rejuvenation in type 1 diabetes.FASEB J2006
16510592Matrix metalloproteinase 26 proteolysis of the NH2-terminal domain of the estrogen receptor beta correlates with the survival of breast cancer patients.Cancer Res2006
16392787Anthrax lethal factor protease inhibitors: synthesis, SAR, and structure-based 3D QSAR studies.J Med Chem2006
16636666Furin regulates the intracellular activation and the uptake rate of cell surface-associated MT1-MMP.Oncogene2006
16627478O-glycosylation regulates autolysis of cellular membrane type-1 matrix metalloproteinase (MT1-MMP).J Biol Chem2006
16229682Cleavage targets and the D-arginine-based inhibitors of the West Nile virus NS3 processing proteinase.Biochem J2006
15381157Membrane type-1 matrix metalloproteinase (MT1-MMP) protects malignant cells from tumoricidal activity of re-engineered anthrax lethal toxin.Int J Biochem Cell Biol2005
16219679The transmembrane domain is essential for the microtubular trafficking of membrane type-1 matrix metalloproteinase (MT1-MMP).J Cell Sci2005
15944163Inhibition of membrane type-1 matrix metalloproteinase by cancer drugs interferes with the homing of diabetogenic T cells into the pancreas.J Biol Chem2005
15878869Membrane type-1 matrix metalloproteinase (MT1-MMP) exhibits an important intracellular cleavage function and causes chromosome instability.J Biol Chem2005
15983377Efficient synthetic inhibitors of anthrax lethal factor.Proc Natl Acad Sci U S A2005
14645246The low density lipoprotein receptor-related protein LRP is regulated by membrane type-1 matrix metalloproteinase (MT1-MMP) proteolysis in malignant cells.J Biol Chem2004
15574774Matrix metalloproteinase-26 is associated with estrogen-dependent malignancies and targets alpha1-antitrypsin serpin.Cancer Res2004
15260832Prointegrin maturation follows rapid trafficking and processing of MT1-MMP in Furin-Negative Colon Carcinoma LoVo Cells.Traffic2004
15375167Non-proteolytic, receptor/ligand interactions associate cellular membrane type-1 matrix metalloproteinase with the complement component C1q.J Biol Chem2004
15381670Cellular membrane type-1 matrix metalloproteinase (MT1-MMP) cleaves C3b, an essential component of the complement system.J Biol Chem2004
14729059Aberrant, persistent inclusion into lipid rafts limits the tumorigenic function of membrane type-1 matrix metalloproteinase in malignant cells.Exp Cell Res2004
12514192Membrane type-1 matrix metalloproteinase functions as a proprotein self-convertase. Expression of the latent zymogen in Pichia pastoris, autolytic activation, and the peptide sequence of the cleavage forms.J Biol Chem2003
11773076The hemopexin-like C-terminal domain of membrane type 1 matrix metalloproteinase regulates proteolysis of a multifunctional protein, gC1qR.J Biol Chem2002
12220632The cytoplasmic tail peptide sequence of membrane type-1 matrix metalloproteinase (MT1-MMP) directly binds to gC1qR, a compartment-specific chaperone-like regulatory protein.FEBS Lett2002
11724803Processing of integrin alpha(v) subunit by membrane type 1 matrix metalloproteinase stimulates migration of breast carcinoma cells on vitronectin and enhances tyrosine phosphorylation of focal adhesion kinase.J Biol Chem2002
11741954An alternative processing of integrin alpha(v) subunit in tumor cells by membrane type-1 matrix metalloproteinase.J Biol Chem2002
11389678Characterization of matrix metalloproteinase-26, a novel metalloproteinase widely expressed in cancer cells of epithelial origin.Biochem J2001
11335709Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.J Biol Chem2001
9829941RecA-independent pathways of lambdoid prophage induction in Escherichia coli.J Bacteriol1998
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Collaborators

Oregon Health & Science University Hospital.
Co-authored papers 4
Oregon Health & Science University
Co-authored papers 3
Cellstan-Immunoquant Inc.
Co-authored papers 3
University of California Riverside
Co-authored papers 3
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Oregon Health & Science University
Co-authored papers 2
Washington University School of Medicine
Co-authored papers 1
Oregon Health and Science University
Co-authored papers 1
Benaroya Research Institute at Virginia Mason
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Oregon Health and Science University
Co-authored papers 1
University of California
Co-authored papers 1
The Genome Institute, Washington University School of Medicine
Co-authored papers 1
IBM T.J. Watson Research Center
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Broad Institute of MIT and Harvard
Co-authored papers 1
Ontario Institute for Cancer Research
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Oregon Health and Science University
Co-authored papers 1
Gies College of Business, University of Illinois at Urbana-Champaign.
Co-authored papers 1
National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ)
Co-authored papers 1
Bill & Melinda Gates Foundation
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Biomolecular Engineering and UC Santa Cruz Genome Institute, University of California
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University of California at Santa Cruz
Co-authored papers 1
University of California los angeles
Co-authored papers 1
Washington University in St. Louis
Co-authored papers 1
Oregon Health and Science University
Co-authored papers 1
Biomolecular Engineering and UC Santa Cruz Genome Institute, University of California
Co-authored papers 1
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1