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Author Details

Rajesh Ambasudhan
The Scripps Research Institute
2003
32
26
PMIDPaper TitleJournal TitlePublished Year
32467645NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models.Mol Psychiatry2021
33833060Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.Proc Natl Acad Sci U S A2021
33226613Direct Reprogramming of Human Fibroblasts into Induced Neural Progenitor Cells Using Suicide Gene Embodied Episomal Vectors for Rapid Selection of Exogenous DNA-Free Cells.Methods Mol Biol2021
31782729Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls.Elife2019
29483518Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein.Nat Commun2018
30027906Parkinson's disease: what the model systems have taught us so far.J Genet2018
29523838Publisher Correction: Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer's disease.Nat Commun2018
29166608S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson's Disease Models.Cell Rep2017
29133852NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism.Nat Commun2017
29123083Identification of a peptide recognizing cerebrovascular changes in mouse models of Alzheimer's disease.Nat Commun2017
26877209Hydrogen Sulfide--Mechanisms of Toxicity and Development of an Antidote.Sci Rep2016
27821734Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons.Proc Natl Acad Sci U S A2016
26743041Elevated glucose and oligomeric β-amyloid disrupt synapses via a common pathway of aberrant protein S-nitrosylation.Nat Commun2016
25796565Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases.Neurobiol Dis2015
25692407Protection from cyanide-induced brain injury by the Nrf2 transcriptional activator carnosic acid.J Neurochem2015
24296783Small molecules enable OCT4-mediated direct reprogramming into expandable human neural stem cells.Cell Res2014
24756727Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell-derived neural progenitor cells.J Comp Neurol2014
23776240Aβ induces astrocytic glutamate release, extrasynaptic NMDA receptor activation, and synaptic loss.Proc Natl Acad Sci U S A2013
24290359Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription.Cell2013
22652035Direct lineage reprogramming to neural cells.Curr Opin Neurobiol2012
23136422High-frequency hippocampal oscillations activated by optogenetic stimulation of transplanted human ESC-derived neurons.J Neurosci2012
21525408Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors.Proc Natl Acad Sci U S A2011
21802386Direct reprogramming of adult human fibroblasts to functional neurons under defined conditions.Cell Stem Cell2011
21112560Reprogramming of human primary somatic cells by OCT4 and chemical compounds.Cell Stem Cell2010
19838168A chemical platform for improved induction of human iPSCs.Nat Methods2009
17884628An "orphan" finds a home in NSC regulation.Chem Biol2007
15671300Early-onset macular degeneration with drusen in a cynomolgus monkey (Macaca fascicularis) pedigree: exclusion of 13 candidate genes and loci.Invest Ophthalmol Vis Sci2005
15028284Atrophic macular degeneration mutations in ELOVL4 result in the intracellular misrouting of the protein.Genomics2004
15028285Characterization of mouse orthologue of ELOVL4: genomic organization and spatial and temporal expression.Genomics2004
12824221Evolutionarily conserved ELOVL4 gene expression in the vertebrate retina.Invest Ophthalmol Vis Sci2003
14517364Idiopathic cases of male infertility from a region in India show low incidence of Y-chromosome microdeletion.J Biosci2003
12882809Late-onset autosomal dominant macular dystrophy with choroidal neovascularization and nonexudative maculopathy associated with mutation in the RDS gene.Invest Ophthalmol Vis Sci2003
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Collaborators

Stuart A Lipton
The Scripps Research Institute, University of California
Co-authored papers 20
Nima Dolatabadi
The Scripps Research Institute
Co-authored papers 11
Maria Talantova
The Scripps Research Institute
Co-authored papers 8
Eliezer Masliah
National Institute On Aging
Co-authored papers 8
Tomohiro Nakamura
The Scripps Research Institute
Co-authored papers 7
Radha Ayyagari
Shiley Eye Institute, University of California San Diego
Co-authored papers 5
Abdullah Sultan
King Abdulaziz University
Co-authored papers 5
Dorit Trudler
Tel Aviv University
Co-authored papers 4
Swagata Ghatak
National Institute of Science Education and Research
Co-authored papers 3
John R Yates
TheScripps Research Institute
Co-authored papers 3
Amanda J Roberts
The Scripps Research Institute
Co-authored papers 2
Bing Shan
Co-authored papers 2
Kang Zhang
College of Animal Science and Technology, Guangxi University
Co-authored papers 2
Xuemei Han
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Richard Gao
University of Tubingen
Co-authored papers 1
Yin Wu
The Scripps Research Institute
Co-authored papers 1
Yaoyang Zhang
Co-authored papers 1
Nicholas J Schork
University of California San Diego
Co-authored papers 1
Yona Levites
Emory University School of Medicine
Co-authored papers 1
Daniel B McClatchy
Co-authored papers 1
Vivek Swarup
David Geffen School of Medicine, University of California los angeles
Co-authored papers 1
Todd E Golde
Emory Center for Neurodegenerative Disease
Co-authored papers 1
Matthew W Buczynski
Co-authored papers 1
Daniel H Geschwind
University of California los angeles
Co-authored papers 1
Xiaolei Wang
the First Affiliated Hospital of Anhui Medical University
Co-authored papers 1
Zhenyu Zhong
Co-authored papers 1
Bradley Voytek
Alfred P. Sloan Foundation, National Academy of Sciences, University of California Berkeley, University of California San Diego, University of California, San Diego
Co-authored papers 1
Alexander Y Andreyev
Co-authored papers 1
Rando Allikmets
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Release 1.2