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Author Details

Leen Slaets
50148Janssen Pharmaceutica NV
2014
25
15
PMIDPaper TitleJournal TitlePublished Year
36691849Population pharmacokinetic/pharmacodynamic models of JNJ-64794964, a toll-like receptor 7 agonist, in healthy adult participants.Antivir Ther2023
37199270A single, oral dose of the TLR7 agonist JNJ-64794964 induces transcriptomic and phenotypic changes in peripheral immune cells in healthy adults.Antivir Ther2023
35485332Safety, tolerability, pharmacokinetics, and pharmacodynamics of oral JNJ-64794964, a TLR-7 agonist, in healthy adults.Antivir Ther2021
30899086Molecular apocrine tumours in EORTC 10994/BIG 1-00 phase III study: pathological response after neoadjuvant chemotherapy and clinical outcomes.Br J Cancer2019
28929359Immunohistochemical versus molecular (BluePrint and MammaPrint) subtyping of breast carcinoma. Outcome results from the EORTC 10041/BIG 3-04 MINDACT trial.Breast Cancer Res Treat2018
28425345Surrogate marker analysis in cancer clinical trials through time-to-event mediation techniques.Stat Methods Med Res2018
29656866Corrigendum to "An association study of established breast cancer reproductive and lifestyle risk factors with tumour subtype defined by the prognostic 70-gene expression signature (MammaPrint<sup>®</sup>)" [Eur J Cancer 75 (April 2017) 5-13].Eur J Cancer2018
29092024Characterization of male breast cancer: results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program.Ann Oncol2018
28027521Correlation between severe infection and breast cancer metastases in the EORTC 10994/BIG 1-00 trial: Investigating innate immunity as a tumour suppressor in breast cancer.Eur J Cancer2017
28084333Male breast cancer precursor lesions: analysis of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program.Mod Pathol2017
28477490Characterisation of multifocal breast cancer using the 70-gene signature in clinical low-risk patients enrolled in the EORTC 10041/BIG 03-04 MINDACT trial.Eur J Cancer2017
28214658An association study of established breast cancer reproductive and lifestyle risk factors with tumour subtype defined by the prognostic 70-gene expression signature (MammaPrint<sup>®</sup>).Eur J Cancer2017
28292559Pathological characterisation of male breast cancer: Results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program.Eur J Cancer2017
28527420Factors predictive of locoregional recurrence following neoadjuvant chemotherapy in patients with large operable or locally advanced breast cancer: An analysis of the EORTC 10994/BIG 1-00 study.Eur J Cancer2017
26820652Discordant assessment of tumor biomarkers by histopathological and molecular assays in the EORTC randomized controlled 10041/BIG 03-04 MINDACT trial breast cancer : Intratumoral heterogeneity and DCIS or normal tissue components are unlikely to be the cause of discordance.Breast Cancer Res Treat2016
2755730070-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer.N Engl J Med2016
25578377Tumour size is the only predictive factor of distant recurrence after pathological complete response to neoadjuvant chemotherapy in patients with large operable or locally advanced breast cancers: a sub-study of EORTC 10994/BIG 1-00 phase III trial.Eur J Cancer2015
26488192[Axillary lymph node dissection versus axillary radiotherapy in patients with a positive sentinel node: the AMAROS trial].Ned Tijdschr Geneeskd2015
26025767Feasibility of a prospective, randomised, open-label, international multicentre, phase III, non-inferiority trial to assess the safety of active surveillance for low risk ductal carcinoma in situ - The LORD study.Eur J Cancer2015
25638681Radiotherapy or surgery for the axilla in node-positive breast cancer?--authors' reply.Lancet Oncol2015
25467016Neoadjuvant treatment with docetaxel plus lapatinib, trastuzumab, or both followed by an anthracycline-based chemotherapy in HER2-positive breast cancer: results of the randomised phase II EORTC 10054 study.Ann Oncol2015
24469641Mammographic screening detects low-risk tumor biology breast cancers.Breast Cancer Res Treat2014
24667714High concordance of protein (by IHC), gene (by FISH; HER2 only), and microarray readout (by TargetPrint) of ER, PgR, and HER2: results from the EORTC 10041/BIG 03-04 MINDACT trial.Ann Oncol2014
24529560Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis.Lancet2014
25439688Radiotherapy or surgery of the axilla after a positive sentinel node in breast cancer (EORTC 10981-22023 AMAROS): a randomised, multicentre, open-label, phase 3 non-inferiority trial.Lancet Oncol2014
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Collaborators

Champalimaud Clinical Center/Champalimaud Foundation
Co-authored papers 11
Merck & Co., Inc.
Co-authored papers 10
University of California San Francisco
Co-authored papers 8
Gloucestershire Hospitals NHS Foundation Trust
Co-authored papers 3
Erasmus MC Cancer Institute
Co-authored papers 3
Erasmus Medical Center (MC) Cancer Institute
Co-authored papers 3
Center for Statistics, Hasselt University
Co-authored papers 3
University of Edinburgh
Co-authored papers 3
Sahlgrenska University Hospital
Co-authored papers 3
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Leiden University Medical Center
Co-authored papers 3
Co-authored papers 2
Free University Hospital
Co-authored papers 2
University of Groningen, University Medical Center Groningen
Co-authored papers 2
Clinica Universidad de Navarra, Cancer Center Universidad de Navarra
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University Medical Center Utrecht
Co-authored papers 2
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
Leuven Cancer Institute and University Hospitals Leuven
Co-authored papers 1
Memorial Sloan Kettering Cancer Center, USA American Society of Clinical Oncology
Co-authored papers 1
Oncology Center of Excellence
Co-authored papers 1
Fred Hutchinson Cancer Research Center
Co-authored papers 1
Institut Jules Bordet
Co-authored papers 1
American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University
Co-authored papers 1
Beatson West of Scotland Cancer Centre
Co-authored papers 1
Lund University and Skane University Hospital
Co-authored papers 1
Ontario Institute for Cancer Research
Co-authored papers 1
Clinical Investigations Branch, National Cancer Institute
Co-authored papers 1