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Author Details

Joanna I Loizou
Center for Cancer Research, Comprehensive Cancer Centre, Medical University of Vienna
2002
43
22
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36929572Leveraging homologous recombination repair deficiency in sarcoma.EMBO Mol Med2023
37633982Mutational landscape of intestinal crypt cells after long-term in vivo exposure to high fat diet.Sci Rep2023
37259925A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability.Mol Syst Biol2023
34935929BioProfiling.jl: profiling biological perturbations with high-content imaging in single cells and heterogeneous populations.Bioinformatics2022
35708734Exploring the genetic space of the DNA damage response for cancer therapy through CRISPR-based screens.Mol Oncol2022
35719993Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy.Front Oncol2022
36400033POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells.Cell Rep2022
36400008POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps.Mol Cell2022
33109489Targeting the DNA Repair Enzyme Polymerase θ in Cancer Therapy.Trends Cancer2021
33513945Mutational Signatures Driven by Epigenetic Determinants Enable the Stratification of Patients with Gastric Cancer for Therapeutic Intervention.Cancers (Basel)2021
34672958Decomposing the mutational landscape of cancer genomes with RepairSig.Cell Syst2021
34539755Tissue Specific DNA Repair Outcomes Shape the Landscape of Genome Editing.Front Genet2021
34392967Tissue specificity of DNA repair: the CRISPR compass.Trends Genet2021
34333533High-throughput drug screening identifies the ATR-CHK1 pathway as a therapeutic vulnerability of CALR mutated hematopoietic cells.Blood Cancer J2021
34228493FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair.Mol Cell Biol2021
31123029High activation of STAT5A drives peripheral T-cell lymphoma and leukemia.Haematologica2020
32722390Interplay between Cellular Metabolism and the DNA Damage Response in Cancer.Cancers (Basel)2020
30808763<i>Klebsiella oxytoca</i> enterotoxins tilimycin and tilivalline have distinct host DNA-damaging and microtubule-stabilizing activities.Proc Natl Acad Sci U S A2019
31673055Genome-scale CRISPR screens are efficient in non-homologous end-joining deficient cells.Sci Rep2019
31387919Synthetic Lethal Interactions for Kinase Deficiencies to DNA Damage Chemotherapeutics.Cancer Res2019
31578334Publisher Correction: Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis.Nat Commun2019
31449058Polymerase δ deficiency causes syndromic immunodeficiency with replicative stress.J Clin Invest2019
31308374Human DEF6 deficiency underlies an immunodeficiency syndrome with systemic autoimmunity and aberrant CTLA-4 homeostasis.Nat Commun2019
29717121Validating the concept of mutational signatures with isogenic cell models.Nat Commun2018
29891926Map of synthetic rescue interactions for the Fanconi anemia DNA repair pathway identifies USP48.Nat Commun2018
29899063CDK6 Antagonizes p53-Induced Responses during Tumorigenesis.Cancer Discov2018
29089570Parallel genome-wide screens identify synthetic viable interactions between the BLM helicase complex and Fanconi anemia.Nat Commun2017
29149600Repair of UV-Induced DNA Damage Independent of Nucleotide Excision Repair Is Masked by MUTYH.Mol Cell2017
27149854A Comprehensive Analysis of the Dynamic Response to Aphidicolin-Mediated Replication Stress Uncovers Targets for ATM and ATMIN.Cell Rep2016
26455503Programmed DNA breaks in lymphoid cells: repair mechanisms and consequences in human disease.Immunology2016
27581360Perturbed hematopoiesis in mice lacking ATMIN.Blood2016
27922010MEK inhibitors block growth of lung tumours with mutations in ataxia-telangiectasia mutated.Nat Commun2016
26544571DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation.PLoS Genet2015
24695225Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy.Nature2014
25262557ATMIN is required for the ATM-mediated signaling and recruitment of 53BP1 to DNA damage sites upon replication stress.DNA Repair (Amst)2014
25281304DNA replication stress: causes, resolution and disease.Exp Cell Res2014
23219553Competition between NBS1 and ATMIN controls ATM signaling pathway choice.Cell Rep2012
21575860ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma.Cancer Cell2011
19880447Histone acetyltransferase cofactor Trrap is essential for maintaining the hematopoietic stem/progenitor cell pool.J Immunol2009
16341205Histone acetylation by Trrap-Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks.Nat Cell Biol2006
16582631Epigenetic information in chromatin: the code of entry for DNA repair.Cell Cycle2006
15066279The protein kinase CK2 facilitates repair of chromosomal DNA single-strand breaks.Cell2004
12198176Interference of papillomavirus E6 protein with single-strand break repair by interaction with XRCC1.EMBO J2002
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Collaborators

Marc Wiedner
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 9
Joana Ferreira da Silva
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 7
Michel Owusu
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 6
Abdelghani Mazouzi
Netherlands Cancer Institute
Co-authored papers 6
Georgia Velimezi
University of Patras
Co-authored papers 5
J??rg Menche
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 4
Christoph Bock
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 4
Robert Kralovics
Medical University of Vienna
Co-authored papers 4
Stefan Kubicek
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 4
Lydia Robinson-Garcia
CeMM Research Centre for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 3
Martin Moder
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 3
Zdenko Herceg
Co-authored papers 3
Michael Schuster
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 3
Stephen P Jackson
Mission Therapeutics Ltd. Glenn Berge Building
Co-authored papers 3
Serena Nik-Zainal
Early Cancer Institute, University of Cambridge
Co-authored papers 2
Kathleen M Fisch
Center for Computational Biology and Bioinformatics, University of California
Co-authored papers 1
Branka Radic-Sarikas
St. Anna Children's Cancer Research Institute (CCRI), Medical University of Vienna
Co-authored papers 1
Tianyi Zhang
National Institute on Aging, National Institutes of Health
Co-authored papers 1
Vivek Shukla
Chalmers University of Technology
Co-authored papers 1
Thomas Helleday
The University of Sheffield
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Haico van Attikum
Leiden University Medical Center
Co-authored papers 1
Matthias Farlik
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
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Jun Qin
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Sara Brin Rosenthal
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Release 1.2