Author details

Full Name

Paul Van Hummelen

Affiliation

ORCID

Career Start Year

1989

Papers

134

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36165930	Exploratory genomic analysis of high-grade neuroendocrine neoplasms across diverse primary sites.		2022
35771165	The Gastric Cancer Registry: A Genomic Translational Resource for Multidisciplinary Research in Gastric Cancer.	Cancer Epidemiol Biomarkers Prev	2022
35765145	Combining Donor-derived Cell-free DNA Fraction and Quantity to Detect Kidney Transplant Rejection Using Molecular Diagnoses and Histology as Confirmation.	Transplantation	2022
33370316	Meiotic susceptibility for induction of sperm with chromosomal aberrations in patients receiving combination chemotherapy for Hodgkin lymphoma.	PLoS ONE	2020
32193467	Whole genome analysis identifies the association of TP53 genomic deletions with lower survival in Stage III colorectal cancer.	Sci Rep	2020
32068070	ViroPanel: Hybrid Capture and Massively Parallel Sequencing for Simultaneous Detection and Profiling of Oncogenic Virus Infection and Tumor Genome.	Journal of Molecular Diagnostics	2020
29461635	Clinical and mutational spectrum of highly differentiated, paired box 3:forkhead box protein o1 fusion-negative rhabdomyosarcoma: A report from the Children's Oncology Group.	Cancer	2018
28786531	Feasibility of monitoring advanced melanoma patients using cell-free DNA from plasma.	Pigment Cell Melanoma Res	2018
29955181	Publisher Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29955182	Author Correction: Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
29713087	Molecular subtypes of diffuse large B cell lymphoma are associated with distinct pathogenic mechanisms and outcomes.	Nat Med	2018
28114446	Comparison of Prevalence and Types of Mutations in Lung Cancers Among Black and White Populations.	JAMA Oncol	2017
28713588	Genomic landscape of high-grade meningiomas.	NPJ Genom Med	2017
29263836	Erratum: Genomic landscape of high-grade meningiomas.	NPJ Genom Med	2017
29156680	Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAF[V600E].	Oncotarget	2017
28170043	Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas.	Neuro Oncol	2017
27882345	Institutional implementation of clinical tumor profiling on an unselected cancer population.	JCI Insight	2016
27016228	Tumor mutational analysis of GOG248, a phase II study of temsirolimus or temsirolimus and alternating megestrol acetate and tamoxifen for advanced endometrial cancer (EC): An NRG Oncology/Gynecologic Oncology Group study.	Gynecologic Oncology	2016
27329820	Integrated genetic and pharmacologic interrogation of rare cancers.	Nat Commun	2016
26829751	MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism.	Nat Genet	2016
26826201	Oncogenic PI3K mutations are as common as AKT1 and SMO mutations in meningioma.	Neuro Oncol	2016
27078850	Whole exome sequencing of urachal adenocarcinoma reveals recurrent NF1 mutations.	Oncotarget	2016
26773040	Diffuse large B-cell lymphoma patient-derived xenograft models capture the molecular and biological heterogeneity of the disease.	Blood	2016
27479034	The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.	Cancer Cell	2016
27070704	The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice.	Cancer Cell	2016
26487540	BRAF alteration status and the histone H3F3A gene K27M mutation segregate spinal cord astrocytoma histology.	Acta Neuropathol	2016
26702065	Targetable genetic features of primary testicular and primary central nervous system lymphomas.	Blood	2016
26410082	Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets.	Cancer Discov	2015
25626421	Genomic aberrations in cervical adenocarcinomas in Hong Kong Chinese women.	Int J Cancer	2015
25899310	MAP2K1 and MAP3K1 mutations in Langerhans cell histiocytosis.	Genes Chromosomes and Cancer	2015
25428359	BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers.	Nucleic Acids Res	2015
26636651	Metastasis-associated MCL1 and P16 copy number alterations dictate resistance to vemurafenib in a BRAFV600E patient-derived papillary thyroid carcinoma preclinical model.	Oncotarget	2015
26256760	Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective clinical trial and validation in a population-based registry.	Lancet Oncol	2015
26039708	Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have Prognostic Significance for Overall Survival in Platinum Treated Locally Advanced or Metastatic Urothelial Tumors.	PLoS One	2015
24652991	Somatic activating ARAF mutations in Langerhans cell histiocytosis.	Blood	2014
25589003	Sporadic hemangioblastomas are characterized by cryptic VHL inactivation.	Acta Neuropathol Commun	2014
25401468	Preexisting oncogenic events impact trastuzumab sensitivity in ERBB2-amplified gastroesophageal adenocarcinoma.	J Clin Invest	2014
25350844	Src mutation induces acquired lapatinib resistance in ERBB2-amplified human gastroesophageal adenocarcinoma models.	PLoS ONE	2014
25347344	Angiomatous meningiomas have a distinct genetic profile with multiple chromosomal polysomies including polysomy of chromosome 5.	Oncotarget	2014
24285721	Canonical nucleosome organization at promoters forms during genome activation.	Genome Research	2014
24413733	Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas.	Nat Genet	2014
25157968	Prospective enterprise-level molecular genotyping of a cohort of cancer patients.	J Mol Diagn	2014
24936796	Analysis and comparison of somatic mutations in paired primary and recurrent epithelial ovarian cancer samples.	PLoS One	2014
23334667	Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations.	Nat Genet	2013
24037752	Oncogenic mutations in cervical cancer: genomic differences between adenocarcinomas and squamous cell carcinomas of the cervix.	Cancer	2013
24066160	Colorectal cancers from distinct ancestral populations show variations in BRAF mutation frequency.	PLoS One	2013
23780909	Mutations in Hedgehog pathway genes in fetal rhabdomyomas.	J Pathol	2013
23052192	Hard-metal (WC-Co) particles trigger a signaling cascade involving p38 MAPK, HIF-1Î±, HMOX1, and p53 activation in human PBMC.	Archives of Toxicology	2013
23633565	Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.	Proc Natl Acad Sci U S A	2013
23417260	A universal fixation method based on quaternary ammonium salts (RNAlater) for omics-technologies: Saccharomyces cerevisiae as a case study.	Biotechnol Lett	2013