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Author Details

Robert V Farese
Harvard T.H. Chan School of Public Health
1962
461
113
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36096640Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum.Cold Spring Harb Perspect Biol2023
36096640Glycerolipid Synthesis and Lipid Droplet Formation in the Endoplasmic Reticulum.Cold Spring Harb Perspect Biol2023
37782317Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity.Elife2023
37150040Structure and function of lipid droplet assembly complexes.Curr Opin Struct Biol2023
37316513The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification.Nat Commun2023
36805337Fitm2 is required for ER homeostasis and normal function of murine liver.J Biol Chem2023
37248213Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.Nat Commun2023
37782317Mice lacking triglyceride synthesis enzymes in adipose tissue are resistant to diet-induced obesity.Elife2023
37316513The structure of phosphatidylinositol remodeling MBOAT7 reveals its catalytic mechanism and enables inhibitor identification.Nat Commun2023
37150040Structure and function of lipid droplet assembly complexes.Curr Opin Struct Biol2023
37248213Mechanism of action for small-molecule inhibitors of triacylglycerol synthesis.Nat Commun2023
36805337Fitm2 is required for ER homeostasis and normal function of murine liver.J Biol Chem2023
34583871The CYTOLD and ERTOLD pathways for lipid droplet-protein targeting.Trends Biochem Sci2022
35583926Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane.Elife2022
36207292Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.Nat Commun2022
34990551Key Factors Governing Initial Stages of Lipid Droplet Formation.J Phys Chem B2022
35210614Seipin forms a flexible cage at lipid droplet formation sites.Nat Struct Mol Biol2022
35134345The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.Dev Cell2022
34583871The CYTOLD and ERTOLD pathways for lipid droplet-protein targeting.Trends Biochem Sci2022
35583926Seipin transmembrane segments critically function in triglyceride nucleation and lipid droplet budding from the membrane.Elife2022
36207292Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.Nat Commun2022
35210614Seipin forms a flexible cage at lipid droplet formation sites.Nat Struct Mol Biol2022
34990551Key Factors Governing Initial Stages of Lipid Droplet Formation.J Phys Chem B2022
35134345The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology.Dev Cell2022
33463550The power of two: lessons from a scientific partnership.J Clin Invest2021
33593792Conditional targeting of phosphatidylserine decarboxylase to lipid droplets.Biol Open2021
33463550The power of two: lessons from a scientific partnership.J Clin Invest2021
34732896Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues.Nature2021
34616045An open-access volume electron microscopy atlas of whole cells and tissues.Nature2021
34951366Control of β-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-λ/ι and Nuclear Factor κ-B.Curr Alzheimer Res2021
34766133Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin-resistant forms of obesity and type 2 diabetes mellitus.MedComm (2020)2021
33593792Conditional targeting of phosphatidylserine decarboxylase to lipid droplets.Biol Open2021
34951366Control of β-Site Amyloid Precursor Protein-Cleaving Enzyme-1 Expression by Protein Kinase C-λ/ι and Nuclear Factor κ-B.Curr Alzheimer Res2021
34766133Roles of hepatic atypical protein kinase C hyperactivity and hyperinsulinemia in insulin-resistant forms of obesity and type 2 diabetes mellitus.MedComm (2020)2021
34616045An open-access volume electron microscopy atlas of whole cells and tissues.Nature2021
34732896Publisher Correction: An open-access volume electron microscopy atlas of whole cells and tissues.Nature2021
32345721Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant <i>wobbler</i> mice, a model of motor neuron degeneration.Proc Natl Acad Sci U S A2020
32433611Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.Nature2020
32023484Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.Mol Cell2020
32345721Inhibition of sphingolipid synthesis improves outcomes and survival in GARP mutant <i>wobbler</i> mice, a model of motor neuron degeneration.Proc Natl Acad Sci U S A2020
33147469Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.Cell Rep2020
32915949FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis.J Cell Biol2020
33176155A Systematic Protein Turnover Map for Decoding Protein Degradation.Cell Rep2020
32730754Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting.Dev Cell2020
32023484Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression.Mol Cell2020
33176155A Systematic Protein Turnover Map for Decoding Protein Degradation.Cell Rep2020
33147469Lipid Droplets in Brown Adipose Tissue Are Dispensable for Cold-Induced Thermogenesis.Cell Rep2020
32915949FIT2 is an acyl-coenzyme A diphosphatase crucial for endoplasmic reticulum homeostasis.J Cell Biol2020
32730754Determinants of Endoplasmic Reticulum-to-Lipid Droplet Protein Targeting.Dev Cell2020
32433611Structure and catalytic mechanism of a human triacylglycerol-synthesis enzyme.Nature2020
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Collaborators

Tobias C Walther
Harvard T. H. Chan School of Public Health
Co-authored papers 66
Gautam Bandyopadhyay
Co-authored papers 35
Chandramohan Chitraju
Co-authored papers 12
Bruce L Miller
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 10
Zon Weng Lai
Co-authored papers 10
Christopher B Newgard
Duke Molecular Physiology Institute
Co-authored papers 8
Niklas Mejhert
Karolinska Institutet
Co-authored papers 8
Natalie Krahmer
Co-authored papers 7
Fen-Biao Gao
Co-authored papers 7
Sebastian Boland
Co-authored papers 6
Florian Fr??hlich
Osnabruck University Department of Biology/Chemistry Bioanalytical Chemistry section
Co-authored papers 6
Matthew D Hirschey
Duke Molecular Physiology Institute, Duke University School of Medicine
Co-authored papers 6
Eric J Huang
University of California san francisco
Co-authored papers 6
Eric Verdin
Buck Institute for Research on Aging
Co-authored papers 5
Jorge Moscat
Co-authored papers 5
Robert D Stevens
Duke Molecular Physiology Institute
Co-authored papers 5
Maofu Liao
Harvard Medical School
Co-authored papers 5
Anna Karydas
Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 5
Gregory A Voth
Co-authored papers 5
Li Gan
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 5
Giovanni Coppola
David Geffen School of Medicine, University of California los angeles
Co-authored papers 4
Melanie Ott
Gladstone Institute of Virology
Co-authored papers 4
Aldons J Lusis
Co-authored papers 4
William W Seeley
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 4
Christer S Ejsing
VILLUM Center for Bioanalytical Sciences, University of Southern Denmark
Co-authored papers 4
J. Wade Harper
Harvard Medical School
Co-authored papers 3
Michael E Ward
National Institute of Neurological, National Institutes of Health (NIH)
Co-authored papers 3
Sakura Minami
Dokkyo Medical University
Co-authored papers 3
Daniel H Geschwind
University of California los angeles
Co-authored papers 3
Sandra Almeida
Co-authored papers 3
Release 1.2