Author details

Full Name

H R Kaback

Affiliation

University of California los angeles

ORCID

Career Start Year

1960

Papers

451

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37380079	InÂ vivo and inÂ vitro characterizations of melibiose permease (MelB) conformation-dependent nanobodies reveal sugar-binding mechanisms.	J Biol Chem	2023
37790566	Mobile barrier mechanisms for Na<sup>+</sup>-coupled symport in an MFS sugar transporter.	bioRxiv	2023
34929170	Investigation of sugar binding kinetics of the E.Â coli sugar/H<sup>+</sup> symporter XylE using solid-supported membrane-based electrophysiology.	J Biol Chem	2022
33472005	It's Better To Be Lucky Than Smart.	Annu Rev Biochem	2021
32380514	Diversity in kinetics correlated with structure in nano body-stabilized LacY.	PLoS One	2020
31889006	The proton electrochemical gradient induces a kinetic asymmetry in the symport cycle of LacY.	Proc Natl Acad Sci U S A	2020
32780424	Monoclonal antibody 4B1 influences the pK<sub>a</sub> of Glu325 in lactose permease (LacY) from EscherichiaÂ coli: evidence from SEIRAS.	FEBS Lett	2020
30792352	Arg302 governs the pK<sub>a</sub> of Glu325 in LacY.	Proc Natl Acad Sci U S A	2019
30801000	Insertion and folding pathways of single membrane proteins guided by translocases and insertases.	Sci Adv	2019
31147449	It takes two to tango: The dance of the permease.	J Gen Physiol	2019
29602806	Oversized galactosides as a probe for conformational dynamics in LacY.	Proc Natl Acad Sci U S A	2018
30108145	Crystal Structure of a ligand-bound LacY-Nanobody Complex.	Proc Natl Acad Sci U S A	2018
30478058	Engineered occluded apo-intermediate of LacY.	Proc Natl Acad Sci U S A	2018
28176812	Quantification of Detergents Complexed with Membrane Proteins.	Sci Rep	2017
28300394	An Asymmetric Conformational Change in LacY.	Biochemistry	2017
28154138	pK<sub>a</sub> of Glu325 in LacY.	Proc Natl Acad Sci U S A	2017
27438891	Role of Conserved Gly-Gly Pairs on the Periplasmic Side of LacY.	Biochemistry	2016
27791182	Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation.	Proc Natl Acad Sci U S A	2016
27686537	Thermodynamics of Nanobody Binding to Lactose Permease.	Biochemistry	2016
27595331	YidC assists the stepwise and stochastic folding of membrane proteins.	Nat Chem Biol	2016
27227677	pH Regulation of Electrogenic Sugar/H+ Symport in MFS Sugar Permeases.	PLoS One	2016
25568085	A chemiosmotic mechanism of symport.	Proc Natl Acad Sci U S A	2015
26512108	Transient conformers of LacY are trapped by nanobodies.	Proc Natl Acad Sci U S A	2015
26157133	Structure of LacY with an Î±-substituted galactoside: Connecting the binding site to the protonation site.	Proc Natl Acad Sci U S A	2015
25675534	Thermodynamic mechanism for inhibition of lactose permease by the phosphotransferase protein IIAGlc.	Proc Natl Acad Sci U S A	2015
25800555	Observing a lipid-dependent alteration in single lactose permeases.	Structure	2015
24389923	Structure-based mechanism for Na(+)/melibiose symport by MelB.	Nat Commun	2014
25512549	Outward-facing conformers of LacY stabilized by nanobodies.	Proc Natl Acad Sci U S A	2014
24872451	Real-time conformational changes in LacY.	Proc Natl Acad Sci U S A	2014
24520888	Galactoside-binding site in LacY.	Biochemistry	2014
24550316	Functional architecture of MFS D-glucose transporters.	Proc Natl Acad Sci U S A	2014
24711390	Substrate-induced changes in the structural properties of LacY.	Proc Natl Acad Sci U S A	2014
24453216	Structure of sugar-bound LacY.	Proc Natl Acad Sci U S A	2014
23530251	Evolutionary mix-and-match with MFS transporters.	Proc Natl Acad Sci U S A	2013
24152072	Electrophysiological characterization of uncoupled mutants of LacY.	Biochemistry	2013
24259711	Evolutionary mix-and-match with MFS transporters II.	Proc Natl Acad Sci U S A	2013
23962108	The periplasmic cavity of LacY mutant Cys154â¿¿Gly: how open is open?	Biochemistry	2013
23928306	YidC protein, a molecular chaperone for LacY protein folding via the SecYEG protein machinery.	J Biol Chem	2013
23671103	Trp replacements for tightly interacting Gly-Gly pairs in LacY stabilize an outward-facing conformation.	Proc Natl Acad Sci U S A	2013
22355148	Evidence for an intermediate conformational state of LacY.	Proc Natl Acad Sci U S A	2012
23033496	Role of protons in sugar binding to LacY.	Proc Natl Acad Sci U S A	2012
23000385	Proton-coupled dynamics in lactose permease.	Structure	2012
23012238	Apo-intermediate in the transport cycle of lactose permease (LacY).	Proc Natl Acad Sci U S A	2012
22930818	Dynamics of the L-fucose/H+ symporter revealed by fluorescence spectroscopy.	Proc Natl Acad Sci U S A	2012
22802658	Role of the irreplaceable residues in the LacY alternating access mechanism.	Proc Natl Acad Sci U S A	2012
21161516	The alternating access transport mechanism in LacY.	J Membr Biol	2011
21995338	Lactose permease and the alternating access mechanism.	Biochemistry	2011
22106930	Sugar recognition by CscB and LacY.	Biochemistry	2011
21896727	Opening the periplasmic cavity in lactose permease is the limiting step for sugar binding.	Proc Natl Acad Sci U S A	2011
21593407	Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition.	Proc Natl Acad Sci U S A	2011

1 - 50 of 451

Solmaz Sobhanifar

The University of British Columbia

Career Start Year 2005

Number of shared co-authors 1

Shalom D Goldberg

Janssen Pharmaceuticals

Career Start Year 2003

Number of shared co-authors 1

Joseph D O'Connell

Department of Pharmaceutical Chemistry, University of California-San Francisco

Career Start Year 2002

Number of shared co-authors 4

Anthony P Duff

Bragg Institute

Career Start Year 2000

Number of shared co-authors 1

Trevor F Moraes

University of Toronto, University Avenue

Career Start Year 2000

Number of shared co-authors 0

Alexei Savchenko

University of Toronto

Career Start Year 1997

Number of shared co-authors 1

Chad A Brautigam

UT Southwestern Medical Center

Career Start Year 1997

Number of shared co-authors 1

Geoffrey Chang

Skaggs School of Pharmacy and Pharmaceutical Sciences.

Career Start Year 1994

Number of shared co-authors 2

Mark Goulian

University of Pennsylvania

Career Start Year 1991

Number of shared co-authors 1

Marc-Andr?? Elsliger

Joint Center for Structural Genomics

Career Start Year 1989

Number of shared co-authors 0

Karen N Allen

Boston University

Career Start Year 1989

Number of shared co-authors 2

Hiroyuki Mori

Institute for Life and Medical Sciences, Kyoto University

Career Start Year 1989

Number of shared co-authors 0

Natalie C J Strynadka

The University of British Columbia

Career Start Year 1988

Number of shared co-authors 1

Scott A Lesley

Merck & Co., Inc.

Career Start Year 1987

Number of shared co-authors 1

John F Hunt

Columbia University

Career Start Year 1986

Number of shared co-authors 1

Michael C Wiener

University of Virginia

Career Start Year 1986

Number of shared co-authors 2

Tanneke den Blaauwen

Swammerdam Institute for Life Sciences, University of Amsterdam

Career Start Year 1985

Number of shared co-authors 0

Christian Cambillau

Aix Marseille University and CNRS

Career Start Year 1984

Number of shared co-authors 1

Andrzej Joachimiak

Center for Structural Biology of Infectious Diseases, University of Chicago

Career Start Year 1979

Number of shared co-authors 4

Gordon S Rule

Carnegie Mellon University

Career Start Year 1978

Number of shared co-authors 3

Ivan Rayment

College of Agricultural and Life Sciences, University of Wisconsin-Madison

Career Start Year 1976

Number of shared co-authors 2

Anthony M George

University of Technology

Career Start Year 1976

Number of shared co-authors 0

Douglas C Rees

Howard Hughes Medical Institute, California Institute of Technology

Career Start Year 1974

Number of shared co-authors 4

John A Gerlt

University of Illinois at Urbana-Champaign

Career Start Year 1973

Number of shared co-authors 2

Frank M Raushel

Texas A&M University, College Station

Career Start Year 1973

Number of shared co-authors 1

Antoine Danchin

University of Hong Kong

Career Start Year 1969

Number of shared co-authors 2

John E Cronan

University of Illinois

Career Start Year 1967

Number of shared co-authors 1

Jeffrey Tze-Fei Wong

The Hong Kong University of Science and Technology

Career Start Year 1961

Number of shared co-authors 0

Masayori Inouye

Robert Wood Johnson Medical School, Rutgers University

Career Start Year 1961

Number of shared co-authors 1

Milton H Saier

University of California at San Diego

Career Start Year 1951

Number of shared co-authors 0

row(s) 1 - 30 of 30

Yonggang Zhou

David Geffen School of Medicine, University of California at Los Angeles

Co-authored papers 7

Julian P Whitelegge

Co-authored papers 6

Bengt Persson

Karolinska Institutet

Co-authored papers 6

Kym F Faull

Co-authored papers 5

Jeff Abramson

Co-authored papers 5

Robert M Stroud

University of California San Francisco

Co-authored papers 5

Arun H S Kumar

Sher-i-Kashmir Institute of Medical Sciences

Co-authored papers 4

Janet Finer-Moore

University of California San Francisco

Co-authored papers 4

Stephen H White

Co-authored papers 2

Vincent Chaptal

Co-authored papers 2

Simon A Levin

Co-authored papers 1

Daniel L Minor

Cardiovascular Research Institute, University of California san francisco

Co-authored papers 1

Henning Stahlberg

Ecole Polytechnique Federale de Lausanne (EPFL), University of Lausanne

Co-authored papers 1

J. B Heymann

Frederick National Laboratory for Cancer Research, Inc.

Co-authored papers 1

Lukasz Salwinski

university of california los angeles

Co-authored papers 1

Ad Bax

National Institutes of Health

Co-authored papers 1

Richard L Sidman

Harvard Medical School

Co-authored papers 1

Edward F DeLong

University of Hawai'i at Manoa

Co-authored papers 1

Pamela J Bjorkman

Co-authored papers 1

James M Holton

Lawrence Berkeley National Laboratory

Co-authored papers 1

Robert M Friedman

J. Craig Venter Institute

Co-authored papers 1

Terry A Krulwich

Co-authored papers 1

Robert Haselkorn

University of Chicago

Co-authored papers 1

Michael R Botchan

University of California berkeley

Co-authored papers 1

Michael G Rossmann

Purdue University

Co-authored papers 1

Seth A Darst

The Rockefeller University

Co-authored papers 1

Solomon H Snyder

Co-authored papers 1

Steve A Kay

Keck School of Medicine, University of Southern California

Co-authored papers 1

Elizabeth H Blackburn

University of California san francisco

Co-authored papers 1

Witek Kwiatkowski

Swiss Federal Institute of Technology

Co-authored papers 1

1 - 30

Author Details

Column Actions

Recommended Authors

Collaborators