Author details

Full Name

Robert M Plenge

Affiliation

ORCID

Career Start Year

1996

Papers

140

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36829046	Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population.	Nature	2023
36653562	FinnGen provides genetic insights from a well-phenotyped isolated population.	Nature	2023
32706364	Molecular Underpinnings of Severe Coronavirus Disease 2019.	JAMA - Journal of the American Medical Association	2020
30883600	Correction: Epidemiology and treatment patterns of rheumatoid arthritis in a large cohort of Arab patients.	PLoS One	2019
31748751	High-throughput phenotyping with electronic medical record data using a common semi-supervised approach (PheCAP).	Nat Protoc	2019
31253975	Priority index for human genetics and drug discovery.	Nature Genetics	2019
30566451	Epidemiology and treatment patterns of rheumatoid arthritis in a large cohort of Arab patients.	PLoS One	2018
29875488	Genomic atlas of the human plasma proteome.	Nature	2018
30327483	Phenome-wide association studies across large population cohorts support drug target validation.	Nat Commun	2018
28118524	A Multinational Arab Genome-Wide Association Study Identifies New Genetic Associations for Rheumatoid Arthritis.	Arthritis Rheumatol	2017
28406199	Biomedicine: Human genes lost and their functions found.	Nature	2017
28831053	Large Scale Metabolic Profiling identifies Novel Steroids linked to Rheumatoid Arthritis.	Sci Rep	2017
27788309	Brief Report: The Role of Rare Protein-Coding Variants in Anti-Tumor Necrosis Factor Treatment Response in Rheumatoid Arthritis.	Arthritis Rheumatol	2017
27721464	Erratum: Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis.	Nat Commun	2016
25966632	Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes.	Eur J Hum Genet	2016
27464747	Disciplined approach to drug discovery and early development.	Science Translational Medicine	2016
26386125	Loci associated with N-glycosylation of human IgG are not associated with rheumatoid arthritis: a Mendelian randomisation study.	Ann Rheum Dis	2016
27626929	The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1.	PLoS Genet	2016
24532676	High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci.	Ann Rheum Dis	2015
25834819	TRAF1/C5 but not PTPRC variants are potential predictors of rheumatoid arthritis response to anti-tumor necrosis factor therapy.	Biomed Res Int	2015
25667207	Lack of gene-diuretic interactions on the risk of incident gout: the Nurses' Health Study and Health Professionals Follow-up Study.	Ann Rheum Dis	2015
25777314	Accuracy of the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) as a research tool for identification of patients with uveitis and scleritis.	Ophthalmic Epidemiol	2015
25849893	TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.	PLoS One	2015
26517366	Somatic Variation of T-Cell Receptor Genes Strongly Associate with HLA Class Restriction.	PLoS One	2015
26301417	Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts.	PLoS One	2015
26286434	New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis.	Int J Epidemiol	2015
24448344	Identification of secreted phosphoprotein 1 gene as a new rheumatoid arthritis susceptibility gene.	Ann Rheum Dis	2015
24092415	A weighted genetic risk score using all known susceptibility variants to estimate rheumatoid arthritis risk.	Ann Rheum Dis	2015
25062868	Improving the power of genetic association tests with imperfect phenotype derived from electronic medical records.	Hum Genet	2014
25453756	A role for noncoding variation in schizophrenia.	Cell Rep	2014
25524867	HLA-DRB1-associated rheumatoid arthritis risk at multiple levels in African Americans: hierarchical classification systems, amino acid positions, and residues.	Arthritis Rheumatol	2014
25521360	Genomic architecture of pharmacological efficacy and adverse events.	Pharmacogenomics	2014
24390342	Genetics of rheumatoid arthritis contributes to biology and drug discovery.	Nature	2014
24385024	The influence of polygenic risk scores on heritability of anti-CCP level in RA.	Genes Immun	2014
24276088	Genome-wide association studies to advance our understanding of critical cell types and pathways in rheumatoid arthritis: recent findings and challenges.	Curr Opin Rheumatol	2014
23716066	Association between low density lipoprotein and rheumatoid arthritis genetic factors with low density lipoprotein levels in rheumatoid arthritis and non-rheumatoid arthritis controls.	Ann Rheum Dis	2014
24911414	Allele-specific methylation occurs at genetic variants associated with complex disease.	PLoS One	2014
25033836	(Epi)Genetic analyses of age-related macular degeneration: case-control and discordant twin studies.	Hum Hered	2014
24520335	Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene.	PLoS One	2014
24656864	Fine mapping seronegative and seropositive rheumatoid arthritis to shared and distinct HLA alleles by adjusting for the effects of heterogeneity.	Am J Hum Genet	2014
24513692	Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance).	Pharmacogenomics J	2014
23696745	Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway.	PLoS Genet	2013
23007924	Association of rheumatoid arthritis risk alleles with response to anti-TNF biologics: results from the CORRONA registry and meta-analysis.	Inflammation	2013
23868113	Validating therapeutic targets through human genetics.	Nat Rev Drug Discov	2013
24385918	Quantifying missing heritability at known GWAS loci.	PLoS Genet	2013
24022229	Identification of BACH2 and RAD51B as rheumatoid arthritis susceptibility loci in a meta-analysis of genome-wide data.		2013
23976944	Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records.	PLoS One	2013
24244385	Modeling disease severity in multiple sclerosis using electronic health records.	PLoS One	2013
23751398	Normalization of plasma 25-hydroxy vitamin D is associated with reduced risk of surgery in Crohn's disease.	Inflamm Bowel Dis	2013
23925980	Lipid and lipoprotein levels and trend in rheumatoid arthritis compared to the general population.	Arthritis Care Res (Hoboken)	2013