Skip to Main Content

Author Details

Nir London
The Weizmann Institute of Science
2007
66
31
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36738297Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry.J Am Chem Soc2023
38040731A simple method for developing lysine targeted covalent protein reagents.Nat Commun2023
36819852Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells.Chem Sci2023
36738297Sulfamate Acetamides as Self-Immolative Electrophiles for Covalent Ligand-Directed Release Chemistry.J Am Chem Soc2023
38040731A simple method for developing lysine targeted covalent protein reagents.Nat Commun2023
36819852Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells.Chem Sci2023
35191598Expanding the Repertoire of Low-Molecular-Weight Pentafluorosulfanyl-Substituted Scaffolds.ChemMedChem2022
35912476Optimization of Covalent MKK7 Inhibitors <i>via</i> Crude Nanomole-Scale Libraries.J Med Chem2022
35961788Kidney Failure Alters Parathyroid Pin1 Phosphorylation and Parathyroid Hormone mRNA-Binding Proteins, Leading to Secondary Hyperparathyroidism.J Am Soc Nephrol2022
36544740Structure-guided design and characterization of a clickable, covalent PARP16 inhibitor.Chem Sci2022
35191598Expanding the Repertoire of Low-Molecular-Weight Pentafluorosulfanyl-Substituted Scaffolds.ChemMedChem2022
36544740Structure-guided design and characterization of a clickable, covalent PARP16 inhibitor.Chem Sci2022
35912476Optimization of Covalent MKK7 Inhibitors <i>via</i> Crude Nanomole-Scale Libraries.J Med Chem2022
35961788Kidney Failure Alters Parathyroid Pin1 Phosphorylation and Parathyroid Hormone mRNA-Binding Proteins, Leading to Secondary Hyperparathyroidism.J Am Soc Nephrol2022
33972797Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.Nat Chem Biol2021
34127864A white-knuckle ride of open COVID drug discovery.Nature2021
33972797Sulfopin is a covalent inhibitor of Pin1 that blocks Myc-driven tumors in vivo.Nat Chem Biol2021
34174194An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 M<sup>pro</sup> inhibitor.Cell Chem Biol2021
33902949Electrophilic Natural Products as Drug Discovery Tools.Trends Pharmacol Sci2021
34008627Discovery of SARS-CoV-2 main protease inhibitors using a synthesis-directed <i>de novo</i> design model.Chem Commun (Camb)2021
34055615Proteolysis Targeting Chimeras for BTK Efficiently Inhibit B-Cell Receptor Signaling and Can Overcome Ibrutinib Resistance in CLL Cells.Front Oncol2021
34101963Intracellular Protein-Drug Interactions Probed by Direct Mass Spectrometry of Cell Lysates.Angew Chem Int Ed Engl2021
33761747Tunable Methacrylamides for Covalent Ligand Directed Release Chemistry.J Am Chem Soc2021
33549806The rise of covalent proteolysis targeting chimeras.Curr Opin Chem Biol2021
34326184Cross-reactive antibodies against human coronaviruses and the animal coronavirome suggest diagnostics for future zoonotic spillovers.Sci Immunol2021
34388391Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.Cell2021
34817989Site-Specific Labeling of Endogenous Proteins Using CoLDR Chemistry.J Am Chem Soc2021
34476063Covalent flexible peptide docking in Rosetta.Chem Sci2021
33902949Electrophilic Natural Products as Drug Discovery Tools.Trends Pharmacol Sci2021
33761747Tunable Methacrylamides for Covalent Ligand Directed Release Chemistry.J Am Chem Soc2021
33549806The rise of covalent proteolysis targeting chimeras.Curr Opin Chem Biol2021
34817989Site-Specific Labeling of Endogenous Proteins Using CoLDR Chemistry.J Am Chem Soc2021
34388391Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy.Cell2021
34476063Covalent flexible peptide docking in Rosetta.Chem Sci2021
34101963Intracellular Protein-Drug Interactions Probed by Direct Mass Spectrometry of Cell Lysates.Angew Chem Int Ed Engl2021
34326184Cross-reactive antibodies against human coronaviruses and the animal coronavirome suggest diagnostics for future zoonotic spillovers.Sci Immunol2021
34127864A white-knuckle ride of open COVID drug discovery.Nature2021
34174194An automatic pipeline for the design of irreversible derivatives identifies a potent SARS-CoV-2 M<sup>pro</sup> inhibitor.Cell Chem Biol2021
34008627Discovery of SARS-CoV-2 main protease inhibitors using a synthesis-directed <i>de novo</i> design model.Chem Commun (Camb)2021
34055615Proteolysis Targeting Chimeras for BTK Efficiently Inhibit B-Cell Receptor Signaling and Can Overcome Ibrutinib Resistance in CLL Cells.Front Oncol2021
32369353Efficient Targeted Degradation via Reversible and Irreversible Covalent PROTACs.J Am Chem Soc2020
32369353Efficient Targeted Degradation via Reversible and Irreversible Covalent PROTACs.J Am Chem Soc2020
32401033A Fast and Clean BTK Inhibitor.J Med Chem2020
32483379Identification of a potent and selective covalent Pin1 inhibitor.Nat Chem Biol2020
32483333Macromolecular modeling and design in Rosetta: recent methods and frameworks.Nat Methods2020
32931911Structural basis for producing selective MAP2K7 inhibitors.Bioorg Med Chem Lett2020
33028810Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease.Nat Commun2020
32520539Correction to Efficient Targeted Degradation via Reversible and Irreversible Covalent PROTACs.J Am Chem Soc2020
33177718HSP40 proteins use class-specific regulation to drive HSP70 functional diversity.Nature2020
32568546Hitting KRAS When It's Down.J Med Chem2020
  • 1 - 50 of 132

Recommended Authors

Matthew J O'Meara
University of Michigan ann arbor
Career Start Year 2013
Number of shared co-authors 20
Daniel Carbajo
Institut de Quimica Avancada de Catalunya (IQAC-CSIC)
Career Start Year 2011
Number of shared co-authors 0
Sarah Barelier
CNRS, Aix-Marseille University
Career Start Year 2009
Number of shared co-authors 4
Guillaume Poncet-Montange
Center for the Development of Therapeutics, Broad Institute of MIT & Harvard
Career Start Year 2007
Number of shared co-authors 2
Jacob D Durrant
University of Pittsburgh
Career Start Year 2006
Number of shared co-authors 0
Dima Kozakov
Stony Brook University
Career Start Year 2005
Number of shared co-authors 31
Jianwei Che
Dana-Farber Cancer Institute
Career Start Year 2005
Number of shared co-authors 2
Priyadarshini Jaishankar
Department of Pharmaceutical Chemistry, University of California san francisco
Career Start Year 2005
Number of shared co-authors 0
Gerald H Lushington
Inc. 16 Dekalb Pike
Career Start Year 2002
Number of shared co-authors 0
Noel Southall
National Center for Advancing Translational Sciences, National Institutes of Health
Career Start Year 2002
Number of shared co-authors 0
Alan M Sandercock
MedImmune Ltd.
Career Start Year 2001
Number of shared co-authors 1
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Career Start Year 2000
Number of shared co-authors 12
Efrat Ben-Zeev
Grand Israel National Center for Personalized Medicine, Weizmann Institute of Science
Career Start Year 1999
Number of shared co-authors 22
Heather A Carlson
University of Michigan ann arbor
Career Start Year 1999
Number of shared co-authors 2
David R Hall
Diamond Light Source Ltd, Harwell Science & Innovation Campus
Career Start Year 1998
Number of shared co-authors 27
Erik Verschueren
University of California San Francisco
Career Start Year 1997
Number of shared co-authors 3
Dmitri Beglov
Boston University
Career Start Year 1997
Number of shared co-authors 27
Rodrigo J Carbajo
Oncology R&D
Career Start Year 1997
Number of shared co-authors 1
Eric Feyfant
Schrodinger Inc.
Career Start Year 1997
Number of shared co-authors 1
Pavel Strop
Pfizer Inc.
Career Start Year 1997
Number of shared co-authors 1
Shane Atwell
Lilly Research Laboratories
Career Start Year 1994
Number of shared co-authors 7
Aw Edith Chan
The Walter and Eliza Hall Institute of Medical Research
Career Start Year 1993
Number of shared co-authors 1
Herman W T van Vlijmen
Leiden Academic Centre for Drug Research (LACDR), Leiden University
Career Start Year 1988
Number of shared co-authors 2
Gerhard Klebe
Institut fur Pharmazeutische Chemie, Philipps-Universitat Marburg
Career Start Year 1988
Number of shared co-authors 6
Diane Joseph-McCarthy
Boston University
Career Start Year 1987
Number of shared co-authors 3
Stuart L Schreiber
Broad Institute
Career Start Year 1985
Number of shared co-authors 7
Stefan Knapp
Institute of Pharmaceutical Chemistry, Goethe University
Career Start Year 1983
Number of shared co-authors 11
Sandor Vajda
Boston University
Career Start Year 1982
Number of shared co-authors 32
Ruben Abagyan
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California
Career Start Year 1981
Number of shared co-authors 2
James A Wells
Department of Pharmaceutical Chemistry, University of California San Francisco
Career Start Year 1974
Number of shared co-authors 9

Collaborators

Ora Schueler-Furman
Co-authored papers 24
Barak Raveh
The Hebrew University of Jerusalem
Co-authored papers 11
Brian K Shoichet
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
David Baker
University of Washington
Co-authored papers 3
Nathanael S Gray
Harvard Medical School
Co-authored papers 3
Shira Albeck
Weizmann Institute of Science
Co-authored papers 3
Tamar Unger
Weizmann Institute of Science
Co-authored papers 3
Brian Kuhlman
Co-authored papers 2
Peter Cimermancic
Verily Life Sciences LLC
Co-authored papers 2
Sarel J Fleishman
Co-authored papers 2
Jeffrey J Gray
Johns Hopkins University
Co-authored papers 2
John J Irwin
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Hahnbeom Park
Co-authored papers 2
Brian G Pierce
University of Maryland Institute for Bioscience and Biotechnology Research
Co-authored papers 2
Jack Taunton
University of California san francisco
Co-authored papers 2
Patricia C Babbitt
University of California san francisco
Co-authored papers 2
Sirano Dhe-Paganon
Dana-Farber Cancer Institute
Co-authored papers 2
Haim J Wolfson
Tel Aviv University
Co-authored papers 1
Gerburg M Wulf
Co-authored papers 1
Eran Segal
Weizmann Institute of Science
Co-authored papers 1
Omar Demerdash
Co-authored papers 1
Jérôme Azé
Co-authored papers 1
Zhiping Weng
University of Massachusetts Medical School
Co-authored papers 1
Galen J Correy
University of California san francisco
Co-authored papers 1
Seren Soner
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Kala Bharath Pilla
Quantitative Biology Institute, University of California san francisco
Co-authored papers 1
Charles H Robert
Co-authored papers 1
Shiyong Liu
Co-authored papers 1
Aroop Sircar
Co-authored papers 1
Release 1.2