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Author Details

John M Streicher
2002
73
24
PMIDPaper TitleJournal TitlePublished Year
34826881Strategies towards safer opioid analgesics-A review of old and upcoming targets.British Journal of Pharmacology2023
36245395The natural product argentatin C attenuates postoperative pain via inhibition of voltage-gated sodium and T-type voltage-gated calcium channels.British Journal of Pharmacology2023
37873212The Role of Ryanodine Receptor 2 in Drug-Associated Learning.2023
37034662Terpenes from <i>Cannabis sativa</i> Induce Antinociception in Mouse Chronic Neuropathic Pain via Activation of Spinal Cord Adenosine A<sub>2A</sub> Receptors.bioRxiv2023
36651179Design of Analgesic Trivalent Peptides with Low Withdrawal Symptoms: Probing the Antinociceptive Profile of Novel Linear and Cyclic Peptides as Opioid Pan Ligands.2023
37059218The D3 receptor antagonist SR 21502 reduces cue-induced reinstatement of methamphetamine-seeking in rats.2023
36937877The role of opioid receptors in modulating Alzheimer's Disease.2023
36793431Structure-Based Design of Glycosylated Oxytocin Analogues with Improved Selectivity and Antinociceptive Activity.2023
37040443HSP90 inhibition in the mouse spinal cord enhances opioid signaling by suppressing an AMPK-mediated negative feedback loop.2023
35237767Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism.2022
36015292Inhibition of HSP90 Preserves Blood-Brain Barrier Integrity after Cortical Spreading Depression.Pharmaceutics2022
35890365Extracellular Alterations in pH and K+ Modify the Murine Brain Endothelial Cell Total and Phospho-Proteome.Pharmaceutics2022
35790399Age-Induced Changes in μ-Opioid Receptor Signaling in the Midbrain Periaqueductal Gray of Male and Female Rats.Journal of Neuroscience2022
36385929Discovery of κ Opioid Receptor (KOR)-Selective d-Tetrapeptides with Improved Antinociceptive Effect after Peripheral Administration.ACS Medicinal Chemistry Letters2022
34252907Antagonism of the mu-delta opioid receptor heterodimer enhances opioid antinociception by activating Src and calcium/calmodulin-dependent protein kinase II signaling.Pain2022
35335399Correction: Tanguturi et al. Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists. 2021, , 6693.Molecules2022
34771099Discovery of Novel Delta Opioid Receptor (DOR) Inverse Agonist and Irreversible (Non-Competitive) Antagonists.Molecules2021
33859287Cannabis sativa terpenes are cannabimimetic and selectively enhance cannabinoid activity.Scientific Reports2021
34072734Multifunctional Enkephalin Analogs with a New Biological Profile: MOR/DOR Agonism and KOR Antagonism.Biomedicines2021
33031872Use of home cage wheel running to assess the behavioural effects of administering a mu/delta opioid receptor heterodimer antagonist for spontaneous morphine withdrawal in the rat.Behavioural Brain Research2021
34443519Synthesis and In Vitro Characterization of Glycopeptide Drug Candidates Related to PACAP.Molecules2021
34663685Analgesic Potential of Terpenes Derived from .Pharmacological Reviews2021
31201990A Novel Mu-Delta Opioid Agonist Demonstrates Enhanced Efficacy With Reduced Tolerance and Dependence in Mouse Neuropathic Pain Models.Journal of Pain2020
32427747Daily intermittent fasting in mice enhances morphine-induced antinociception while mitigating reward, tolerance, and constipation.Pain2020
32371496Inhibition of Hsp90 in the spinal cord enhances the antinociceptive effects of morphine by activating an ERK-RSK pathway.Science Signaling2020
31834798Potent, Efficacious, and Stable Cyclic Opioid Peptides with Long Lasting Antinociceptive Effect after Peripheral Administration.Journal of Medicinal Chemistry2020
32112361The endomorphin-1/2 and dynorphin-B peptides display biased agonism at the mu opioid receptor.2020
32435376Developing Cyclic Opioid Analogues: Fluorescently Labeled Bioconjugates of Biphalin.ACS Medicinal Chemistry Letters2020
32541387A modulator of the low-voltage-activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies.Pain2020
32701840Heat shock protein 90 inhibitors block the antinociceptive effects of opioids in mouse chemotherapy-induced neuropathy and cancer bone pain models.Pain2020
32530286Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects.Journal of Medicinal Chemistry2020
33170687Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template.Journal of Medicinal Chemistry2020
33424551Editorial: Novel Molecular Targets for the Treatment of Pain.Frontiers in Molecular Neuroscience2020
30933958Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy.Pain2019
31849607The Alpha Isoform of Heat Shock Protein 90 and the Co-chaperones p23 and Cdc37 Promote Opioid Anti-nociception in the Brain.Frontiers in Molecular Neuroscience2019
30169422Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury-associated peripheral sensory neuropathy via block of N- and T-type calcium channels.Pain2019
30525440(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels.ACS Chem Neurosci2019
31170174Comprehensive molecular pharmacology screening reveals potential new receptor interactions for clinically relevant opioids.PLoS ONE2019
31421708The role of heat shock protein 90 in regulating pain, opioid signaling, and opioid antinociception.Vitamins and Hormones2019
30962495On resin click-chemistry-mediated synthesis of novel enkephalin analogues with potent anti-nociceptive activity.Scientific Reports2019
30670482The Role of Heat Shock Proteins in Regulating Receptor Signal Transduction.Molecular Pharmacology2019
30996778Novel Cyclic Biphalin Analogues by Ruthenium-Catalyzed Ring Closing Metathesis: and Biological Profile.ACS Medicinal Chemistry Letters2019
29371114A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain.Journal of Pain2018
28946783Peripherally Acting μ-Opioid Receptor Antagonists for the Treatment of Opioid-Related Side Effects: Mechanism of Action and Clinical Implications.Journal of Pharmacy Practice2018
29939746Synthesis and Evaluation of a Novel Bivalent Selective Antagonist for the Mu-Delta Opioid Receptor Heterodimer that Reduces Morphine Withdrawal in Mice.Journal of Medicinal Chemistry2018
29703898TAK1 activation of alpha-TAT1 and microtubule hyperacetylation control AKT signaling and cell growth.Nature Communications2018
28699350Analgesic Properties of Opioid/NK1 Multitarget Ligands with Distinct in Vitro Profiles in Naive and Chronic Constriction Injury Mice.ACS Chemical Neuroscience2017
28948607Synergistic interaction of the cannabinoid and death receptor systems - a potential target for future cancer therapies?FEBS Letters2017
28635314Fluorescent-labeled bioconjugates of the opioid peptides biphalin and DPDPE incorporating fluorescein-maleimide linkers.Future Medicinal Chemistry2017
28450396Heat-shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK mitogen-activated protein kinase (MAPK) mechanism in mouse brain.Journal of Biological Chemistry2017
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