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Author Details

Frank R Sharp
University of California at Davis Medical Center
1969
391
90
PMIDPaper TitleJournal TitlePublished Year
36803375Monocyte, neutrophil, and whole blood transcriptome dynamics following ischemic stroke.BMC Med2023
35821378Sustained ICP Elevation Is a Driver of Spatial Memory Deficits After Intraventricular Hemorrhage and Leads to Activation of Distinct Microglial Signaling Pathways.Transl Stroke Res2023
36691064Early peripheral blood gene expression associated with good and poor 90-day ischemic stroke outcomes.J Neuroinflammation2023
36845656White matter injury, cholesterol dysmetabolism, and APP/Abeta dysmetabolism interact to produce Alzheimer's disease (AD) neuropathology: A hypothesis and review.Front Aging Neurosci2023
35109711Combined Inhibition of Fyn and c-Src Protects Hippocampal Neurons and Improves Spatial Memory via ROCK after Traumatic Brain Injury.J Neurotrauma2022
36936603Gene expression changes implicate specific peripheral immune responses to Deep and Lobar Intracerebral Hemorrhages in humans.Brain Hemorrhages2022
35213696Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke.Brain2022
35325079Progression of cerebral white matter hyperintensities is related to leucocyte gene expression.Brain2022
32960689Distinct peripheral blood monocyte and neutrophil transcriptional programs following intracerebral hemorrhage and different etiologies of ischemic stroke.J Cereb Blood Flow Metab2021
33641386Aging Immune System in Acute Ischemic Stroke: A Transcriptomic Analysis.Stroke2021
33753837Bacterial lipopolysaccharide is associated with stroke.Sci Rep2021
34899263Lipopolysaccharide, Identified Using an Antibody and by PAS Staining, Is Associated With <i>Corpora amylacea</i> and White Matter Injury in Alzheimer's Disease and Aging Brain.Front Aging Neurosci2021
33206327Molecular Correlates of Hemorrhage and Edema Volumes Following Human Intracerebral Hemorrhage Implicate Inflammation, Autophagy, mRNA Splicing, and T Cell Receptor Signaling.Transl Stroke Res2021
30966854MicroRNA and their target mRNAs change expression in whole blood of patients after intracerebral hemorrhage.J Cereb Blood Flow Metab2020
33193047Alternative Splicing of Putative Stroke/Vascular Risk Factor Genes Expressed in Blood Following Ischemic Stroke Is Sexually Dimorphic and Cause-Specific.Front Neurol2020
33173895Multi-ancestry genetic study in 5,876 patients identifies an association between excitotoxic genes and early outcomes after acute ischemic stroke.medRxiv2020
32941979Mechanical injury and blood are drivers of spatial memory deficits after rapid intraventricular hemorrhage.Neurobiol Dis2020
32785988Genetic variation contributes to gene expression response in ischemic stroke: an eQTL study.Ann Clin Transl Neurol2020
31595394mRNA Expression Profiles from Whole Blood Associated with Vasospasm in Patients with Subarachnoid Hemorrhage.Neurocrit Care2020
29651704HDAC9 Polymorphism Alters Blood Gene Expression in Patients with Large Vessel Atherosclerotic Stroke.Transl Stroke Res2019
31436916Smoking affects gene expression in blood of patients with ischemic stroke.Ann Clin Transl Neurol2019
31510897Cancer-Related Ischemic Stroke Has a Distinct Blood mRNA Expression Profile.Stroke2019
30836997Inflammatory, regulatory, and autophagy co-expression modules and hub genes underlie the peripheral immune response to human intracerebral hemorrhage.J Neuroinflammation2019
29651892The intracerebral hemorrhage blood transcriptome in humans differs from the ischemic stroke and vascular risk factor control blood transcriptomes.J Cereb Blood Flow Metab2019
29708005MicroRNA-based therapeutics in central nervous system injuries.J Cereb Blood Flow Metab2018
30405345MicroRNA-122 Mimic Improves Stroke Outcomes and Indirectly Inhibits NOS2 After Middle Cerebral Artery Occlusion in Rats.Front Neurosci2018
29520228Lipopolysaccharide Associates with Amyloid Plaques, Neurons and Oligodendrocytes in Alzheimer's Disease Brain: A Review.Front Aging Neurosci2018
29408985Cleaved β-Actin May Contribute to DNA Fragmentation Following Very Brief Focal Cerebral Ischemia.J Neuropathol Exp Neurol2018
27624844Inhibition of Src family kinases improves cognitive function after intraventricular hemorrhage or intraventricular thrombin.J Cereb Blood Flow Metab2017
28477280Biomarkers of Acute Stroke Etiology (BASE) Study Methodology.Transl Stroke Res2017
28184278Possible sexually dimorphic role of miRNA and other sncRNA in ASD brain.Mol Autism2017
28947587Clinical Reasoning: A case of altered mental status, not otherwise specified.Neurology2017
27862943Blood transcriptomic comparison of individuals with and without autism spectrum disorder: A combined-samples mega-analysis.Am J Med Genet B Neuropsychiatr Genet2017
26973468Implications of MMP9 for Blood Brain Barrier Disruption and Hemorrhagic Transformation Following Ischemic Stroke.Front Cell Neurosci2016
26661204Elevating microRNA-122 in blood improves outcomes after temporary middle cerebral artery occlusion in rats.J Cereb Blood Flow Metab2016
27784773Leukocyte response is regulated by microRNA let7i in patients with acute ischemic stroke.Neurology2016
27784770Gram-negative bacterial molecules associate with Alzheimer disease pathology.Neurology2016
27834745Altered Expression of Long Noncoding RNAs in Blood After Ischemic Stroke and Proximity to Putative Stroke Risk Loci.Stroke2016
24526567Improving the translation of animal ischemic stroke studies to humans.Metab Brain Dis2015
26350727Specific Regional and Age-Related Small Noncoding RNA Expression Patterns Within Superior Temporal Gyrus of Typical Human Brains Are Less Distinct in Autism Brains.J Child Neurol2015
27858746MicroRNA and mRNA Expression Changes in Steroid Naïve and Steroid Treated DMD Patients.J Neuromuscul Dis2015
26146533Atypical miRNA expression in temporal cortex associated with dysregulation of immune, cell cycle, and other pathways in autism spectrum disorders.Mol Autism2015
25657186Biomarker panels in ischemic stroke.Stroke2015
25697841Myelin basic protein associates with AβPP, Aβ1-42, and amyloid plaques in cortex of Alzheimer's disease brain.J Alzheimers Dis2015
25790832Inflammation Combined with Ischemia Produces Myelin Injury and Plaque-Like Aggregates of Myelin, Amyloid-β and AβPP in Adult Rat Brain.J Alzheimers Dis2015
25806703Targeting neutrophils in ischemic stroke: translational insights from experimental studies.J Cereb Blood Flow Metab2015
24184979Autophagy in the brain of neonates following hypoxia-ischemia shows sex- and region-specific effects.Neuroscience2014
25036109Gene expression in peripheral immune cells following cardioembolic stroke is sexually dimorphic.PLoS One2014
25061082Modeling immunity and inflammation in stroke: differences between rodents and humans?Stroke2014
25084529Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome.PLoS One2014
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Collaborators

University of California at Davis, MIND Institute Biosciences Building Room 7
Co-authored papers 66
University of Maryland School of Medicine
Co-authored papers 28
University of California San Francisco
Co-authored papers 17
University of Cincinnati College of Medicine
Co-authored papers 12
University of North Carolina Health Sciences at Mountain Area Health Education Center
Co-authored papers 10
College of Medicine, University of Cincinnati
Co-authored papers 9
Cincinnati Children's Hospital Medical Center and the University of Cincinnati
Co-authored papers 8
Wake Forest School of Medicine
Co-authored papers 8
University of California Davis
Co-authored papers 7
Cincinnati Children's Hospital Medical Center
Co-authored papers 7
The MIND Institute, University of California davis
Co-authored papers 5
University of California san francisco
Co-authored papers 4
Cincinnati Children's Hospital Medical Center
Co-authored papers 4
University of California, Davis School of Medicine, United States MIND Institute
Co-authored papers 3
Department of Neurology University of California San Francisco CA.
Co-authored papers 2
University of Cincinnati Gardner Neuroscience Institute, University of Cincinnati
Co-authored papers 2
University of Alabama at Birmingham (UAB)
Co-authored papers 2
Vanderbilt University Medical Center
Co-authored papers 2
Co-authored papers 2
University of Cincinnati Medical Center
Co-authored papers 2
University of Cincinnati Gardner Neuroscience Institute
Co-authored papers 2
Center for Cerebrovascular Research
Co-authored papers 1
Loma Linda University
Co-authored papers 1
SUNY Upstate Medical University
Co-authored papers 1
Massachusetts General Hospital
Co-authored papers 1
Alpert Medical School of Brown University
Co-authored papers 1
Weill Cornel School of Medicine
Co-authored papers 1
SUNY Upstate Medical University
Co-authored papers 1
Meyer Cancer Center, Weill Cornell Medicine-NewYork Presbyterian Hospital
Co-authored papers 1
Vagelos College of Physicians and Surgeons (D.Y., Columbia University
Co-authored papers 1