Author details

Full Name

Roberta A Gottlieb

Affiliation

ORCID

Career Start Year

1983

Papers

209

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35220898	Autophagy deficiency abolishes liver mitochondrial DNA segregation.		2022
36044516	TBK1 and GABARAP family members suppress Coxsackievirus B infection by limiting viral production and promoting autophagic degradation of viral extracellular vesicles.	PLoS Pathogens	2022
35941013	Calcium, mitochondria and the initiation of acute pancreatitis.	Pancreatology	2022
35470068	Asporin, an extracellular matrix protein, is a beneficial regulator of cardiac remodeling.	Matrix Biology	2022
35598827	PACT establishes a posttranscriptional brake on mitochondrial biogenesis by promoting the maturation of miR-181c.	Journal of Biological Chemistry	2022
35091576	Depletion of mitochondrial methionine adenosyltransferase Î±1 triggers mitochondrial dysfunction in alcohol-associated liver disease.	Nat Commun	2022
35008865	Attenuation of Adverse Postinfarction Left Ventricular Remodeling with Empagliflozin Enhances Mitochondria-Linked Cellular Energetics and Mitochondrial Biogenesis.	International Journal of Molecular Sciences	2021
33544154	At the heart of mitochondrial quality control: many roads to the top.	Cellular and Molecular Life Sciences	2021
34331901	Hypothermia promotes mitochondrial elongation In cardiac cells via inhibition of Drp1.	Cryobiology	2021
33863814	Elevated Asparagine Biosynthesis Drives Brain Tumor Stem Cell Metabolic Plasticity and Resistance to Oxidative Stress.	Mol Cancer Res	2021
33361152	Recruitment of pro-IL-1Î± to mitochondrial cardiolipin, via shared LC3 binding domain, inhibits mitophagy and drives maximal NLRP3 activation.	Proc Natl Acad Sci U S A	2021
34403365	Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis.	JCI Insight	2021
34445425	Proteomics of Mouse Heart Ventricles Reveals Mitochondria and Metabolism as Major Targets of a Post-Infarction Short-Acting GLP1Ra-Therapy.	Int J Mol Sci	2021
34486814	Myocardial ultrastructure can augment genetic testing for sporadic dilated cardiomyopathy with initial heart failure.	ESC heart failure	2021
32499407	Parkin, an E3 ubiquitin ligase, enhances airway mitochondrial DNA release and inflammation.	Thorax	2020
32427925	Intermittent Use of a Short-Course Glucagon-like Peptide-1 Receptor Agonist Therapy Limits Adverse Cardiac Remodeling via Parkin-dependent Mitochondrial Turnover.	Scientific Reports	2020
32112488	Î² -adrenoceptor activation improves skeletal muscle autophagy in neurogenic myopathy.	FASEB Journal	2020
32234390	MitoPlex: A targeted multiple reaction monitoring assay for quantification of a curated set of mitochondrial proteins.	J Mol Cell Cardiol	2020
32390863	Minimal Invasive Pericardial Perfusion Model in Swine: A Translational Model for Cardiac Remodeling After Ischemia/Reperfusion Injury.	Frontiers in Physiology	2020
32762530	Sensing Protein Quality in Cardiac Myocytes p62 Triggers a Lysosomal Response.	Circulation Research	2020
32848877	Neurotropin Inhibits Lipid Accumulation by Maintaining Mitochondrial Function in Hepatocytes via AMPK Activation.	Frontiers in Physiology	2020
31292486	Myocardial hypothermia increases autophagic flux, mitochondrial mass and myocardial function after ischemia-reperfusion injury.	Scientific Reports	2019
31582142	Pushing the Heart Over a KLF(15).	Journal of the American College of Cardiology	2019
32039238	Decrease of Cardiac Parkin Protein in Obese Mice.	Frontiers in Cardiovascular Medicine	2019
31235522	Murine macrophage autophagy protects against alcohol-induced liver injury by degrading interferon regulatory factor 1 (IRF1) and removing damaged mitochondria.	Journal of Biological Chemistry	2019
31088290	Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling.	Antioxidants and Redox Signaling	2019
30871699	Intercepting the Lipid-Induced Integrated Stress Response Reduces Atherosclerosis.	Journal of the American College of Cardiology	2019
31077594	Methionine Adenosyltransferase Î±1 Is Targeted to the Mitochondrial Matrix and Interacts with Cytochrome P450 2E1 to Lower Its Expression.	Hepatology	2019
31401347	Matrix-guided control of mitochondrial function in cardiac myocytes.		2019
31398467	Simvastatin induces autophagic flux to restore cerulein-impaired phagosome-lysosome fusion in acute pancreatitis.		2019
30728329	Myocardial fibrosis after adrenergic stimulation as a long-term sequela in a mouse model of Kawasaki disease vasculitis.	JCI insight	2019
30829115	Autophagy plays a protective role against Trypanosoma cruzi infection in mice.	Virulence	2019
30712056	Retraction Note: Endocrine disruptors induce perturbations in endoplasmic reticulum and mitochondria of human pluripotent stem cell derivatives.	Nature Communications	2019
30711774	Coxsackievirus B infection induces the extracellular release of miR-590-5p, a proviral microRNA.	Virology	2019
29233845	Physiological Mitochondrial Fragmentation Is a Normal Cardiac Adaptation to Increased Energy Demand.	Circulation Research	2018
30223899	Sex differences in ischemic heart disease and heart failure biomarkers.	Biol Sex Differ	2018
30222143	Dynamic Proteomic and miRNA Analysis of Polysomes from Isolated Mouse Heart After Langendorff Perfusion.	J Vis Exp	2018
30449736	Oxidative muscles have better mitochondrial homeostasis than glycolytic muscles throughout life and maintain mitochondrial function during aging.	Aging	2018
30004239	Proteomics reveals Rictor as a noncanonical TGF-Î² signaling target during aneurysm progression in Marfan mice.	Am J Physiol Heart Circ Physiol	2018
30047926	Stromal epigenetic alterations drive metabolic and neuroendocrine prostate cancer reprogramming.	J Clin Invest	2018
29717261	Antagonizing CD105 enhances radiation sensitivity in prostate cancer.	Oncogene	2018
29478899	Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy.	Stem Cell Reports	2018
29520828	Periodontal disease and its connection to systemic biomarkers of cardiovascular disease in young American Indian/Alaskan natives.	J Periodontol	2018
29602772	Cutting Edge: Mitochondrial Assembly of the NLRP3 Inflammasome Complex Is Initiated at Priming.	Journal of Immunology	2018
29681516	Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses.		2018
28239650	Mitophagy and mitochondrial biogenesis in atrial tissue of patients undergoing heart surgery with cardiopulmonary bypass.	JCI insight	2017
28733449	Mitochondrial function in engineered cardiac tissues is regulated by extracellular matrix elasticity and tissue alignment.	American Journal of Physiology - Heart and Circulatory Physiology	2017
28911513	Delivering Instant Heat: Shocking the Heart.	Journal of the American College of Cardiology	2017
28598232	Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure.		2017
28679444	Erratum to: Hypercholesterolemia downregulates autophagy in the rat heart.	Lipids in Health and Disease	2017