Author details

Full Name

Brian C Leonard

Affiliation

ORCID

Career Start Year

1972

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36470430	The TGM2 inhibitor cysteamine hydrochloride does not impact corneal epithelial and stromal wound healing in vitro and in vivo.	Experimental Eye Research	2023
37134072	Oculosystemic pneumocystosis in 2 sibling Chihuahuas.		2023
37074694	Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs' Endothelial Corneal Dystrophy.	Invest Ophthalmol Vis Sci	2023
36806671	Effect of graphene-based nanomaterials on corneal wound healing in vitro.		2023
36786010	A comparative review of evaporative dry eye disease and meibomian gland dysfunction in dogs and humans.		2023
36575128	A review of diagnostic tests for qualitative and quantitative tear film deficiency in dogs.		2023
36478371	Identification of putative orthologs of clinically relevant antimicrobial peptides in the equine ocular surface and amniotic membrane.		2023
36156731	Normal Corneal Thickness and Endothelial Cell Density in Rhesus Macaques (Macaca mulatta).	Transl Vis Sci Technol	2022
36048012	Topical Ripasudil for the Treatment of Primary Corneal Endothelial Degeneration in Dogs.	Translational Vision Science and Technology	2022
35758026	Arap1 loss causes retinal pigment epithelium phagocytic dysfunction and subsequent photoreceptor death.	Dis Model Mech	2022
35722307	Antimicrobial Peptide Expression at the Ocular Surface and Their Therapeutic Use in the Treatment of Microbial Keratitis.	Frontiers in Microbiology	2022
35631569	Metallic Engineered Nanomaterials and Ocular Toxicity: A Current Perspective.	Pharmaceutics	2022
35346188	Multimodal ocular imaging of known and novel corneal stromal disorders in dogs.	BMC Veterinary Research	2022
35129590	Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms.	Invest Ophthalmol Vis Sci	2022
34971485	Canine endotheliitis: Clinical characteristics, advanced imaging features, and treatment.	Veterinary Ophthalmology	2022
36348026	Ocular morphologic traits in the American Cocker Spaniel may confer primary angle closure glaucoma susceptibility.	Sci Rep	2022
36291655	Andrographolide Inhibits Corneal Fibroblast to Myofibroblast Differentiation .	Biomolecules	2022
34184388	Correlations between clinical signs and corneal cytology in feline eosinophilic keratoconjunctivitis.	Veterinary Ophthalmology	2021
33420346	Biallelic UBE4A loss-of-function variants cause intellectual disability and global developmental delay.	Genet Med	2021
35559825	Transcorneal delivery of topically applied silver nanoparticles does not delay epithelial wound healing.	NanoImpact	2021
33220237	Differential effects of Hsp90 inhibition on corneal cells in vitro and in vivo.	Experimental Eye Research	2021
33140999	Subcutaneous administration of triamcinolone as part of the management of feline eosinophilic keratoconjunctivitis.	Journal of Feline Medicine and Surgery	2021
32947393	A Retrospective Study of Corneal Endothelial Dystrophy in Dogs (1991-2014).	Cornea	2021
34647480	Comparison of intraocular pressures estimated by rebound and applanation tonometry in dogs with lens instability: 66 cases (2012-2018).	Journal of the American Veterinary Medical Association	2021
34590914	Novel Lipids of the Rabbit Harderian Gland Improve Tear Stability in an Animal Model of Dry Eye Disease.	Journal of Ocular Pharmacology and Therapeutics	2021
34532411	Retinal degeneration in mice and humans with neuronal ceroid lipofuscinosis type 8.	Ann Transl Med	2021
34532408	Animal models of corneal endothelial dysfunction to facilitate development of novel therapies.	Annals of Translational Medicine (discontinued)	2021
32154443	Engineered metal oxide nanomaterials inhibit corneal epithelial wound healing and .	NanoImpact	2020
31339654	Acremonium and trichosporon fungal keratoconjunctivitis in a Leopard Gecko (Eublepharis macularius).	Veterinary Ophthalmology	2019
30854487	Erratum: Author Correction: Identification of genes required for eye development by high-throughput screening of mouse knockouts.	Commun Biol	2019
30471280	Biomechanical changes to Descemet's membrane precede endothelial cell loss in an early-onset murine model of Fuchs endothelial corneal dystrophy.	Experimental Eye Research	2019
29767565	Medical management of deep ulcerative keratitis in cats: 13 cases.	Journal of Feline Medicine and Surgery	2019
31881719	Stromal Collagen Arrangement Correlates with Stiffness of the Canine Cornea.	Bioengineering	2019
31369464	Comprehensive Clinical, Diagnostic, and Advanced Imaging Characterization of the Ocular Surface in Spontaneous Aqueous Deficient Dry Eye Disease in Dogs.	Cornea	2019
29631828	Unsuspected and misdiagnosed posterior uveal melanoma following enucleation and evisceration in Ottawa-Gatineau.	Canadian Journal of Ophthalmology	2018
29889638	A multidisciplinary, minimally invasive approach combining lacrimoscopy and fluoroscopically guided stenting for management of nasolacrimal apparatus obstruction in dogs.	Journal of the American Veterinary Medical Association	2018
29847629	A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice.	Invest Ophthalmol Vis Sci	2018
28324111	Arap1 Deficiency Causes Photoreceptor Degeneration in Mice.	Invest Ophthalmol Vis Sci	2017
28335619	Overexpression of the X-Linked Inhibitor of Apoptosis Protects Against Retinal Degeneration in a Feline Model of Retinal Detachment.	Human Gene Therapy	2017
27614208	Species variation and spatial differences in mucin expression from corneal epithelial cells.	Experimental Eye Research	2016
26427427	The Development of a Cat Model of Retinal Detachment and Re-attachment.	Advances in Experimental Medicine and Biology	2016
26747762	Effect of Stratification on Surface Properties of Corneal Epithelial Cells.	Investigative Ophthalmology and Visual Science	2015
24999101	Interfacial phenomena and the ocular surface.		2014
23774747	Visceral smooth muscle Î±-actin deficiency associated with chronic intestinal pseudo-obstruction in a Bengal cat (Felis catus x Prionailurus bengalensis).	Veterinary Pathology	2014
22261569	Activity, expression and genetic variation of canine Î²-defensin 103: a multifunctional antimicrobial peptide in the skin of domestic dogs.	J Innate Immun	2012
22798970	Controlled release of bevacizumab through nanospheres for extended treatment of age-related macular degeneration.	Open Ophthalmology Journal	2012
22409270	Antimicrobial peptides: agents of border protection for companion animals.	Veterinary Dermatology	2012
22322385	Bifidobacterium bifidum in a rat model of necrotizing enterocolitis: antimicrobial peptide and protein responses.	Pediatric Research	2012
21533281	Expression and activity of a novel cathelicidin from domestic cats.	PLoS ONE	2011
20149443	PEG-PLA microparticles for encapsulation and delivery of Tat-EGFP to retinal cells.	Biomaterials	2010