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Author Details

Patricia Baxter
Texas Children's Cancer Center, Baylor College of Medicine
2008
48
18
PMIDPaper TitleJournal TitlePublished Year
37415222Targeting GBM with an Oncolytic Picornavirus SVV-001 alone and in combination with fractionated Radiation in a Novel Panel of Orthotopic PDX models.J Transl Med2023
37526549Phase I trial of panobinostat in children with diffuse intrinsic pontine glioma: A report from the Pediatric Brain Tumor Consortium (PBTC-047).Neuro Oncol2023
35652336Phase II study of alisertib as a single agent for treating recurrent or progressive atypical teratoid/rhabdoid tumor.Neuro Oncol2023
36950217Phase II study of everolimus for recurrent or progressive pediatric ependymoma.Neurooncol Adv2023
34802040Evaluation of an EZH2 inhibitor in patient-derived orthotopic xenograft models of pediatric brain tumors alone and in combination with chemo- and radiation therapies.Lab Invest2022
35611273Phase I study of ribociclib and everolimus in children with newly diagnosed DIPG and high-grade glioma: A CONNECT pediatric neuro-oncology consortium report.Neurooncol Adv2022
36550163Publisher Correction: Epigenetic alterations of repeated relapses in patient-matched childhood ependymomas.Nat Commun2022
36335125Epigenetic Alterations of Repeated Relapses in Patient-matched Childhood Ependymomas.Nat Commun2022
35182954Synergistic anti-tumor efficacy of mutant isocitrate dehydrogenase 1 inhibitor SYC-435 with standard therapy in patient-derived xenograft mouse models of glioma.Transl Oncol2022
35307742Corrigendum to: LTBK-01. Updates On The Phase Ii And Re-treatment Study Of AZD6244 (Selumetinib) For Children With Recurrent Or Refractory Pediatric Low Grade Glioma: A Pediatric Brain Tumor Consortium (PBTC) Study.Neuro Oncol2022
34907396Retraction Note: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma.Nat Neurosci2022
33358190Corrigendum to "Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors" [Cancer Lett. 493 (2020) 197-206].Cancer Lett2021
33547201A Phase I and Surgical Study of Ribociclib and Everolimus in Children with Recurrent or Refractory Malignant Brain Tumors: A Pediatric Brain Tumor Consortium Study.Clin Cancer Res2021
33571520Neogenin is highly expressed in diffuse intrinsic pontine glioma and influences tumor invasion.Brain Res2021
33739455Early radiotherapy preserves vision in sporadic optic pathway glioma.Cancer2021
33631016A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study.Neuro Oncol2021
34719887Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma Invasion.Adv Sci (Weinh)2021
34133064Gadolinium is not necessary for surveillance MR imaging in children with chiasmatic-hypothalamic low-grade glioma.Pediatr Blood Cancer2021
34254296Overall survival and secondary malignant neoplasms in children receiving passively scattered proton or photon craniospinal irradiation for medulloblastoma.Cancer2021
33405376A phase I trial of the CDK 4/6 inhibitor palbociclib in pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC-042).Pediatr Blood Cancer2021
33025730Phase 1 study of pomalidomide in children with recurrent, refractory, and progressive central nervous system tumors: A Pediatric Brain Tumor Consortium trial.Pediatr Blood Cancer2021
32285998A phase 2 study of valproic acid and radiation, followed by maintenance valproic acid and bevacizumab in children with newly diagnosed diffuse intrinsic pontine glioma or high-grade glioma.Pediatr Blood Cancer2020
31842647Use of allopurinol to reduce hepatotoxicity from 6-mercaptopurine (6-MP) in patients with acute lymphoblastic leukemia (ALL).Leuk Lymphoma2020
32009149A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study.Neuro Oncol2020
33046443Functional Precision Medicine Identifies New Therapeutic Candidates for Medulloblastoma.Cancer Res2020
32891713Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors.Cancer Lett2020
32502459Response assessment in diffuse intrinsic pontine glioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) working group.Lancet Oncol2020
32241771Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium.AJNR Am J Neuroradiol2020
32424282Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma.Nat Neurosci2020
31151904Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial.Lancet Oncol2019
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
29090526A pediatric brain tumor consortium phase II trial of capecitabine rapidly disintegrating tablets with concomitant radiation therapy in children with newly diagnosed diffuse intrinsic pontine gliomas.Pediatr Blood Cancer2018
30355798Systems biology-based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma.Sci Transl Med2018
29463553Concurrent Inhibition of Neurosphere and Monolayer Cells of Pediatric Glioblastoma by Aurora A Inhibitor MLN8237 Predicted Survival Extension in PDOX Models.Clin Cancer Res2018
28825123Regulatory T cell subsets in patients with medulloblastoma at diagnosis and during standard irradiation and chemotherapy (PBTC N-11).Cancer Immunol Immunother2017
29152094Xenotransplantation of pediatric low grade gliomas confirms the enrichment of <i>BRAF</i> V600E mutation and preservation of <i>CDKN2A</i> deletion in a novel orthotopic xenograft mouse model of progressive pleomorphic xanthoastrocytoma.Oncotarget2017
26956263Preservation of KIT genotype in a novel pair of patient-derived orthotopic xenograft mouse models of metastatic pediatric CNS germinoma.J Neurooncol2016
25542650Long-term disease control and toxicity outcomes following surgery and intensity modulated radiation therapy (IMRT) in pediatric craniopharyngioma.Radiother Oncol2015
24470556A patient tumor-derived orthotopic xenograft mouse model replicating the group 3 supratentorial primitive neuroectodermal tumor in children.Neuro Oncol2014
25526772Silencing BMI1 eliminates tumor formation of pediatric glioma CD133+ cells not by affecting known targets but by down-regulating a novel set of core genes.Acta Neuropathol Commun2014
24460684Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion.Acta Neuropathol Commun2014
23658322Intravenous injection of oncolytic picornavirus SVV-001 prolongs animal survival in a panel of primary tumor-based orthotopic xenograft mouse models of pediatric glioma.Neuro Oncol2013
22459127Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma.Neuro Oncol2012
20563581Plasma and cerebrospinal fluid pharmacokinetics of MP470 in non-human primates.Cancer Chemother Pharmacol2011
21075780A single intravenous injection of oncolytic picornavirus SVV-001 eliminates medulloblastomas in primary tumor-based orthotopic xenograft mouse models.Neuro Oncol2011
20511191A clinically relevant orthotopic xenograft model of ependymoma that maintains the genomic signature of the primary tumor and preserves cancer stem cells in vivo.Neuro Oncol2010
19006222Acquired von Willebrand syndrome and Wilms tumor: not always benign.Pediatr Blood Cancer2009
18403755Direct orthotopic transplantation of fresh surgical specimen preserves CD133+ tumor cells in clinically relevant mouse models of medulloblastoma and glioma.Stem Cells2008
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Collaborators

Northwestern University
Co-authored papers 24
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 20
Xiangya Hospital of Central South University
Co-authored papers 17
Texas Children's Cancer Center, Baylor College of Medicine
Co-authored papers 14
University Hospital Regensburg
Co-authored papers 13
Texas Children's Cancer Center
Co-authored papers 13
Texas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine
Co-authored papers 12
Co-authored papers 11
Baylor College of Medicine
Co-authored papers 10
Co-authored papers 9
Co-authored papers 6
Children's National Hospital
Co-authored papers 6
National Cancer Institute
Co-authored papers 5
Co-authored papers 4
University of Pittsburgh School of Medicine
Co-authored papers 4
Children's National Hospital. Electronic address: .
Co-authored papers 4
Rady Children's Hospital San Diego.
Co-authored papers 4
Co-authored papers 4
Clinical Research Division, Fred Hutchinson Cancer Center
Co-authored papers 3
NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
Co-authored papers 3
The Hospital for Sick Children
Co-authored papers 3
University of California San Diego
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 3
St. Jude Children's Research Hospital
Co-authored papers 3