Author details

Full Name

Sara P Garcia

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37521788	Spacer Fidelity Assessments of Guide RNA by Top-Down Mass Spectrometry.		2023
37188660	GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy.	Nat Commun	2023
35982179	Single-cell analysis and functional characterization uncover the stem cell hierarchies and developmental origins of rhabdomyosarcoma.	Nat Cancer	2022
35967079	Genome-wide functional perturbation of human microsatellite repeats using engineered zinc finger transcription factors.	Cell Genom	2022
35544598	Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia.	Blood	2022
32606318	PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis.	Leukemia	2021
34012082	In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.	Nature	2021
33361335	The chromatin landscape of primary synovial sarcoma organoids is linked to specific epigenetic mechanisms and dependencies.	Life Sci Alliance	2020
32256978	hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells.	Oncotarget	2020
32001672	Two faces of bivalent domain regulate VEGFA responsiveness and angiogenesis.	Cell Death Dis	2020
30995674	Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors.	Nature	2019
31739806	Assessment of computational methods for the analysis of single-cell ATAC-seq data.	Genome Biol	2019
30573774	Molecularly distinct models of zebrafish Myc-induced B cell leukemia.	Leukemia	2019
31477922	CRISPR DNA base editors with reduced RNA off-target and self-editing activities.	Nat Biotechnol	2019
30670628	A dynamic and integrated epigenetic program at distal regions orchestrates transcriptional responses to VEGFA.	Genome Res	2019
29499154	Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma.	Cell Stem Cell	2018
30209390	In vivo CRISPR editing with no detectable genome-wide off-target mutations.	Nature	2018
30192230	<i>tp53</i> deficiency causes a wide tumor spectrum and increases embryonal rhabdomyosarcoma metastasis in zebrafish.	Elife	2018
29749398	Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia.	Leukemia	2018
28205406	Potency of Human Cardiosphere-Derived Cells from Patients with Ischemic Heart Disease Is Associated with Robust Vascular Supportive Ability.	Stem cells translational medicine	2017
27207878	Robust lineage reconstruction from high-dimensional single-cell data.	Nucleic Acids Res	2016
26375006	BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis.	Nature	2015
25258084	Transcriptional diversity during lineage commitment of human blood progenitors.	Science	2014
23872967	Compressing resequencing data with GReEn.	Methods in Molecular Biology	2013
25594089	A genomic distance for assembly comparison based on compressed maximal exact matches.	IEEE/ACM Transactions on Computational Biology and Bioinformatics	2013
24278218	DNA sequences at a glance.	PLoS ONE	2013
24231144	Inter-STOP symbol distances for the identification of coding regions.	Journal of integrative bioinformatics	2013
23831271	The breakdown of the word symmetry in the human genome.	Journal of Theoretical Biology	2013
22139935	GReEn: a tool for efficient compression of genome resequencing data.	Nucleic Acids Research	2012
22220210	Minimal absent words in four human genome assemblies.	PLoS ONE	2011
21386877	Minimal absent words in prokaryotic and eukaryotic genomes.	PLoS ONE	2011
21295040	Genome analysis with distance to the nearest dissimilar nucleotide.	Journal of Theoretical Biology	2011
21926435	Inter-dinucleotide distances in the human genome: an analysis of the whole-genome and protein-coding distributions.	Journal of integrative bioinformatics	2011
19759198	Genome analysis with inter-nucleotide distances.		2009
19426495	On finding minimal absent words.	BMC Bioinformatics	2009
16196759	Multivariate phase space reconstruction by nearest neighbor embedding with different time delays.	Phys Rev E Stat Nonlin Soft Matter Phys	2005
15903641	Nearest neighbor embedding with different time delays.	Phys Rev E Stat Nonlin Soft Matter Phys	2005