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Author Details

Jen Liou
2000
36
22
PMIDPaper TitleJournal TitlePublished Year
37390818Lysosomal LAMP proteins regulate lysosomal pH by direct inhibition of the TMEM175 channel.2023
36581712The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P<sub>2</sub> replenishment in response to TCR signaling during T cell development and survival.Nat Immunol2023
35020418Nir1 constitutively localizes at ER-PM junctions and promotes Nir2 recruitment for PIP homeostasis.Molecular Biology of the Cell2022
36551225Effects of Calcium Ions on the Antimicrobial Activity of Gramicidin A.2022
33973848The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains.Elife2021
37366370Sigma 1 Receptor, Cholesterol and Endoplasmic Reticulum Contact Sites.2021
33927055Dynamic remodeling of host membranes by self-organizing bacterial effectors.Science2021
32808593Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress.Elife2020
31879354Spatiotemporal regulation of NADP(H) phosphatase Nocturnin and its role in oxidative stress response.Proceedings of the National Academy of Sciences of the United States of America2020
31535977Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands.Elife2019
31799836Correction to Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α.Biochemistry2019
31184863Myristoylation-Dependent Palmitoylation of the Receptor Tyrosine Kinase Adaptor FRS2α.Biochemistry2019
30739879Recent insights into mammalian ER-PM junctions.Curr Opin Cell Biol2019
30790244Analysis of Phosphatidylinositol Transfer at ER-PM Junctions in Receptor-Stimulated Live Cells.Methods in Molecular Biology2019
30886058STING-mediated disruption of calcium homeostasis chronically activates ER stress and primes T cell death.J Exp Med2019
29563214EB1 binding restricts STIM1 translocation to ER-PM junctions and regulates store-operated Ca[2+] entry.J Cell Biol2018
29992992Structural analyses of FERM domain-mediated membrane localization of FARP1.Sci Rep2018
28600435RASSF4 controls SOCE and ER-PM junctions through regulation of PI(4,5)P<sub>2</sub>.J Cell Biol2017
28554772ER-plasma membrane junctions: Why and how do we study them?Biochim Biophys Acta Mol Cell Res2017
28954864Cortical actin contributes to spatial organization of ER-PM junctions.Mol Biol Cell2017
26924250Homeostatic regulation of the PI(4,5)P2-Ca(2+) signaling system at ER-PM junctions.2016
26025028Molecular mechanisms of inter-organelle ER-PM contact sites.Curr Opin Cell Biol2015
25887399Phosphatidylinositol 4,5-Bisphosphate Homeostasis Regulated by Nir2 and Nir3 Proteins at Endoplasmic Reticulum-Plasma Membrane Junctions.Journal of Biological Chemistry2015
25790092Unveiling physiological functions of extended synaptotagmins.Cell Cycle2015
25640239A micropeptide encoded by a putative long noncoding RNA regulates muscle performance.Cell2015
24183667Feedback regulation of receptor-induced Ca2+ signaling mediated by E-Syt1 and Nir2 at endoplasmic reticulum-plasma membrane junctions.Cell Reports2013
23906061Septins set the stage for Orai1 to bind STIM1 at ER-PM junctions.Developmental Cell2013
21441934STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development.Nat Immunol2011
18160041STIM2 is a feedback regulator that stabilizes basal cytosolic and endoplasmic reticulum Ca2+ levels.Cell2007
17517596Live-cell imaging reveals sequential oligomerization and local plasma membrane targeting of stromal interaction molecule 1 after Ca2+ store depletion.Proceedings of the National Academy of Sciences of the United States of America2007
17640392siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptake.2007
16005298STIM is a Ca2+ sensor essential for Ca2+-store-depletion-triggered Ca2+ influx.Current Biology2005
12478301Overview of the Alliance for Cellular Signaling.Nature2002
11278403Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB.J Biol Chem2001
11487585Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes.J Biol Chem2001
10795738HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1.Immunity2000
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