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Author Details

Jef D Boeke
Institute for Systems Genetics, NYU School of Medicine
1978
403
99
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37781588Genomic context sensitizes regulatory elements to genetic disruption.bioRxiv2024
37996532Author Correction: Longitudinal scRNA-seq analysis in mouse and human informs optimization of rapid mouse astrocyte differentiation protocols.Nat Neurosci2024
36821584Two differentially stable rDNA loci coexist on the same chromosome and form a single nucleolus.Proc Natl Acad Sci U S A2023
38020977Parallel laboratory evolution and rational debugging reveal genomic plasticity to <i>S. cerevisiae</i> synthetic chromosome XIV defects.Cell Genom2023
38020971Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics.Cell Genom2023
38020970Establishing chromosomal design-build-test-learn through a synthetic chromosome and its combinatorial reconfiguration.Cell Genom2023
38020968Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast.Cell Genom2023
37962556Humanization reveals pervasive incompatibility of yeast and human kinetochore components.G3 (Bethesda)2023
37914927Mouse genome rewriting and tailoring of three important disease loci.Nature2023
37488288Pig-to-human heart xenotransplantation in two recently deceased human recipients.Nat Med2023
37697111Longitudinal scRNA-seq analysis in mouse and human informs optimization of rapid mouse astrocyte differentiation protocols.Nat Neurosci2023
37990347Proceedings of the inaugural Dark Genome Symposium: November 2022.Mob DNA2023
37944511Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions.Cell2023
37781609Engineered transcription-associated Cas9 targeting in eukaryotic cells.bioRxiv2023
38036514Building a eukaryotic chromosome arm by de novo design and synthesis.Nat Commun2023
37326023CREEPY: CRISPR-mediated editing of synthetic episomes in yeast.Nucleic Acids Res2023
37114770Condensation of LINE-1 is critical for retrotransposition.Elife2023
37310664Transposon insertion profiling by sequencing (TIPseq) identifies novel LINE-1 insertions in human sperm.J Assist Reprod Genet2023
37339222Pervasive RNA folding is crucial for narnavirus genome maintenance.Proc Natl Acad Sci U S A2023
37205538Human macroH2A1 drives nucleosome dephasing and genome instability in histone-humanized yeast.bioRxiv2023
36651597DASH/Dam1 complex mutants stabilize ploidy in histone-humanized yeast by weakening kinetochore-microtubule attachments.EMBO J2023
36931273Synthetic regulatory genomics uncovers enhancer context dependence at the Sox2 locus.Mol Cell2023
36895643Safety by design: Biosafety and biosecurity in the age of synthetic genomics.iScience2023
35169076LINE-1 expression in cancer correlates with p53 mutation, copy number alteration, and S phase checkpoint.Proc Natl Acad Sci U S A2022
35771912Synthetic regulatory reconstitution reveals principles of mammalian <i>Hox</i> cluster regulation.Science2022
35584156Results of Two Cases of Pig-to-Human Kidney Xenotransplantation.N Engl J Med2022
35692632A conditional counterselectable <i>Piga</i> knockout in mouse embryonic stem cells for advanced genome writing applications.iScience2022
36108770Systems genomics in age-related macular degeneration.Exp Eye Res2022
36165439Resurrecting essential amino acid biosynthesis in mammalian cells.Elife2022
35983101Karyotype engineering reveals spatio-temporal control of replication firing and gene contacts.Cell Genom2022
35091469Sirt6 regulates lifespan in <i>Drosophila melanogaster</i>.Proc Natl Acad Sci U S A2022
35239377Transcriptional neighborhoods regulate transcript isoform lengths and expression levels.Science2022
33479126Regulation of the Dot1 histone H3K79 methyltransferase by histone H4K16 acetylation.Science2021
33852895Alternative splicing is a developmental switch for hTERT expression.Mol Cell2021
33742653De novo assembly and delivery to mouse cells of a 101 kb functional human gene.Genetics2021
33649239A versatile platform for locus-scale genome rewriting and verification.Proc Natl Acad Sci U S A2021
33591308Application of counter-selectable marker PIGA in engineering designer deletion cell lines and characterization of CRISPR deletion efficiency.Nucleic Acids Res2021
33563338RIP-seq reveals LINE-1 ORF1p association with p-body enriched mRNAs.Mob DNA2021
34936741Immune and Genome Engineering as the Future of Transplantable Tissue.N Engl J Med2021
34425899Unbiased proteomic mapping of the LINE-1 promoter using CRISPR Cas9.Mob DNA2021
34349292The role of retrotransposable elements in ageing and age-associated diseases.Nature2021
34347828EUAdb: A resource for COVID-19 test development and comparison.PLoS One2021
33441553Engineered dual selection for directed evolution of SpCas9 PAM specificity.Nat Commun2021
32569517Synthetic Genomes.Annu Rev Biochem2020
31745563Phylogenetic debugging of a complete human biosynthetic pathway transplanted into yeast.Nucleic Acids Res2020
32075555Human transposon insertion profiling by sequencing (TIPseq) to map LINE-1 insertions in single cells.Philos Trans R Soc Lond B Biol Sci2020
32042152BRCA1 and S phase DNA repair pathways restrict LINE-1 retrotransposition in human cells.Nat Struct Mol Biol2020
32042151Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication.Nat Struct Mol Biol2020
31978344Widespread Transcriptional Scanning in the Testis Modulates Gene Evolution Rates.Cell2020
33303586Genetic interaction mapping informs integrative structure determination of protein complexes.Science2020
  • 1 - 50 of 403

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Collaborators

Joel S Bader
Johns Hopkins University
Co-authored papers 43
David Feny??
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Co-authored papers 21
Junbiao Dai
Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences
Co-authored papers 21
Kun Yang
Co-authored papers 15
Sarah J Wheelan
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 12
Ran Brosh
Co-authored papers 10
Matthew T Maurano
Institute for Systems Genetics, NYU School of Medicine
Co-authored papers 9
Rafael A Irizarry
Dana-Farber Cancer Institute
Co-authored papers 9
Zuojian Tang
Co-authored papers 8
Shuangying Jiang
College of Life Sciences and Oceanography, Shenzhen University
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Huanming Yang
Experimental Research Center, China Academy of Chinese Medical Sciences
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Gregory J Cost
Metagenomi Inc., Pre-clinical
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Philip Hieter
University of British Columbia
Co-authored papers 7
Xuya Wang
Co-authored papers 6
Forrest A Spencer
Johns Hopkins University School of Medicine
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Donghui Li
Qilu University of Technology (Shandong Academy of Sciences)
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Philip A Cole
Brigham and Women's Hospital, Blavatnik Institute, Harvard Medical School
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Gennady V Merkulov
The Johns Hopkins University School of Medicine
Co-authored papers 5
Lorraine Pillus
University of California San Diego
Co-authored papers 4
Sarah Keegan
Institute for Systems Genetics, New York University Langone Medical Center
Co-authored papers 4
Yingming Zhao
Co-authored papers 4
Akhilesh Pandey
Co-authored papers 4
Oxana K Pickeral
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 4
Michael P Rout
The Rockefeller University
Co-authored papers 3
Andr?? M Ribeiro-Dos-Santos
Institute for Systems Genetics, NYU School of Medicine
Co-authored papers 3
Vera Gorbunova
University of Rochester
Co-authored papers 3
Marcus B Noyes
Co-authored papers 3
Robert J Cotter
Co-authored papers 3
Shelley L Berger
Penn Epigenetics Institute, Perelman School of Medicine
Co-authored papers 3
Francisco Martinez Murillo
Co-authored papers 3
Release 1.2