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Author Details
Full Name
Andreas Bracher
Affiliation
Max-Planck-Institute of Biochemistry
ORCID
Career Start Year
1995
Papers
100
H Index
43
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36520302
Nucleotide Exchange Factors for Hsp70 Molecular Chaperones: GrpE, Hsp110/Grp170, HspBP1/Sil1, and BAG Domain Proteins.
Subcell Biochem
2023
36325051
Ebola and Marburg virus VP35 coiled-coil validated as antiviral target by tripartite split-GFP complementation.
iScience
2022
35521968
The chaperone Clusterin in neurodegeneration-friend or foe?
Bioessays
2022
33039147
High-resolution structure and biophysical characterization of the nucleocapsid phosphoprotein dimerization domain from the Covid-19 severe acute respiratory syndrome coronavirus 2.
Biochem Biophys Res Commun
2021
33843131
Macrocyclic FKBP51 Ligands Define a Transient Binding Mode with Enhanced Selectivity.
Angew Chem Int Ed Engl
2021
34381050
The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model.
Nat Commun
2021
34820091
Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3.1] aza-amides.
Chem Sci
2021
34650037
The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends.
Nat Commun
2021
32339190
Structure and conformational cycle of a bacteriophage-encoded chaperonin.
PLoS One
2020
31800244
A Novel Decalin-Based Bicyclic Scaffold for FKBP51-Selective Ligands.
J Med Chem
2020
33153600
Reaction rate ambiguities for perturbed spectroscopic data: Theory and implementation.
Anal Chim Acta
2020
32979320
Dual Functions of a Rubisco Activase in Metabolic Repair and Recruitment to Carboxysomes.
Cell
2020
30675061
Rubisco condensate formation by CcmM in β-carboxysome biogenesis.
Nature
2019
30950829
Crystal structure of phosphoribulokinase from Synechococcus sp. strain PCC 6301.
Acta Crystallogr F Struct Biol Commun
2019
30876804
Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2.
Mol Cell
2019
30482729
Structures of Ebola and Reston Virus VP35 Oligomerization Domains and Comparative Biophysical Characterization in All Ebolavirus Species.
Structure
2019
29336887
GroEL Ring Separation and Exchange in the Chaperonin Reaction.
Cell
2018
29578710
Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins.
J Med Chem
2018
28580920
Crystal structure of the Thermoplasma acidophilum protein Ta1207.
Acta Crystallogr F Struct Biol Commun
2017
28125284
Biogenesis and Metabolic Maintenance of Rubisco.
Annu Rev Plant Biol
2017
29217567
Plant RuBisCo assembly in <i>E. coli</i> with five chloroplast chaperones including BSD2.
Science
2017
28803776
Mechanism of Enzyme Repair by the AAA<sup>+</sup> Chaperone Rubisco Activase.
Mol Cell
2017
26727489
Structure of human heat-shock transcription factor 1 in complex with DNA.
Nat Struct Mol Biol
2016
26422689
The GroEL-GroES Chaperonin Machine: A Nano-Cage for Protein Folding.
Trends Biochem Sci
2016
26954324
Rapid, Structure-Based Exploration of Pipecolic Acid Amides as Novel Selective Antagonists of the FK506-Binding Protein 51.
J Med Chem
2016
25487014
GrpE, Hsp110/Grp170, HspBP1/Sil1 and BAG domain proteins: nucleotide exchange factors for Hsp70 molecular chaperones.
Subcell Biochem
2015
26305355
Structural Analysis of the Rubisco-Assembly Chaperone RbcX-II from Chlamydomonas reinhardtii.
PLoS One
2015
26419422
Structure-Affinity Relationship Analysis of Selective FKBP51 Ligands.
J Med Chem
2015
27246049
Degradation of potent Rubisco inhibitor by selective sugar phosphatase.
Nat Plants
2015
26913285
The nucleotide exchange factors of Hsp70 molecular chaperones.
Front Mol Biosci
2015
26237510
Structure and mechanism of the Rubisco-assembly chaperone Raf1.
Nat Struct Mol Biol
2015
25412894
Rational design and asymmetric synthesis of potent and neurotrophic ligands for FK506-binding proteins (FKBPs).
Angew Chem Int Ed Engl
2015
25436518
Selective inhibitors of the FK506-binding protein 51 by induced fit.
Nat Chem Biol
2015
23543331
Maintaining photosynthetic CO2 fixation via protein remodelling: the Rubisco activases.
Photosynth Res
2014
25286062
Stereoselective construction of the 5-hydroxy diazabicyclo[4.3.1]decane-2-one scaffold, a privileged motif for FK506-binding proteins.
Org Lett
2014
25200683
A combined IR/IR and IR/UV spectroscopy study on the proton transfer coordinate of isolated 3-hydroxychromone in the electronic ground and excited state.
Phys Chem Chem Phys
2014
24813614
GroEL/ES chaperonin modulates the mechanism and accelerates the rate of TIM-barrel domain folding.
Cell
2014
24516147
Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11.
Proc Natl Acad Sci U S A
2014
24650728
Thermostatted micro-reactor NMR probe head for monitoring fast reactions.
J Magn Reson
2014
22951723
Epidermal growth factor facilitates melanoma lymph node metastasis by influencing tumor lymphangiogenesis.
J Invest Dermatol
2013
23933011
Crystal structures of the free and ligand-bound FK1-FK2 domain segment of FKBP52 reveal a flexible inter-domain hinge.
J Mol Biol
2013
23647266
Increasing the efficiency of ligands for FK506-binding protein 51 by conformational control.
J Med Chem
2013
23746257
Molecular chaperone functions in protein folding and proteostasis.
Annu Rev Biochem
2013
23812373
Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle.
Nat Struct Mol Biol
2013
23190889
A c-kit mutation in exon 18 in familial mastocytosis.
J Invest Dermatol
2013
23358420
Large FK506-binding proteins shape the pharmacology of rapamycin.
Mol Cell Biol
2013
22187461
The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes together.
Proc Natl Acad Sci U S A
2012
23197838
Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT.
Proc Natl Acad Sci U S A
2012
22984071
Structural probing of a protein phosphatase 2A network by chemical cross-linking and mass spectrometry.
Science
2012
22503819
The molecular architecture of the eukaryotic chaperonin TRiC/CCT.
Structure
2012
1 - 50 of 100
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row(s) 1 - 30 of 30
Collaborators
Istv??n Nagy
Institute of Biochemistry, HUN-REN Biological Research Centre
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7
Wolfgang Baumeister
Max Planck Institute of Biochemistry
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5
Stephen F Doran
Co-authored papers
4
Sadis Matalon
Co-authored papers
4
Ganesh Pathare
Institute of Anatomy, University of Zurich
Co-authored papers
3
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Max Planck Institute of Biochemistry
Co-authored papers
3
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ETH Zurich
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2
Agnes Hubert
Institute of Biochemistry and Molecular Biology, Semmelweis University
Co-authored papers
2
Friedrich F??rster
Utrecht University
Co-authored papers
2
Stephan Nickell
Max Planck Institute of Biochemistry
Co-authored papers
2
Thomas Walzthoeni
Institute for Computational Biology
Co-authored papers
2
Stefan Bohn
Technical University Darmstadt
Co-authored papers
2
Ruedi Aebersold
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers
2
Taiki Nishioka
MicroBiopharm Japan Co. Ltd.
Co-authored papers
1
Yujin E Kim
Co-authored papers
1
Roland Beckmann
University of Munich
Co-authored papers
1
Nenad Ban
Institute of Molecular Biology and Biophysics, ETH Zurich
Co-authored papers
1
Judith Frydman
Stanford University
Co-authored papers
1
Stephan Becker
Institute of Virology, Philipps University Marburg
Co-authored papers
1
Steven J Ludtke
Baylor College of Medicine
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1
Abdullah Kahraman
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1
Martin Zacharias
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1
Florian Beck
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1
Pia Unverdorben
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