Skip to Main Content

Author Details

Fraser Soares
Princess Margaret Cancer Centre, University Health Network
2009
33
25
PMIDPaper TitleJournal TitlePublished Year
36928661Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.Nucleic Acids Res2023
36997534MYC reshapes CTCF-mediated chromatin architecture in prostate cancer.Nat Commun2023
34968454N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer.Gastroenterology2022
35752171Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1.Mol Cell2022
35154288The Basis and Promise of Programmable RNA Editing and Modification.Front Genet2022
33417860Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy.Cell2021
33741908CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer.Nat Commun2021
34621019CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer.Oncogene2021
33217448RNA N<sup>6</sup>-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m<sup>6</sup>A-GLUT1-mTORC1 Axis and Is a Therapeutic Target.Gastroenterology2021
33420488Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression.Nat Cell Biol2021
33270841CRISPR screen identifies genes that sensitize AML cells to double-negative T-cell therapy.Blood2021
31974375Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer.Nat Commun2020
30655535ONECUT2 is a driver of neuroendocrine prostate cancer.Nat Commun2019
30191480The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1.Mol Cell Biochem2019
30735634Widespread and Functional RNA Circularization in Localized Prostate Cancer.Cell2019
30033362Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.Cell2018
30212448Refined RIP-seq protocol for epitranscriptome analysis with low input materials.PLoS Biol2018
27885842Crucial role of noncoding RNA in driving prostate cancer development and progression.Epigenomics2017
28289232Transcriptional landscape of the human cell cycle.Proc Natl Acad Sci U S A2017
29754555Noncoding RNA for personalized prostate cancer treatment: utilizing the 'dark matters' of the genome.Per Med2017
28916652LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression.Cancer Res2017
27526323Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer.Nat Genet2016
25540141NOD-like receptors: versatile cytosolic sentinels.Physiol Rev2015
24394413Peptidoglycan LD-carboxypeptidase Pgp2 influences Campylobacter jejuni helical cell shape and pathogenic properties and provides the substrate for the DL-carboxypeptidase Pgp1.J Biol Chem2014
24867956The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis.J Biol Chem2014
23212541NLRX1 does not inhibit MAVS-dependent antiviral signalling.Innate Immun2013
22718770Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3.J Biol Chem2012
22704617Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program.Cell Host Microbe2012
21799518Mitochondria in innate immunity.EMBO Rep2011
19898471Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry.Nat Immunol2010
20959452Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1.J Biol Chem2010
19218084Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells.Cell Host Microbe2009
19692591An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix.J Cell Sci2009
  • 1 - 33 of 33

Recommended Authors

Sanford Burnham Prebys Medical Discovery Institute
Career Start Year 2019
Number of shared co-authors 0
The University of Texas Southwestern Medical Center
Career Start Year 2016
Number of shared co-authors 3
The Institute for Genomic Medicine, Nationwide Children's Hospital
Career Start Year 2015
Number of shared co-authors 0
Cancer Science Institute of Singapore, National University of Singapore
Career Start Year 2015
Number of shared co-authors 0
Leiden University Medical Center
Career Start Year 2014
Number of shared co-authors 1
Weill Cornell Medical College.
Career Start Year 2013
Number of shared co-authors 8
USC Libraries Bioinformatic Services of the University of Southern California
Career Start Year 2012
Number of shared co-authors 2
McDermott Center for Human Growth and Development.
Career Start Year 2010
Number of shared co-authors 3
Nottingham Trent University
Career Start Year 2010
Number of shared co-authors 0
University of California irvine
Career Start Year 2009
Number of shared co-authors 0
The Francis Crick Institute
Career Start Year 2008
Number of shared co-authors 0
Yale School of Medicine
Career Start Year 2008
Number of shared co-authors 0
Arc Institute
Career Start Year 2007
Number of shared co-authors 12
Institute of Biomedical Science and Children's Hospital, Fudan University
Career Start Year 2006
Number of shared co-authors 0
Boston Children's Hospital
Career Start Year 2006
Number of shared co-authors 0
The University of Texas MD Anderson Cancer Center
Career Start Year 2006
Number of shared co-authors 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 2005
Number of shared co-authors 0
University of Science and Technology of China
Career Start Year 2005
Number of shared co-authors 1
University Hospital Bonn
Career Start Year 2004
Number of shared co-authors 1
Michigan State University College of Human Medicine
Career Start Year 2004
Number of shared co-authors 0
University of Tennessee Health Science Center
Career Start Year 2004
Number of shared co-authors 1
The Wistar Institute
Career Start Year 2003
Number of shared co-authors 1
Spanish National Cancer Research Centre-CNIO
Career Start Year 2002
Number of shared co-authors 0
Texas A&M University School of Medicine
Career Start Year 2001
Number of shared co-authors 0
Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Career Start Year 2001
Number of shared co-authors 4
University of Alabama at Birmingham
Career Start Year 2000
Number of shared co-authors 0
HudsonAlpha Institute for Biotechnology
Career Start Year 1999
Number of shared co-authors 1
The Ohio State University
Career Start Year 1997
Number of shared co-authors 1
Stanford University Medical Center
Career Start Year 1997
Number of shared co-authors 1
Broad Institute of MIT and Harvard
Career Start Year 1989
Number of shared co-authors 2

Collaborators

Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 20
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 12
the Second Hospital, Cheeloo College of Medicine, Shandong University
Co-authored papers 10
School of Public Health, Sun Yat-sen University
Co-authored papers 10
University of California los angeles
Co-authored papers 8
College of Life Science, Hunan Normal University
Co-authored papers 7
Princess Margaret Cancer Center/University Health Network
Co-authored papers 7
UCSF Medical Center-Mount Zion
Co-authored papers 6
University Health Network, University of Toronto
Co-authored papers 6
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 5
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 4
Princess Margaret Cancer Research Centre
Co-authored papers 4
Princess Margaret Cancer Center/University Health Network
Co-authored papers 4
University of British Columbia
Co-authored papers 4
University of Toronto
Co-authored papers 4
Princess Margaret Cancer Research Centre
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Princess Margaret Cancer Centre/University Health Network
Co-authored papers 3
University Health Network, University of Toronto
Co-authored papers 3
China University of Mining and Technology
Co-authored papers 3
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2
University of Toronto, Princess Margaret Cancer Centre
Co-authored papers 2
Princess Margaret Cancer Center, University Health Network, University of Toronto
Co-authored papers 2
Princess Margaret Cancer Center, University Health Network
Co-authored papers 2
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Royal North Shore Hospital
Co-authored papers 2
Ontario Institute for Cancer Research
Co-authored papers 2
German Cancer Research Center (DKFZ) & National Center for Tumor Diseases (NCT)
Co-authored papers 2
Institute of Tissue Banking and Biomaterial Research
Co-authored papers 2