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Author Details
Full Name
Fraser Soares
Affiliation
Princess Margaret Cancer Centre, University Health Network
ORCID
Career Start Year
2009
Papers
33
H Index
25
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36928661
Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.
Nucleic Acids Res
2023
36997534
MYC reshapes CTCF-mediated chromatin architecture in prostate cancer.
Nat Commun
2023
34968454
N6-Methyladenosine Reader YTHDF1 Promotes ARHGEF2 Translation and RhoA Signaling in Colorectal Cancer.
Gastroenterology
2022
35752171
Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1.
Mol Cell
2022
35154288
The Basis and Promise of Programmable RNA Editing and Modification.
Front Genet
2022
33417860
Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive Chemotherapy.
Cell
2021
33741908
CRISPRi screens reveal a DNA methylation-mediated 3D genome dependent causal mechanism in prostate cancer.
Nat Commun
2021
34621019
CRISPR screens identify cholesterol biosynthesis as a therapeutic target on stemness and drug resistance of colon cancer.
Oncogene
2021
33217448
RNA N<sup>6</sup>-Methyladenosine Methyltransferase METTL3 Facilitates Colorectal Cancer by Activating the m<sup>6</sup>A-GLUT1-mTORC1 Axis and Is a Therapeutic Target.
Gastroenterology
2021
33420488
Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression.
Nat Cell Biol
2021
33270841
CRISPR screen identifies genes that sensitize AML cells to double-negative T-cell therapy.
Blood
2021
31974375
Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer.
Nat Commun
2020
30655535
ONECUT2 is a driver of neuroendocrine prostate cancer.
Nat Commun
2019
30191480
The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1.
Mol Cell Biochem
2019
30735634
Widespread and Functional RNA Circularization in Localized Prostate Cancer.
Cell
2019
30033362
Risk SNP-Mediated Promoter-Enhancer Switching Drives Prostate Cancer through lncRNA PCAT19.
Cell
2018
30212448
Refined RIP-seq protocol for epitranscriptome analysis with low input materials.
PLoS Biol
2018
27885842
Crucial role of noncoding RNA in driving prostate cancer development and progression.
Epigenomics
2017
28289232
Transcriptional landscape of the human cell cycle.
Proc Natl Acad Sci U S A
2017
29754555
Noncoding RNA for personalized prostate cancer treatment: utilizing the 'dark matters' of the genome.
Per Med
2017
28916652
LSD1-Mediated Epigenetic Reprogramming Drives CENPE Expression and Prostate Cancer Progression.
Cancer Res
2017
27526323
Modulation of long noncoding RNAs by risk SNPs underlying genetic predispositions to prostate cancer.
Nat Genet
2016
25540141
NOD-like receptors: versatile cytosolic sentinels.
Physiol Rev
2015
24394413
Peptidoglycan LD-carboxypeptidase Pgp2 influences Campylobacter jejuni helical cell shape and pathogenic properties and provides the substrate for the DL-carboxypeptidase Pgp1.
J Biol Chem
2014
24867956
The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis.
J Biol Chem
2014
23212541
NLRX1 does not inhibit MAVS-dependent antiviral signalling.
Innate Immun
2013
22718770
Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3.
J Biol Chem
2012
22704617
Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program.
Cell Host Microbe
2012
21799518
Mitochondria in innate immunity.
EMBO Rep
2011
19898471
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry.
Nat Immunol
2010
20959452
Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1.
J Biol Chem
2010
19218084
Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells.
Cell Host Microbe
2009
19692591
An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix.
J Cell Sci
2009
1 - 33 of 33
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Michael Fraser
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University of British Columbia
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Stanley Zhou
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Trevor J Pugh
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Xin Xu
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Ming-Sound Tsao
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