Skip to Main Content

Author Details

Andrew D Wells
Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia
1996
100
46
PMIDPaper TitleJournal TitlePublished Year
36608130Variant-to-gene mapping followed by cross-species genetic screening identifies GPI-anchor biosynthesis as a regulator of sleep.Sci Adv2023
35654975A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation.Nat Genet2022
35537191Variant-to-gene-mapping analyses reveal a role for pancreatic islet cells in conferring genetic susceptibility to sleep-related traits.Sleep2022
33069917Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease.Cell Mol Gastroenterol Hepatol2021
335452323D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders.Prog Neurobiol2021
34405268Restriction enzyme selection dictates detection range sensitivity in chromatin conformation capture-based variant-to-gene mapping approaches.Hum Genet2021
34799566Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits.Nat Commun2021
34532616CRISPR-Cas9-Mediated Genome Editing Confirms <i>EPDR1</i> as an Effector Gene at the BMD GWAS-Implicated '<i>STARD3NL</i>' Locus.JBMR Plus2021
33936046Variant to Gene Mapping to Discover New Targets for Immune Tolerance.Front Immunol2021
34343493A UVB-responsive common variant at chromosome band 7p21.1 confers tanning response and melanoma risk via regulation of the aryl hydrocarbon receptor, AHR.Am J Hum Genet2021
33951726Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.J Exp Med2021
33459256Biological constraints on GWAS SNPs at suggestive significance thresholds reveal additional BMI loci.Elife2021
33397451Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual.Genome Biol2021
32535942Canonical Notch signaling is required for bone morphogenetic protein-mediated human osteoblast differentiation.Stem Cells2020
31993419Diversity and Emerging Roles of Enhancer RNA in Regulation of Gene Expression and Cell Fate.Front Cell Dev Biol2020
31953354IL-1 Transcriptional Responses to Lipopolysaccharides Are Regulated by a Complex of RNA Binding Proteins.J Immunol2020
32797243Next steps in the identification of gene targets for type 1 diabetes.Diabetologia2020
32620744Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells.Nat Commun2020
32561546Collapse of the hepatic gene regulatory network in the absence of FoxA factors.Genes Dev2020
30890710Genome-scale Capture C promoter interactions implicate effector genes at GWAS loci for bone mineral density.Nat Commun2019
31264971T follicular helper cells in human efferent lymph retain lymphoid characteristics.J Clin Invest2019
29150566The Loss of TET2 Promotes CD8<sup>+</sup> T Cell Memory Differentiation.J Immunol2018
30392958Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.Cell2018
29797095Leveraging epigenomics and contactomics data to investigate SNP pairs in GWAS.Hum Genet2018
28580955Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease.Nat Commun2017
28369050Antagonism of B cell enhancer networks by STAT5 drives leukemia and poor patient survival.Nat Immunol2017
29056226A Dementia-Associated Risk Variant near TMEM106B Alters Chromatin Architecture and Gene Expression.Am J Hum Genet2017
27539148The type 2 diabetes presumed causal variant within TCF7L2 resides in an element that controls the expression of ACSL5.Diabetologia2016
27695003Foxp3 and Toll-like receptor signaling balance T<sub>reg</sub> cell anabolic metabolism for suppression.Nat Immunol2016
25567984DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.Nucleic Acids Res2015
26351138Long-Range Transcriptional Control of the Il2 Gene by an Intergenic Enhancer.Mol Cell Biol2015
24337390A ChIP-seq-defined genome-wide map of MEF2C binding reveals inflammatory pathways associated with its role in bone density determination.Calcif Tissue Int2014
25469308Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data.BMJ Open Diabetes Res Care2014
25074018Regulatory T cells suppress CD4+ T cells through NFAT-dependent transcriptional mechanisms.EMBO Rep2014
24778448Ikaros imposes a barrier to CD8+ T cell differentiation by restricting autocrine IL-2 production.J Immunol2014
24878043Genome-wide analyses of ChIP-Seq derived FOXA2 DNA occupancy in liver points to genetic networks underpinning multiple complex traits.J Clin Endocrinol Metab2014
24614758Regulation of T cell differentiation and alloimmunity by the cyclin-dependent kinase inhibitor p18ink4c.PLoS One2014
24603166New roles for cyclin-dependent kinases in T cell biology: linking cell division and differentiation.Nat Rev Immunol2014
23979593Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.Mol Cell Biol2013
23853094Foxp3 protein stability is regulated by cyclin-dependent kinase 2.J Biol Chem2013
22584578De novo DNA methylation is required to restrict T helper lineage plasticity.J Biol Chem2012
23136201Cyclin-dependent kinase 2 controls peripheral immune tolerance.J Immunol2012
22813742Structural and biological features of FOXP3 dimerization relevant to regulatory T cell function.Cell Rep2012
22665476Conserved intergenic elements and DNA methylation cooperate to regulate transcription at the il17 locus.J Biol Chem2012
20102680Mutiny on the Boun-T: controlling dangerous T cells through anergy.Discov Med2010
19923223Ikaros silences T-bet expression and interferon-gamma production during T helper 2 differentiation.J Biol Chem2010
19117830Foxp3 processing by proprotein convertases and control of regulatory T cell function.J Biol Chem2009
19564342FOXP3 inhibits activation-induced NFAT2 expression in T cells thereby limiting effector cytokine expression.J Immunol2009
19494254New insights into the molecular basis of T cell anergy: anergy factors, avoidance sensors, and epigenetic imprinting.J Immunol2009
18606637Cutting edge: chromatin remodeling as a molecular basis for the enhanced functionality of memory CD8 T cells.J Immunol2008
  • 1 - 50 of 100

Recommended Authors

Xiuyuan Sun
Peking University
Career Start Year 2009
Number of shared co-authors 0
Ansuman T Satpathy
Stanford University
Career Start Year 2005
Number of shared co-authors 1
Ye Zheng
Salk Institute for Biological Studies
Career Start Year 2001
Number of shared co-authors 2
Martin Prlic
Fred Hutchinson Cancer Research Center
Career Start Year 2001
Number of shared co-authors 0
Dorian LaTocha
Knight Cancer Institute, Oregon Health & Science University
Career Start Year 2000
Number of shared co-authors 1
Evan F Lind
Oregon Health & Science University
Career Start Year 1999
Number of shared co-authors 0
John T Chang
University of California San Diego
Career Start Year 1999
Number of shared co-authors 0
Fran??ois Van Laethem
National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 0
Jane H Buckner
Center for Translational Immunology, Benaroya Research Institute at Virginia Mason
Career Start Year 1995
Number of shared co-authors 0
Francesca Fallarino
University of Perugia
Career Start Year 1995
Number of shared co-authors 0
Alexander Tarakhovsky
The Rockefeller University
Career Start Year 1994
Number of shared co-authors 0
Qi Wu
University of Michigan Medical School
Career Start Year 1989
Number of shared co-authors 0
Clare Baecher-Allan
Brigham and Women's Hospital, Harvard Medical School
Career Start Year 1988
Number of shared co-authors 0
Casey T Weaver
University of Alabama at Birmingham
Career Start Year 1986
Number of shared co-authors 0
David L Wiest
Fox Chase Cancer Center
Career Start Year 1986
Number of shared co-authors 0
John J O'Shea
National Institute of Arthritis, National Institutes of Health
Career Start Year 1984
Number of shared co-authors 1
Frances T Hakim
National Cancer Institute
Career Start Year 1984
Number of shared co-authors 0
Anjana Rao
La Jolla Institute for Immunology
Career Start Year 1983
Number of shared co-authors 0
Penelope A Morel
University of Pittsburgh
Career Start Year 1982
Number of shared co-authors 1
Shimon Sakaguchi
Institute for Frontier Medical Sciences, Kyoto University
Career Start Year 1981
Number of shared co-authors 1
Lionel Feigenbaum
Science Applications International Corporation/Frederick
Career Start Year 1981
Number of shared co-authors 2
Rafick-Pierre Sekaly
Pathology Advanced Translational Research Unit, Emory University School of Medicine
Career Start Year 1981
Number of shared co-authors 2
Carl H June
University of Pennsylvania Department of Pathology & Laboratory Medicine
Career Start Year 1978
Number of shared co-authors 2
Peter S Linsley
8Benaroya Research Institute
Career Start Year 1978
Number of shared co-authors 0
Ronald E Gress
National Cancer Institute, National Institutes of Health
Career Start Year 1977
Number of shared co-authors 0
Arthur Weiss
University of California san francisco
Career Start Year 1972
Number of shared co-authors 2
Ronald N Germain
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Career Start Year 1971
Number of shared co-authors 2
Tak W Mak
Princess Margaret Cancer Centre, University Health Network
Career Start Year 1970
Number of shared co-authors 0
Shigeo Koyasu
RIKEN Center for Integrative Medical Sciences (IMS)
Career Start Year 1966
Number of shared co-authors 0
David W Scott
University of British Columbia
Career Start Year 1965
Number of shared co-authors 0

Collaborators

Struan F A Grant
Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia
Co-authored papers 24
Matthew E Johnson
Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia
Co-authored papers 20
Alessandra Chesi
Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia
Co-authored papers 16
Sumei Lu
China National Center for Biotechnology Development
Co-authored papers 10
James A Pippin
Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia
Co-authored papers 10
Matthew C Pahl
Center for Spatial and Functional Genomics, The Children's Hospital of Philadelphia
Co-authored papers 9
Michelle E Leonard
The Children's Hospital of Philadelphia
Co-authored papers 9
Elisabetta Manduchi
Center for Spatial and Functional Genomics, Children's Hospital of Philadelphia
Co-authored papers 8
Kurt D Hankenson
University of Michigan School of Medicine ann arbor
Co-authored papers 6
Yadav Wagley
Department of Orthopedic Surgery University of Michigan Medical School Ann Arbor
Co-authored papers 5
Diana L Cousminer
Children's Hospital of Philadelphia
Co-authored papers 5
Klaus H Kaestner
Department of Genetics and Institute for Diabetes, University of Pennsylvania
Co-authored papers 4
Benjamin F Voight
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 3
Stephen S Rich
Co-authored papers 2
Christopher D Brown
Co-authored papers 2
Hakon Hakonarson
The Center for Applied Genomics, Children's Hospital of Philadelphia
Co-authored papers 2
Jonathan Schug
University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
Aguirre A de Cubas
Co-authored papers 2
Hamid Band
University of Nebraska Medical Center
Co-authored papers 2
Gerald Wertheim
Co-authored papers 2
Jason W Locasale
Duke University
Co-authored papers 2
Nicholas P Restifo
National Cancer Institute, National Institutes of Health (NIH)
Co-authored papers 1
Aris Baras
Co-authored papers 1
Shana E McCormack
The Children's Hospital of Philadelphia Division of Endocrinology and Diabetes
Co-authored papers 1
Luca A Lotta
Co-authored papers 1
Kyong-Mi Chang
Corporal Michael J Crescenz VA Medical Center
Co-authored papers 1
Arun J Sanyal
Virginia Commonwealth University
Co-authored papers 1
Scott L DuVall
University of Utah
Co-authored papers 1
Derek Klarin
Co-authored papers 1
Stephen J Chanock
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Release 1.2