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Author Details
Full Name
Ruth M Ruprecht
Affiliation
University of Texas San Antonio
ORCID
Career Start Year
1971
Papers
202
H Index
47
Expertise
CM4AI Collaborator
Sarah J Ratcliffe (CM4AI)
PMID
Paper Title
Journal Title
Published Year
37613382
Elucidating Vaccine Trafficking Mechanisms using Multimodal Imaging.
Microsc Microanal
2023
35273592
Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges.
Front Immunol
2022
35645210
Antibody Light Chains: Key to Increased Monoclonal Antibody Yields in Expi293 Cells?
Antibodies (Basel)
2022
35857825
Intranasal vaccination with lipid-conjugated immunogens promotes antigen transmucosal uptake to drive mucosal and systemic immunity.
Sci Transl Med
2022
33385332
Phage Display-Directed Discovery of LEDGF/p75 Binding Cyclic Peptide Inhibitors of HIV Replication.
Mol Ther
2021
33658998
Modified Adenovirus Prime-Protein Boost Clade C HIV Vaccine Strategy Results in Reduced Viral DNA in Blood and Tissues Following Tier 2 SHIV Challenge.
Front Immunol
2021
34860581
A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.
Sci Immunol
2021
34793582
Localization of infection in neonatal rhesus macaques after oral viral challenge.
PLoS Pathog
2021
34402452
Mucosal AIDS virus transmission is enhanced by antiviral IgG isolated early in infection.
AIDS
2021
34413855
Cooperation Between Systemic IgG1 and Mucosal Dimeric IgA2 Monoclonal Anti-HIV Env Antibodies: Passive Immunization Protects Indian Rhesus Macaques Against Mucosal SHIV Challenges.
Front Immunol
2021
34061907
PET/CT targeted tissue sampling reveals virus specific dIgA can alter the distribution and localization of HIV after rectal exposure.
PLoS Pathog
2021
34091299
Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates.
Biomaterials
2021
32343743
Correction:Â ALVAC-HIV B/C candidate HIV vaccine efficacy dependent on neutralization profile of challenge virus and adjuvant dose and type.
PLoS Pathog
2020
32849652
Immunoglobulin M: An Ancient Antiviral Weapon - Rediscovered.
Front Immunol
2020
32130229
Immunotherapy with DNA vaccine and live attenuated rubella/SIV gag vectors plus early ART can prevent SIVmac251 viral rebound in acutely infected rhesus macaques.
PLoS One
2020
30760566
Adaptation of an R5 Simian-Human Immunodeficiency Virus Encoding an HIV Clade A Envelope with or without Ablation of Adaptive Host Immunity: Differential Selection of Viral Mutants.
J Virol
2019
31771162
Mucosal Antibodies: Defending Epithelial Barriers against HIV-1 Invasion.
Vaccines (Basel)
2019
31035848
Lymphocytes upregulate CD36 in adipose tissue and liver.
Adipocyte
2019
29093095
Combination Adenovirus and Protein Vaccines Prevent Infection or Reduce Viral Burden after Heterologous Clade C Simian-Human Immunodeficiency Virus Mucosal Challenge.
J Virol
2018
29743361
Novel Strategy To Adapt Simian-Human Immunodeficiency Virus E1 Carrying <i>env</i> from an RV144 Volunteer to Rhesus Macaques: Coreceptor Switch and Final Recovery of a Pathogenic Virus with Exclusive R5 Tropism.
J Virol
2018
29762161
Anti-HIV IgM protects against mucosal SHIV transmission.
AIDS
2018
29563297
Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques.
J Virol
2018
29097089
Anti-HIV Passive Immunization: New Weapons in the Arsenal.
Trends Microbiol
2017
28463876
Systemic and topical use of monoclonal antibodies to prevent the sexual transmission of HIV.
AIDS
2017
28422786
Antibody-mediated immune exclusion of HIV.
Curr Opin HIV AIDS
2017
29176985
Mucosal IgA Responses: Damaged in Established HIV Infection-Yet, Effective Weapon against HIV Transmission.
Front Immunol
2017
25174584
Massive occlusive thrombosis of the pulmonary artery in pigtailed macaques chronically infected with R5-tropic simian-human immunodeficiency virus.
J Med Primatol
2015
25769884
Defense-in-depth by mucosally administered anti-HIV dimeric IgA2 and systemic IgG1 mAbs: complete protection of rhesus monkeys from mucosal SHIV challenge.
Vaccine
2015
24444350
Passive immunization of macaques with polyclonal anti-SHIV IgG against a heterologous tier 2 SHIV: outcome depends on IgG dose.
Retrovirology
2014
25499540
Are anti-HIV IgAs good guys or bad guys?
Retrovirology
2014
25245933
Multimodality vaccination against clade C SHIV: partial protection against mucosal challenges with a heterologous tier 2 virus.
Vaccine
2014
23528732
Impact of antibody quality and anamnestic response on viremia control post-challenge in a combined Tat/Env vaccine regimen in rhesus macaques.
Virology
2013
24278022
The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells.
PLoS Pathog
2013
24098702
Live attenuated Rev-independent Nef¯SIV enhances acquisition of heterologous SIVsmE660 in acutely vaccinated rhesus macaques.
PLoS One
2013
23840566
Variations in the Biological Functions of HIV-1 Clade C Envelope in a SHIV-Infected Rhesus Macaque during Disease Progression.
PLoS One
2013
23775002
Anti-HIV IgA isotypes: differential virion capture and inhibition of transcytosis are linked to prevention of mucosal R5 SHIV transmission.
AIDS
2013
23800339
Live-virus exposure of vaccine-protected macaques alters the anti-HIV-1 antibody repertoire in the absence of viremia.
Retrovirology
2013
23758766
Clade C HIV-1 isolates circulating in Southern Africa exhibit a greater frequency of dicysteine motif-containing Tat variants than those in Southeast Asia and cause increased neurovirulence.
Retrovirology
2013
23388727
Novel biopanning strategy to identify epitopes associated with vaccine protection.
J Virol
2013
21941166
High-level, lasting antiviral immunity induced by a bimodal AIDS vaccine and boosted by live-virus exposure: prevention of viremia.
AIDS
2012
22970187
Identification and characterization of a broadly cross-reactive HIV-1 human monoclonal antibody that binds to both gp120 and gp41.
PLoS One
2012
22737224
Isolation of monoclonal antibodies with predetermined conformational epitope specificity.
PLoS One
2012
22828501
Phage display-directed discovery of LEDGF/p75 binding cyclic peptide inhibitors of HIV replication.
Mol Ther
2012
22427893
Dynamics of envelope evolution in clade C SHIV-infected pig-tailed macaques during disease progression analyzed by ultra-deep pyrosequencing.
PLoS One
2012
21244649
Prior exposure to an attenuated Listeria vaccine does not reduce immunogenicity: pre-clinical assessment of the efficacy of a Listeria vaccine in the induction of immune responses against HIV.
J Immune Based Ther Vaccines
2011
22081778
No acquisition: a new ambition for HIV vaccine development?
Curr Opin Virol
2011
21829749
Schistosoma mansoni enhances host susceptibility to mucosal but not intravenous challenge by R5 Clade C SHIV.
PLoS Negl Trop Dis
2011
21799765
Vaccination against heterologous R5 clade C SHIV: prevention of infection and correlates of protection.
PLoS One
2011
21895680
Molecularly cloned SHIV-CN97001: a replication-competent, R5 simian/human immunodeficiency virus containing env of a primary Chinese HIV-1 clade C isolate.
J Med Primatol
2011
21957314
Efficiency of neutralizing antibodies targeting the CD4-binding site: influence of conformational masking by the V2 loop in R5-tropic clade C simian-human immunodeficiency virus.
J Virol
2011
1 - 50 of 202
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