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Author Details

Johann S de Bono
The Institute for Cancer Research
1999
654
128
PMIDPaper TitleJournal TitlePublished Year
37783649PARP inhibitors for prostate cancer.Semin Oncol2024
36114082B7-H3 as a Therapeutic Target in Advanced Prostate Cancer.Eur Urol2023
37491606A HUWE1 defect causes PARP inhibitor resistance by modulating the BRCA1-â¿¿11q splice variant.Oncogene2023
37751307The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer.J Clin Invest2023
37847874Poly(ADP-ribose) Polymerase Inhibitor Combinations in First-Line Metastatic Castration-Resistant Prostate Cancer: Increasing Toxicity With Unclear Benefits.J Clin Oncol2023
37844613Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance.Nature2023
37652207Development and Validation of a New BAG-1L-Specific Antibody to Quantify BAG-1L Protein Expression in Advanced Prostate Cancer.Lab Invest2023
37502956NSD2 maintains lineage plasticity and castration-resistance in neuroendocrine prostate cancer.bioRxiv2023
37537253A Phase Ib/II study of IGF-neutralising antibody xentuzumab with enzalutamide in metastatic castration-resistant prostate cancer.Br J Cancer2023
35750582Patient-reported Outcomes in Men with Metastatic Castration-resistant Prostate Cancer Harboring DNA Damage Response Alterations Treated with Talazoparib: Results from TALAPRO-1.Eur Urol2023
37460872The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells.Nat Cancer2023
37087376PARP Inhibitors for Prostate Cancer: Tangled up in PROfound and PROpel (and TALAPRO-2) Blues.Eur Urol2023
37040594External Validation of a Prognostic Model of Overall Survival in Men With Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer.J Clin Oncol2023
37269841Health-related quality of life and pain outcomes with [<sup>177</sup>Lu]Lu-PSMA-617 plus standard of care versus standard of care in patients with metastatic castration-resistant prostate cancer (VISION): a multicentre, open-label, randomised, phase 3 trial.Lancet Oncol2023
37003085Management of patients with advanced prostate cancer-metastatic and/or castration-resistant prostate cancer: Report of the Advanced Prostate Cancer Consensus Conference (APCCC) 2022.Eur J Cancer2023
37032186Reply to Timothée Olivier, Kerrington Powell, Vinay Prasad. Lutetium-177-PSMA-617 in Metastatic Castration-resistant Prostate Cancer: Limitations of the VISION Trial. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2022.08.022.Eur Urol2023
36964041Erratum to "B7-H3 as a Therapeutic Target in Advanced Prostate Cancer" [Eur Urol 2023;83(3):224-38].Eur Urol2023
37355762Critical role of antioxidant programs in enzalutamide-resistant prostate cancer.Oncogene2023
36697317Safety Profile of Ipatasertib Plus Abiraterone vs Placebo Plus Abiraterone in Metastatic Castration-resistant Prostate Cancer.Clin Genitourin Cancer2023
36806722Systematic study of tissue factor expression in solid tumors.Cancer Rep (Hoboken)2023
36609007A Transgender Patient with Prostate Cancer: Lessons Learnt.Eur Urol2023
36528479Corrigendum to "Pembrolizumab plus Olaparib in Patients with Metastatic Castration-resistant Prostate Cancer: Long-term Results from the Phase 1b/2 KEYNOTE-365 Cohort A Study" [Eur Urol 83 (2023) 15-26].Eur Urol2023
36494221Management of Patients with Advanced Prostate Cancer. Part I: Intermediate-/High-risk and Locally Advanced Disease, Biochemical Relapse, and Side Effects of Hormonal Treatment: Report of the Advanced Prostate Cancer Consensus Conference 2022.Eur Urol2023
36725887Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth.Oncogene2023
36043882Detection of BRCA1, BRCA2, and ATM Alterations in Matched Tumor Tissue and Circulating Tumor DNA in Patients with Prostate Cancer Screened in PROfound.Clin Cancer Res2023
36055895Pembrolizumab plus Olaparib in Patients with Metastatic Castration-resistant Prostate Cancer: Long-term Results from the Phase 1b/2 KEYNOTE-365 Cohort A Study.Eur Urol2023
36318705Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2, or ATM Alterations Identified by Testing Circulating Tumor DNA.Clin Cancer Res2023
34167925Prostate-specific Membrane Antigen Biology in Lethal Prostate Cancer and its Therapeutic Implications.Eur Urol Focus2022
35737639Clinical activity of CC-90011, an oral, potent, and reversible LSD1 inhibitor, in advanced malignancies.Cancer2022
35677318Neutropenia, neutrophilia, and neutrophil-lymphocyte ratio as prognostic markers in patients with metastatic castration-resistant prostate cancer.Ther Adv Med Oncol2022
35584120H3K9 methylation drives resistance to androgen receptor-antagonist therapy in prostate cancer.Proc Natl Acad Sci U S A2022
35349486Targeting radioresistance and replication fork stability in prostate cancer.JCI Insight2022
35440417Corrigendum to "What Experts Think About Prostate Cancer Management During the COVID-19 Pandemic: Report from the Advanced Prostate Cancer Consensus Conference 2021" [Eur Urol 82(1):6-11].Eur Urol2022
35643841Statin and metformin use and outcomes in patients with castration-resistant prostate cancer treated with enzalutamide: A meta-analysis of AFFIRM, PREVAIL and PROSPER.Eur J Cancer2022
35397952Pembrolizumab Plus Docetaxel and Prednisone in Patients with Metastatic Castration-resistant Prostate Cancer: Long-term Results from the Phase 1b/2 KEYNOTE-365 Cohort B Study.Eur Urol2022
35695870Assessment of Androgen Receptor Splice Variant-7 as a Biomarker of Clinical Response in Castration-Sensitive Prostate Cancer.Clin Cancer Res2022
35568679Effects of metformin and statins on outcomes in men with castration-resistant metastatic prostate cancer: Secondary analysis of COU-AA-301 and COU-AA-302.Eur J Cancer2022
35491356Immune Biomarkers in Metastatic Castration-resistant Prostate Cancer.Eur Urol Oncol2022
35717027Phase 1, dose-escalation study of guadecitabine (SGI-110) in combination with pembrolizumab in patients with solid tumors.J Immunother Cancer2022
35450732Management of Patients with Advanced Prostate Cancer: Report from the Advanced Prostate Cancer Consensus Conference 2021.Eur Urol2022
35656509Oligoprogression in Metastatic, Castrate-Resistant Prostate Cancer-Prevalence and Current Clinical Practice.Front Oncol2022
35552383Prostate-Specific Membrane Antigen Expression and Response to DNA Damaging Agents in Prostate Cancer.Clin Cancer Res2022
36273494SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance.Cancer Res2022
35984704A Phase I Trial of CT900, a Novel α-Folate Receptor-Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer.Clin Cancer Res2022
36124924Talazoparib, a Poly(ADP-ribose) Polymerase Inhibitor, for Metastatic Castration-resistant Prostate Cancer and DNA Damage Response Alterations: TALAPRO-1 Safety Analyses.Oncologist2022
35157830Pain and health-related quality of life with olaparib versus physician's choice of next-generation hormonal drug in patients with metastatic castration-resistant prostate cancer with homologous recombination repair gene alterations (PROfound): an open-label, randomised, phase 3 trial.Lancet Oncol2022
35317841A non-coding RNA balancing act: miR-346-induced DNA damage is limited by the long non-coding RNA NORAD in prostate cancer.Mol Cancer2022
35247924A Phase I Study Investigating AZD8186, a Potent and Selective Inhibitor of PI3Kβ/δ, in Patients with Advanced Solid Tumors.Clin Cancer Res2022
35092476Multiparametric bone MRI can improve CT-guided bone biopsy target selection in cancer patients and increase diagnostic yield and feasibility of next-generation tumour sequencing.Eur Radiol2022
35091440Tumor Genomic Testing for &gt;4,000 Men with Metastatic Castration-resistant Prostate Cancer in the Phase III Trial PROfound (Olaparib).Clin Cancer Res2022
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Collaborators

The Institute of Cancer Research
Co-authored papers 116
Vall d'Hebron Institute of Oncology, Vall d'Hebron University Hospital Campus
Co-authored papers 67
The Institute of Cancer Research
Co-authored papers 66
Memorial Sloan Kettering Cancer Center
Co-authored papers 66
The Institute of Cancer Research
Co-authored papers 59
The Institute for Cancer Research
Co-authored papers 53
The Institute of Cancer Research
Co-authored papers 52
The Institute for Cancer Research
Co-authored papers 52
Meyer Cancer Center, Englander Institute for Precision Medicine
Co-authored papers 44
University of Montreal Health Center
Co-authored papers 41
Tulane University School of Medicine
Co-authored papers 40
The Institute of Cancer Research
Co-authored papers 37
University of British Columbia
Co-authored papers 35
Astex Pharmaceuticals
Co-authored papers 35
Theageneion Anticancer Hospital
Co-authored papers 31
University of Washington and Fred Hutchinson Cancer Research Center
Co-authored papers 30
University of California san francisco
Co-authored papers 28
The Institute of Cancer Research
Co-authored papers 27
Memorial Sloan Kettering Cancer Center
Co-authored papers 27
Vall d'Hebron Institute of Oncology, Vall d'Hebron Barcelona Hospital Campus
Co-authored papers 25
Memorial Sloan Kettering Cancer Center
Co-authored papers 23
Lank Center for Genitourinary Oncology, Dana-Farber Cancer Institute
Co-authored papers 23
The Institute for Cancer Research
Co-authored papers 23
Northwestern University
Co-authored papers 23
University of Bern
Co-authored papers 23
OHSU Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 23
Radboud university medical center
Co-authored papers 22
The Institute of Cancer Research
Co-authored papers 20
Fred Hutchinson Cancer Center
Co-authored papers 20
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