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| 36596875 | Type I interferon signaling facilitates resolution of acute liver injury by priming macrophage polarization. | Cell Mol Immunol | 2023 |
| 36717564 | Mechanism of regulation of the Helicobacter pylori Cagβ ATPase by CagZ. | Nat Commun | 2023 |
| 36758305 | Design and syntheses of a bimolecular STING agonist based on the covalent STING antagonist. | Eur J Med Chem | 2023 |
| 35963848 | Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH). | Signal Transduct Target Ther | 2022 |
| 35799071 | Transmissible ER stress between macrophages and tumor cells configures tumor microenvironment. | Cell Mol Life Sci | 2022 |
| 32759968 | A virus-induced conformational switch of STAT1-STAT2 dimers boosts antiviral defenses. | Cell Res | 2021 |
| 33827893 | Regulation of Anion Channel LRRC8 Volume-Regulated Anion Channels in Transport of 2'3'-Cyclic GMP-AMP and Cisplatin under Steady State and Inflammation. | J Immunol | 2021 |
| 33597177 | TSC1 Suppresses Macrophage Necroptosis for the Control of Infection by Fungal Pathogen <i>Candida albicans</i>. | Immunohorizons | 2021 |
| 33779055 | Natural Triterpenoids Isolated from Akebia trifoliata Stem Explants Exert a Hypoglycemic Effect via α-Glucosidase Inhibition and Glucose Uptake Stimulation in Insulin-Resistant HepG2 Cells. | Chem Biodivers | 2021 |
| 34830015 | Xanthohumol Is a Potent Pan-Inhibitor of Coronaviruses Targeting Main Protease. | Int J Mol Sci | 2021 |
| 30852741 | Overexpression of Pyruvate Kinase M2 in Tumor Tissues Is Associated with Poor Prognosis in Patients with Hepatocellular Carcinoma. | Pathol Oncol Res | 2020 |
| 31802375 | Combination of a novel microtubule inhibitor MBRI-001 and gemcitabine synergistically induces cell apoptosis by increasing DNA damage in pancreatic cancer cell lines. | Invest New Drugs | 2020 |
| 32829850 | Sulfated polymannuroguluronate TGC161 ameliorates leukopenia by inhibiting CD4<sup>+</sup> T cell apoptosis. | Carbohydr Polym | 2020 |
| 32682051 | Inhibition of IRAK4 kinase activity improves ethanol-induced liver injury in mice. | J Hepatol | 2020 |
| 32532922 | Loss of ZIP facilitates JAK2-STAT3 activation in tamoxifen-resistant breast cancer. | Proc Natl Acad Sci U S A | 2020 |
| 31612426 | Discovery and evaluation of Atopaxar hydrobromide, a novel JAK1 and JAK2 inhibitor, selectively induces apoptosis of cancer cells with constitutively activated STAT3. | Invest New Drugs | 2020 |
| 31087223 | Zelnorm, an agonist of 5-Hydroxytryptamine 4-receptor, acts as a potential antitumor drug by targeting JAK/STAT3 signaling. | Invest New Drugs | 2020 |
| 30726872 | E2F is required for STAT3-mediated upregulation of cyclin B1 and Cdc2 expressions and contributes to G2-M phase transition. | Acta Biochim Biophys Sin (Shanghai) | 2019 |
| 31725079 | Chrysin Alleviates Chronic Hypoxia-Induced Pulmonary Hypertension by Reducing Intracellular Calcium Concentration in Pulmonary Arterial Smooth Muscle Cells. | J Cardiovasc Pharmacol | 2019 |
| 31359244 | TGF-β2 antagonizes IL-6-promoted cell survival. | Mol Cell Biochem | 2019 |
| 31433805 | TSC1/mTOR-controlled metabolic-epigenetic cross talk underpins DC control of CD8+ T-cell homeostasis. | PLoS Biol | 2019 |
| 31320068 | A β-1,3/1,6-glucan from Durvillaea Antarctica inhibits tumor progression in vivo as an immune stimulator. | Carbohydr Polym | 2019 |
| 31035725 | The Inhibitory Effect of Propylene Glycol Alginate Sodium Sulfate on Fibroblast Growth Factor 2-Mediated Angiogenesis and Invasion in Murine Melanoma B16-F10 Cells In Vitro. | Mar Drugs | 2019 |
| 30732758 | Structure-activity relationship of propylene glycol alginate sodium sulfate derivatives for blockade of selectins binding to tumor cells. | Carbohydr Polym | 2019 |
| 29138867 | Effect of xanthohumol on Th1/Th2 balance in a breast cancer mouse model. | Oncol Rep | 2018 |
| 29422966 | Inhibition of breast cancer cell survival by Xanthohumol via modulation of the Notch signaling pathway <i>in vivo</i> and <i>in vitro</i>. | Oncol Lett | 2018 |
| 29581268 | IRF9 and unphosphorylated STAT2 cooperate with NF-κB to drive IL6 expression. | Proc Natl Acad Sci U S A | 2018 |
| 27852626 | Negative regulation of type I IFN signaling by phosphorylation of STAT2 on T387. | EMBO J | 2017 |
| 28260066 | Repression of the expression of TET2 by ZEB1 contributes to invasion and growth in glioma cells. | Mol Med Rep | 2017 |
| 27793668 | ZIP restores estrogen receptor expression and response to Tamoxifen in estrogen receptor negative tumors. | Biochem Biophys Res Commun | 2016 |
| 25583084 | Dehydrocrenatidine is a novel janus kinase inhibitor. | Mol Pharmacol | 2015 |
| 24401319 | TPCA-1 is a direct dual inhibitor of STAT3 and NF-κB and regresses mutant EGFR-associated human non-small cell lung cancers. | Mol Cancer Ther | 2014 |
| 25217633 | Critical role for lysine 685 in gene expression mediated by transcription factor unphosphorylated STAT3. | J Biol Chem | 2014 |
| 25107644 | N6-substituted adenosine analogues, a novel class of JAK2 inhibitors, potently block STAT3 signaling in human cancer cells. | Cancer Lett | 2014 |
| 24735734 | Activation of Akt protects cancer cells from growth inhibition induced by PKM2 knockdown. | Cell Biosci | 2014 |
| 23704931 | Brevilin A, a novel natural product, inhibits janus kinase activity and blocks STAT3 signaling in cancer cells. | PLoS One | 2013 |
| 24082147 | STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor. | Proc Natl Acad Sci U S A | 2013 |
| 23593410 | PMS1077 sensitizes TNF-α induced apoptosis in human prostate cancer cells by blocking NF-κB signaling pathway. | PLoS One | 2013 |
| 22581330 | STAT3 mutations correlated with hyper-IgE syndrome lead to blockage of IL-6/STAT3 signalling pathway. | J Biosci | 2012 |
| 22753228 | Signal transducer and activator of transcription 3 promotes angiogenesis and drives malignant progression in glioma. | Neuro Oncol | 2012 |
| 22621920 | ATP depletion triggers acute myeloid leukemia differentiation through an ATR/Chk1 protein-dependent and p53 protein-independent pathway. | J Biol Chem | 2012 |
| 21166594 | The functions of signal transducers and activators of transcriptions 1 and 3 as cytokine-inducible proteins. | J Interferon Cytokine Res | 2011 |
| 21625555 | Modeling a new water channel that allows SET9 to dimethylate p53. | PLoS One | 2011 |
| 21481791 | Nonreceptor tyrosine kinase BMX maintains self-renewal and tumorigenic potential of glioblastoma stem cells by activating STAT3. | Cancer Cell | 2011 |
| 20812915 | PMS-1077, a PAF antagonist, induced differentiation of HL-60 cells with its novel activity. | Cell Biol Int | 2010 |
| 21317457 | Sumoylation of vimentin354 is associated with PIAS3 inhibition of glioma cell migration. | Oncotarget | 2010 |
| 21098664 | Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes. | Proc Natl Acad Sci U S A | 2010 |
| 17993285 | Seleno-podophyllotoxin derivatives induce hepatoma SMMC-7721 cell apoptosis through Bax pathway. | Cell Biol Int | 2008 |
| 19179760 | Redifferentiation of human hepatoma cells (SMMC-7721) induced by two new highly oxygenated bisabolane-type sesquiterpenes. | J Biosci | 2008 |
| 18675342 | WITHDRAWN: SOCS3 mediates IL-1beta-dependent inhibition of IL-6-induced gene expression. | Cell Signal | 2008 |