Author details

Full Name

Brooke Fiala

Affiliation

ORCID

Career Start Year

2018

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36888664	Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains.	Proc Natl Acad Sci U S A	2023
37689061	Multivalent antigen display on nanoparticle immunogens increases B cell clonotype diversity and neutralization breadth to pneumoviruses.		2023
36713406	Design and immunological evaluation of two-component protein nanoparticle vaccines for East Coast fever.	Front Immunol	2023
35976993	Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine.	Sci Transl Med	2022
35705092	Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge.	Cell Reports Medicine	2022
35584193	Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region.	PLoS Pathog	2022
36206752	Antigen- and scaffold-specific antibody responses to protein nanoparticle immunogens.	Cell Reports Medicine	2022
35988541	Distinct sensitivities to SARS-CoV-2 variants in vaccinated humans and mice.	Cell Rep	2022
35606518	Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice.	NPJ Vaccines	2022
34493582	Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice.	Proc Natl Acad Sci U S A	2021
33535236	Dynamics of Neutralizing Antibody Titers in the Months After Severe Acute Respiratory Syndrome Coronavirus 2 Infection.	J Infect Dis	2021
34267764	Stabilization of the SARS-CoV-2 Spike Receptor-Binding Domain Using Deep Mutational Scanning and Structure-Based Design.	Front Immunol	2021
33873199	Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.	Nature	2021
33758839	Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.	bioRxiv	2021
33594366	Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates.	bioRxiv	2021
33296701	Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19.	Cell	2021
34619077	Elicitation of broadly protective sarbecovirus immunity by receptor-binding domain nanoparticle vaccines.	Cell	2021
33160446	Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2.	Cell	2020
32818218	Functional SARS-CoV-2-specific immune memory persists after mild COVID-19.	Res Sq	2020
32817957	Functional SARS-CoV-2-specific immune memory persists after mild COVID-19.	medRxiv	2020
31537780	Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.	Nat Commun	2019
30849373	Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus.	Cell	2019
29976752	Discovery and engineering of enhanced SUMO protease enzymes.	J Biol Chem	2018