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Author Details
Full Name
Partho Ghosh
Affiliation
University of California
ORCID
Career Start Year
1986
Papers
77
H Index
37
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36643388
Structural and biochemical characterization of <i>Leptospira interrogans</i> Lsa45 reveals a penicillin-binding protein with esterase activity.
Process Biochem
2023
37390991
A conserved 3D pattern in a Streptococcus pyogenes M protein immunogen elicits M-type crossreactivity.
J Biol Chem
2023
37438348
Structural and photophysical characterization of the small ultra-red fluorescent protein.
Nat Commun
2023
36103556
Strengthening of enterococcal biofilms by Esp.
PLoS Pathog
2022
35726694
An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37.
Elife
2022
35724830
Contribution of Streptococcus pyogenes M87 protein to innate immune resistance and virulence.
Microb Pathog
2022
33367793
Determinants of adenine-mutagenesis in diversity-generating retroelements.
Nucleic Acids Res
2021
33630944
Nonimmune antibody interactions of Group A Streptococcus M and M-like proteins.
PLoS Pathog
2021
30629599
Crystal structure of a Thermus aquaticus diversity-generating retroelement variable protein.
PLoS One
2019
28867148
Variation, Indispensability, and Masking in the M protein.
Trends Microbiol
2018
30007279
Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex.
Nucleic Acids Res
2018
29186518
Diversity-generating retroelements: natural variation, classification and evolution inferred from a large-scale genomic survey.
Nucleic Acids Res
2018
28604710
Erratum: Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol
2017
28220899
Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones.
Sci Rep
2017
28368387
Retroelement-guided protein diversification abounds in vast lineages of Bacteria and Archaea.
Nat Microbiol
2017
28784982
Group A streptococcal M protein activates the NLRP3 inflammasome.
Nat Microbiol
2017
27512043
Coiled-coil destabilizing residues in the group A Streptococcus M1 protein are required for functional interaction.
Proc Natl Acad Sci U S A
2016
27595425
Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.
Nat Microbiol
2016
27578274
Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements.
BMC Struct Biol
2016
25798780
Targeted diversity generation by intraterrestrial archaea and archaeal viruses.
Nat Commun
2015
26468750
Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing.
Cell Host Microbe
2015
24356958
The fibrinogen-binding M1 protein reduces pharyngeal cell adherence and colonization phenotypes of M1T1 group A Streptococcus.
J Biol Chem
2014
26104433
Diversity-generating Retroelements in Phage and Bacterial Genomes.
Microbiol Spectr
2014
25479287
Structure of the essential Plasmodium host cell traversal protein SPECT1.
PLoS One
2014
25266727
Mutual exclusivity of hyaluronan and hyaluronidase in invasive group A Streptococcus.
J Biol Chem
2014
23273427
Structure of the essential diversity-generating retroelement protein bAvd and its functionally important interaction with reverse transcriptase.
Structure
2013
23935040
Functionally essential interaction between Yersinia YscO and the T3S4 domain of YscP.
J Bacteriol
2013
23633572
Surface display of a massively variable lipoprotein by a Legionella diversity-generating retroelement.
Proc Natl Acad Sci U S A
2013
23443671
Coiled-coil irregularities of the M1 protein structure promote M1-fibrinogen interaction and influence group A Streptococcus host cell interactions and virulence.
J Mol Med (Berl)
2013
22320351
Two translation products of Yersinia yscQ assemble to form a complex essential to type III secretion.
Biochemistry
2012
22942247
Structure and interactions of the cytoplasmic domain of the Yersinia type III secretion protein YscD.
J Bacteriol
2012
23150986
Structure and glycolipid binding properties of the nematicidal protein Cry5B.
Biochemistry
2012
21475196
Streptococcal M1 protein constructs a pathological host fibrinogen network.
Nature
2011
22027416
[Structural basis for streptococcal toxic shock syndrome].
Med Sci (Paris)
2011
21873231
Conservation of the C-type lectin fold for massive sequence variation in a Treponema diversity-generating retroelement.
Proc Natl Acad Sci U S A
2011
21557065
The nonideal coiled coil of M protein and its multifarious functions in pathogenesis.
Adv Exp Med Biol
2011
21294157
Specificity and cooperativity at β-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactions.
Proteins
2011
21408619
Global functional analyses of cellular responses to pore-forming toxins.
PLoS Pathog
2011
20382763
A solvent-exposed patch in chaperone-bound YopE is required for translocation by the type III secretion system.
J Bacteriol
2010
21084668
Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 1996. 384: 134-141.
J Immunol
2010
20485518
Listeria monocytogenes internalin B activates junctional endocytosis to accelerate intestinal invasion.
PLoS Pathog
2010
20020046
An MHC-I cytoplasmic domain/HIV-1 Nef fusion protein binds directly to the mu subunit of the AP-1 endosomal coat complex.
PLoS One
2009
20375578
M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition.
J Innate Immun
2009
18323455
Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence.
Science
2008
18502763
The type III secretion chaperone SycE promotes a localized disorder-to-order transition in the natively unfolded effector YopE.
J Biol Chem
2008
18532877
Selective ligand recognition by a diversity-generating retroelement variable protein.
PLoS Biol
2008
17305366
Investigation of the mechanism of binding between internalin B and heparin using surface plasmon resonance.
Biochemistry
2007
16531241
Conformational flexibility in the multidrug efflux system protein AcrA.
Structure
2006
16413487
Identification of a bacterial type III effector family with G protein mimicry functions.
Cell
2006
16410353
Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase.
Proc Natl Acad Sci U S A
2006
1 - 50 of 77
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row(s) 1 - 30 of 30
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University of Toronto
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Linda S Brinen
The Joint Center for Structural Genomics, Stanford University
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Sharon L Reed
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