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Author Details

Partho Ghosh
University of California
1986
77
37
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36643388Structural and biochemical characterization of <i>Leptospira interrogans</i> Lsa45 reveals a penicillin-binding protein with esterase activity.Process Biochem2023
37390991A conserved 3D pattern in a Streptococcus pyogenes M protein immunogen elicits M-type crossreactivity.J Biol Chem2023
37438348Structural and photophysical characterization of the small ultra-red fluorescent protein.Nat Commun2023
36103556Strengthening of enterococcal biofilms by Esp.PLoS Pathog2022
35726694An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37.Elife2022
35724830Contribution of Streptococcus pyogenes M87 protein to innate immune resistance and virulence.Microb Pathog2022
33367793Determinants of adenine-mutagenesis in diversity-generating retroelements.Nucleic Acids Res2021
33630944Nonimmune antibody interactions of Group A Streptococcus M and M-like proteins.PLoS Pathog2021
30629599Crystal structure of a Thermus aquaticus diversity-generating retroelement variable protein.PLoS One2019
28867148Variation, Indispensability, and Masking in the M protein.Trends Microbiol2018
30007279Template-assisted synthesis of adenine-mutagenized cDNA by a retroelement protein complex.Nucleic Acids Res2018
29186518Diversity-generating retroelements: natural variation, classification and evolution inferred from a large-scale genomic survey.Nucleic Acids Res2018
28604710Erratum: Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.Nat Microbiol2017
28220899Group A Streptococcal M1 Protein Provides Resistance against the Antimicrobial Activity of Histones.Sci Rep2017
28368387Retroelement-guided protein diversification abounds in vast lineages of Bacteria and Archaea.Nat Microbiol2017
28784982Group A streptococcal M protein activates the NLRP3 inflammasome.Nat Microbiol2017
27512043Coiled-coil destabilizing residues in the group A Streptococcus M1 protein are required for functional interaction.Proc Natl Acad Sci U S A2016
27595425Conserved patterns hidden within group A Streptococcus M protein hypervariability recognize human C4b-binding protein.Nat Microbiol2016
27578274Conservation of the C-type lectin fold for accommodating massive sequence variation in archaeal diversity-generating retroelements.BMC Struct Biol2016
25798780Targeted diversity generation by intraterrestrial archaea and archaeal viruses.Nat Commun2015
26468750Group A Streptococcal M1 Protein Sequesters Cathelicidin to Evade Innate Immune Killing.Cell Host Microbe2015
24356958The fibrinogen-binding M1 protein reduces pharyngeal cell adherence and colonization phenotypes of M1T1 group A Streptococcus.J Biol Chem2014
26104433Diversity-generating Retroelements in Phage and Bacterial Genomes.Microbiol Spectr2014
25479287Structure of the essential Plasmodium host cell traversal protein SPECT1.PLoS One2014
25266727Mutual exclusivity of hyaluronan and hyaluronidase in invasive group A Streptococcus.J Biol Chem2014
23273427Structure of the essential diversity-generating retroelement protein bAvd and its functionally important interaction with reverse transcriptase.Structure2013
23935040Functionally essential interaction between Yersinia YscO and the T3S4 domain of YscP.J Bacteriol2013
23633572Surface display of a massively variable lipoprotein by a Legionella diversity-generating retroelement.Proc Natl Acad Sci U S A2013
23443671Coiled-coil irregularities of the M1 protein structure promote M1-fibrinogen interaction and influence group A Streptococcus host cell interactions and virulence.J Mol Med (Berl)2013
22320351Two translation products of Yersinia yscQ assemble to form a complex essential to type III secretion.Biochemistry2012
22942247Structure and interactions of the cytoplasmic domain of the Yersinia type III secretion protein YscD.J Bacteriol2012
23150986Structure and glycolipid binding properties of the nematicidal protein Cry5B.Biochemistry2012
21475196Streptococcal M1 protein constructs a pathological host fibrinogen network.Nature2011
22027416[Structural basis for streptococcal toxic shock syndrome].Med Sci (Paris)2011
21873231Conservation of the C-type lectin fold for massive sequence variation in a Treponema diversity-generating retroelement.Proc Natl Acad Sci U S A2011
21557065The nonideal coiled coil of M protein and its multifarious functions in pathogenesis.Adv Exp Med Biol2011
21294157Specificity and cooperativity at β-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactions.Proteins2011
21408619Global functional analyses of cellular responses to pore-forming toxins.PLoS Pathog2011
20382763A solvent-exposed patch in chaperone-bound YopE is required for translocation by the type III secretion system.J Bacteriol2010
21084668Structure of the complex between human T-cell receptor, viral peptide and HLA-A2. Nature. 1996. 384: 134-141.J Immunol2010
20485518Listeria monocytogenes internalin B activates junctional endocytosis to accelerate intestinal invasion.PLoS Pathog2010
20020046An MHC-I cytoplasmic domain/HIV-1 Nef fusion protein binds directly to the mu subunit of the AP-1 endosomal coat complex.PLoS One2009
20375578M1 protein allows Group A streptococcal survival in phagocyte extracellular traps through cathelicidin inhibition.J Innate Immun2009
18323455Coiled-coil irregularities and instabilities in group A Streptococcus M1 are required for virulence.Science2008
18502763The type III secretion chaperone SycE promotes a localized disorder-to-order transition in the natively unfolded effector YopE.J Biol Chem2008
18532877Selective ligand recognition by a diversity-generating retroelement variable protein.PLoS Biol2008
17305366Investigation of the mechanism of binding between internalin B and heparin using surface plasmon resonance.Biochemistry2007
16531241Conformational flexibility in the multidrug efflux system protein AcrA.Structure2006
16413487Identification of a bacterial type III effector family with G protein mimicry functions.Cell2006
16410353Molecular basis for substrate recognition by MTMR2, a myotubularin family phosphoinositide phosphatase.Proc Natl Acad Sci U S A2006
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Collaborators

university of california san diego School of Medicine
Co-authored papers 16
and the California NanoSystems Institute, University of California los angeles
Co-authored papers 10
University of California San Francisco
Co-authored papers 4
a division of The Scripps Research Institute La Jolla
Co-authored papers 3
Eastern University
Co-authored papers 3
Department of Pediatrics University of California San Diego
Co-authored papers 2
University of California
Co-authored papers 2
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University of California San Diego
Co-authored papers 2
University of St Andrews
Co-authored papers 2
University of California
Co-authored papers 2
Cubist Pharmaceuticals, Inc.
Co-authored papers 1
University of Virginia
Co-authored papers 1
University of Toronto
Co-authored papers 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of Toronto
Co-authored papers 1
The Joint Center for Structural Genomics, Stanford University
Co-authored papers 1
The Skaggs Institute for Chemical Biology, The Scripps Research Institute
Co-authored papers 1
university of california san diego Health
Co-authored papers 1
University of California at San Francisco
Co-authored papers 1
University of Washington
Co-authored papers 1
Co-authored papers 1
Bowling Green State University
Co-authored papers 1
University of California San Diego, USA VA San Diego Healthcare System
Co-authored papers 1
Lawrence Berkeley National Laboratory, University of California Santa Cruz
Co-authored papers 1
University of Calgary
Co-authored papers 1
Universitat Pompeu Fabra (UPF)
Co-authored papers 1
Rensselaer Polytechnic Institute
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University of California San Diego
Co-authored papers 1