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Author Details

Wai-Kwan Alfred Yung
University of Texas M.D. Anderson Cancer Center
1974
377
86
PMIDPaper TitleJournal TitlePublished Year
37935104Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma.J Clin Oncol2023
37935104Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma.J Clin Oncol2023
36471067The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location.Nat Genet2022
35380705Hypothetical generalized framework for a new imaging endpoint of therapeutic activity in early phase clinical trials in brain tumors.Neuro Oncol2022
35474131EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma.Neuro Oncol2022
36471067The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location.Nat Genet2022
35380705Hypothetical generalized framework for a new imaging endpoint of therapeutic activity in early phase clinical trials in brain tumors.Neuro Oncol2022
35474131EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma.Neuro Oncol2022
33420056Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation.Nat Commun2021
33738447The promise of DNA damage response inhibitors for the treatment of glioblastoma.Neurooncol Adv2021
33822177Report of National Brain Tumor Society roundtable workshop on innovating brain tumor clinical trials: building on lessons learned from COVID-19 experience.Neuro Oncol2021
33130879Radiographic read paradigms and the roles of the central imaging laboratory in neuro-oncology clinical trials.Neuro Oncol2021
33420056Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation.Nat Commun2021
33433610PARP-mediated PARylation of MGMT is critical to promote repair of temozolomide-induced O6-methylguanine DNA damage in glioblastoma.Neuro Oncol2021
34693288Results of a phase I trial to assess the safety of macitentan in combination with temozolomide for the treatment of recurrent glioblastoma.Neurooncol Adv2021
33738447The promise of DNA damage response inhibitors for the treatment of glioblastoma.Neurooncol Adv2021
33822177Report of National Brain Tumor Society roundtable workshop on innovating brain tumor clinical trials: building on lessons learned from COVID-19 experience.Neuro Oncol2021
34693288Results of a phase I trial to assess the safety of macitentan in combination with temozolomide for the treatment of recurrent glioblastoma.Neurooncol Adv2021
33433610PARP-mediated PARylation of MGMT is critical to promote repair of temozolomide-induced O6-methylguanine DNA damage in glioblastoma.Neuro Oncol2021
33130879Radiographic read paradigms and the roles of the central imaging laboratory in neuro-oncology clinical trials.Neuro Oncol2021
32166308A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma.Neuro Oncol2020
35665372The Promise of Poly(ADP-Ribose) Polymerase (PARP) Inhibitors in Gliomas.J Immunother Precis Oncol2020
31852834<i>EGFR</i> Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma.Clin Cancer Res2020
31776899A Phase Ib/II, open-label, multicenter study of INC280 (capmatinib) alone and in combination with buparlisib (BKM120) in adult patients with recurrent glioblastoma.J Neurooncol2020
32166308A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma.Neuro Oncol2020
31755915Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages.Neuro Oncol2020
33303700Safety and efficacy of magnetic seed localisation of non-palpable breast lesions: pilot study in a Chinese population.Hong Kong Med J2020
33235994Phase I/II study of sorafenib in combination with erlotinib for recurrent glioblastoma as part of a 3-arm sequential accrual clinical trial: NABTC 05-02.Neurooncol Adv2020
33427658Prognostic Significance of IDH1/2 Mutation and MGMT Promoter Methylation Status in RTOG 9813.Int J Radiat Oncol Biol Phys2020
33396284Molecular Mechanisms of Treatment Resistance in Glioblastoma.Int J Mol Sci2020
35665372The Promise of Poly(ADP-Ribose) Polymerase (PARP) Inhibitors in Gliomas.J Immunother Precis Oncol2020
31755915Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages.Neuro Oncol2020
31776899A Phase Ib/II, open-label, multicenter study of INC280 (capmatinib) alone and in combination with buparlisib (BKM120) in adult patients with recurrent glioblastoma.J Neurooncol2020
31852834<i>EGFR</i> Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma.Clin Cancer Res2020
33427658Prognostic Significance of IDH1/2 Mutation and MGMT Promoter Methylation Status in RTOG 9813.Int J Radiat Oncol Biol Phys2020
33303700Safety and efficacy of magnetic seed localisation of non-palpable breast lesions: pilot study in a Chinese population.Hong Kong Med J2020
33396284Molecular Mechanisms of Treatment Resistance in Glioblastoma.Int J Mol Sci2020
33235994Phase I/II study of sorafenib in combination with erlotinib for recurrent glioblastoma as part of a 3-arm sequential accrual clinical trial: NABTC 05-02.Neurooncol Adv2020
30951926Clinical trial participation of patients with glioblastoma at The University of Texas MD Anderson Cancer Center.Eur J Cancer2019
31748746Longitudinal molecular trajectories of diffuse glioma in adults.Nature2019
31815044BRCA1 identified as a modulator of temozolomide resistance in P53 wild-type GBM using a high-throughput shRNA-based synthetic lethality screening.Am J Cancer Res2019
30926639Prospective Clinical Sequencing of Adult Glioma.Mol Cancer Ther2019
31416846Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma.Cancer Res2019
30951926Clinical trial participation of patients with glioblastoma at The University of Texas MD Anderson Cancer Center.Eur J Cancer2019
31497354Wild-type <i>TP53</i> defined gamma-secretase inhibitor sensitivity and synergistic activity with doxorubicin in GSCs.Am J Cancer Res2019
31815044BRCA1 identified as a modulator of temozolomide resistance in P53 wild-type GBM using a high-throughput shRNA-based synthetic lethality screening.Am J Cancer Res2019
31748746Longitudinal molecular trajectories of diffuse glioma in adults.Nature2019
31416846Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma.Cancer Res2019
31497354Wild-type <i>TP53</i> defined gamma-secretase inhibitor sensitivity and synergistic activity with doxorubicin in GSCs.Am J Cancer Res2019
30926639Prospective Clinical Sequencing of Adult Glioma.Mol Cancer Ther2019
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Collaborators

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Co-authored papers 46
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David Geffen School of Medicine, University of California Los Angeles
Co-authored papers 44
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Co-authored papers 43
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Co-authored papers 42
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Co-authored papers 41
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Co-authored papers 41
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Co-authored papers 28
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Co-authored papers 26
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MD Anderson Cancer Center
Co-authored papers 22
Huntsman Cancer Institute, University of Utah
Co-authored papers 22
Meyer Cancer Center
Co-authored papers 21
The University of Texas M.D. Anderson Cancer Center
Co-authored papers 19
The University of Texas M.D. Anderson Cancer Center, American University of Beirut
Co-authored papers 16
CIMA-Universidad de Navarra
Co-authored papers 15
University of Virginia School of Medicine
Co-authored papers 14
Greehey Children's Cancer Research Institute
Co-authored papers 13
Yale School of Medicine
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Co-authored papers 11
Ontario Brain Institute
Co-authored papers 10
Knight Cancer Institute, Oregon Health and Sciences University
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Co-authored papers 9
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NYU Grossman School of Medicine
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