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Author Details

Jason S Debley
Seattle Children's Hospital, University of Washington
1996
67
22
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36708815Rhinovirus infection of the airway epithelium enhances mast cell immune responses via epithelial-derived interferons.J Allergy Clin Immunol2023
36993541Tuft cell-derived acetylcholine regulates epithelial fluid secretion.bioRxiv2023
37212596Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in Asthma.Am J Respir Crit Care Med2023
37001649Type 2 inflammation reduces SARS-CoV-2 replication in the airway epithelium in allergic asthma through functional alteration of ciliated epithelial cells.J Allergy Clin Immunol2023
36914406Sputum periostin is a biomarker of type 2 inflammation but not airway dysfunction in asthma.Respirology2023
36469343Call for Papers Reporting Pediatric Translational Science Research.JAMA Pediatr2023
35027395Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma.Eur Respir J2022
35341878Preschool wheeze phenotypes from birth cohorts: Where do we go from here?J Allergy Clin Immunol2022
35484173Airway epithelial interferon response to SARS-CoV-2 is inferior to rhinovirus and heterologous rhinovirus infection suppresses SARS-CoV-2 replication.Sci Rep2022
35938988IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2.J Exp Med2022
36036783Correction: IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2.J Exp Med2022
36198442Temperature synchronisation of circadian rhythms in primary human airway epithelial cells from children.BMJ Open Respir Res2022
35287710Correction to: Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares.Pediatr Rheumatol Online J2022
32511368SwabExpress: An end-to-end protocol for extraction-free COVID-19 testing.bioRxiv2021
33851164Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2.bioRxiv2021
33724365Germline SAMD9L truncation variants trigger global translational repression.J Exp Med2021
34874007Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape.Elife2021
34867390Effect of Angiotensin-Converting-Enzyme Inhibitor and Angiotensin II Receptor Antagonist Treatment on ACE2 Expression and SARS-CoV-2 Replication in Primary Airway Epithelial Cells.Front Pharmacol2021
34779751Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline.Am J Respir Crit Care Med2021
34845445Airway epithelial interferon response to SARS-CoV-2 is inferior to rhinovirus and heterologous rhinovirus infection suppresses SARS-CoV-2 replication.bioRxiv2021
34286830SwabExpress: An End-to-End Protocol for Extraction-Free COVID-19 Testing.Clin Chem2021
33430421Inactivation of Material from SARS-CoV-2-Infected Primary Airway Epithelial Cell Cultures.Methods Protoc2021
33187989Loss of versican and production of hyaluronan in lung epithelial cells are associated with airway inflammation during RSV infection.J Biol Chem2021
32421352Correlation between Ivacaftor-induced CFTR Activation in Airway Epithelial Cells and Improved Lung Function: A Proof-of-Concept Study.Ann Am Thorac Soc2020
32021309Exhaled Nitric Oxide in Wheezy Infants Predicts Persistent Atopic Asthma and Exacerbations at School Age.J Asthma Allergy2020
32047499Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases.Front Immunol2020
32103153Thymic stromal lymphopoietin protects in a model of airway damage and inflammation via regulation of caspase-1 activity and apoptosis inhibition.Mucosal Immunol2020
33097575Juvenile, but Not Adult, Mice Display Increased Myeloid Recruitment and Extracellular Matrix Remodeling during Respiratory Syncytial Virus Infection.J Immunol2020
33178214Cross-Talk Between Alveolar Macrophages and Lung Epithelial Cells is Essential to Maintain Lung Homeostasis.Front Immunol2020
33066778Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares.Pediatr Rheumatol Online J2020
32946274Effects of Asthma and Human Rhinovirus A16 on the Expression of SARS-CoV-2 Entry Factors in Human Airway Epithelium.Am J Respir Cell Mol Biol2020
30969811Infants with evolving bronchopulmonary dysplasia demonstrate monocyte-specific expression of IL-1 in tracheal aspirates.Am J Physiol Lung Cell Mol Physiol2019
31437129Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling.J Clin Invest2019
29106997Interferon response to respiratory syncytial virus by bronchial epithelium from children with asthma is inversely correlated with pulmonary function.J Allergy Clin Immunol2018
30071849Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts.Respir Res2018
29843677Stability of gene expression by primary bronchial epithelial cells over increasing passage number.BMC Pulm Med2018
30361541Fibroblast gene expression following asthmatic bronchial epithelial cell conditioning correlates with epithelial donor lung function and exacerbation history.Sci Rep2018
29394092Deficient Follistatin-like 3 Secretion by Asthmatic Airway Epithelium Impairs Fibroblast Regulation and Fibroblast-to-Myofibroblast Transition.Am J Respir Cell Mol Biol2018
28077237Interplay of extracellular matrix and leukocytes in lung inflammation.Cell Immunol2017
28672068Effect of extending the time after bronchodilator administration on identifying bronchodilator responsiveness in a pediatric pulmonary clinic.Pediatr Pulmonol2017
27022951Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells.J Vis Exp2016
27479061Official American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing.Am J Respir Crit Care Med2016
27126823Subepithelial Accumulation of Versican in a Cockroach Antigen-Induced Murine Model of Allergic Asthma.J Histochem Cytochem2016
25849331Fibroblast-myofibroblast transition is differentially regulated by bronchial epithelial cells from asthmatic children.Respir Res2015
24875618Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components.J Allergy Clin Immunol2014
23576878Respiratory syncytial virus induces functional thymic stromal lymphopoietin receptor in airway epithelial cells.J Inflamm Res2013
24102466Urban particulate matter induces pro-remodeling factors by airway epithelial cells from healthy and asthmatic children.Inhal Toxicol2013
24261945Exhaled nitric oxide predicts persistence of wheezing, exacerbations, and decline in lung function in wheezy infants and toddlers.Clin Exp Allergy2013
22006677Bronchodilator responsiveness in wheezy infants and toddlers is not associated with asthma risk factors.Pediatr Pulmonol2012
22981788Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection.J Allergy Clin Immunol2012
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Collaborators

Center for Immunity and Immunotherapies, Seattle Children's Research Institute
Co-authored papers 19
University of Washington School of Medicine, Seattle Benaroya Research Institute
Co-authored papers 6
University of Washington
Co-authored papers 5
Center for Innate Immunity and Immune Disease, University of Washington
Co-authored papers 3
University of Washington
Co-authored papers 3
Co-authored papers 3
The Rockefeller University
Co-authored papers 2
Institute for Systems Genetics, New York University Langone Medical Center
Co-authored papers 2
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
University of Washington
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
Institute for Systems Genetics, NYU Grossman School of Medicine
Co-authored papers 2
Rockefeller University
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
Center for Global Infectious Disease Research, Seattle Children's Hospital
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Octant Inc.
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
The Rockefeller University, St John's University
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
Center for Global Infectious Disease Research, Seattle Children's Research Institute
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
University of Washington
Co-authored papers 2
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University of Washington, Seattle Children's Hospital
Co-authored papers 2
University of California San Francisco
Co-authored papers 2
Center for Global Infectious Disease Research, Seattle Children's Hospital
Co-authored papers 2