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Author Details
Full Name
Jason S Debley
Affiliation
Seattle Children's Hospital, University of Washington
ORCID
Career Start Year
1996
Papers
67
H Index
22
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36708815
Rhinovirus infection of the airway epithelium enhances mast cell immune responses via epithelial-derived interferons.
J Allergy Clin Immunol
2023
36993541
Tuft cell-derived acetylcholine regulates epithelial fluid secretion.
bioRxiv
2023
37212596
Distinct Epithelial-Innate Immune Cell Transcriptional Circuits Underlie Airway Hyperresponsiveness in Asthma.
Am J Respir Crit Care Med
2023
37001649
Type 2 inflammation reduces SARS-CoV-2 replication in the airway epithelium in allergic asthma through functional alteration of ciliated epithelial cells.
J Allergy Clin Immunol
2023
36914406
Sputum periostin is a biomarker of type 2 inflammation but not airway dysfunction in asthma.
Respirology
2023
36469343
Call for Papers Reporting Pediatric Translational Science Research.
JAMA Pediatr
2023
35027395
Location of eosinophils in the airway wall is critical for specific features of airway hyperresponsiveness and T2 inflammation in asthma.
Eur Respir J
2022
35341878
Preschool wheeze phenotypes from birth cohorts: Where do we go from here?
J Allergy Clin Immunol
2022
35484173
Airway epithelial interferon response to SARS-CoV-2 is inferior to rhinovirus and heterologous rhinovirus infection suppresses SARS-CoV-2 replication.
Sci Rep
2022
35938988
IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2.
J Exp Med
2022
36036783
Correction: IgM antibodies derived from memory B cells are potent cross-variant neutralizers of SARS-CoV-2.
J Exp Med
2022
36198442
Temperature synchronisation of circadian rhythms in primary human airway epithelial cells from children.
BMJ Open Respir Res
2022
35287710
Correction to: Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares.
Pediatr Rheumatol Online J
2022
32511368
SwabExpress: An end-to-end protocol for extraction-free COVID-19 testing.
bioRxiv
2021
33851164
Nanobody Repertoires for Exposing Vulnerabilities of SARS-CoV-2.
bioRxiv
2021
33724365
Germline SAMD9L truncation variants trigger global translational repression.
J Exp Med
2021
34874007
Highly synergistic combinations of nanobodies that target SARS-CoV-2 and are resistant to escape.
Elife
2021
34867390
Effect of Angiotensin-Converting-Enzyme Inhibitor and Angiotensin II Receptor Antagonist Treatment on ACE2 Expression and SARS-CoV-2 Replication in Primary Airway Epithelial Cells.
Front Pharmacol
2021
34779751
Use of Fractional Exhaled Nitric Oxide to Guide the Treatment of Asthma: An Official American Thoracic Society Clinical Practice Guideline.
Am J Respir Crit Care Med
2021
34845445
Airway epithelial interferon response to SARS-CoV-2 is inferior to rhinovirus and heterologous rhinovirus infection suppresses SARS-CoV-2 replication.
bioRxiv
2021
34286830
SwabExpress: An End-to-End Protocol for Extraction-Free COVID-19 Testing.
Clin Chem
2021
33430421
Inactivation of Material from SARS-CoV-2-Infected Primary Airway Epithelial Cell Cultures.
Methods Protoc
2021
33187989
Loss of versican and production of hyaluronan in lung epithelial cells are associated with airway inflammation during RSV infection.
J Biol Chem
2021
32421352
Correlation between Ivacaftor-induced CFTR Activation in Airway Epithelial Cells and Improved Lung Function: A Proof-of-Concept Study.
Ann Am Thorac Soc
2020
32021309
Exhaled Nitric Oxide in Wheezy Infants Predicts Persistent Atopic Asthma and Exacerbations at School Age.
J Asthma Allergy
2020
32047499
Respiratory Syncytial Virus Infection of Human Lung Fibroblasts Induces a Hyaluronan-Enriched Extracellular Matrix That Binds Mast Cells and Enhances Expression of Mast Cell Proteases.
Front Immunol
2020
32103153
Thymic stromal lymphopoietin protects in a model of airway damage and inflammation via regulation of caspase-1 activity and apoptosis inhibition.
Mucosal Immunol
2020
33097575
Juvenile, but Not Adult, Mice Display Increased Myeloid Recruitment and Extracellular Matrix Remodeling during Respiratory Syncytial Virus Infection.
J Immunol
2020
33178214
Cross-Talk Between Alveolar Macrophages and Lung Epithelial Cells is Essential to Maintain Lung Homeostasis.
Front Immunol
2020
33066778
Heme oxygenase-1 deficiency presenting with interstitial lung disease and hemophagocytic flares.
Pediatr Rheumatol Online J
2020
32946274
Effects of Asthma and Human Rhinovirus A16 on the Expression of SARS-CoV-2 Entry Factors in Human Airway Epithelium.
Am J Respir Cell Mol Biol
2020
30969811
Infants with evolving bronchopulmonary dysplasia demonstrate monocyte-specific expression of IL-1 in tracheal aspirates.
Am J Physiol Lung Cell Mol Physiol
2019
31437129
Airway epithelium-shifted mast cell infiltration regulates asthmatic inflammation via IL-33 signaling.
J Clin Invest
2019
29106997
Interferon response to respiratory syncytial virus by bronchial epithelium from children with asthma is inversely correlated with pulmonary function.
J Allergy Clin Immunol
2018
30071849
Asthmatic bronchial epithelial cells promote the establishment of a Hyaluronan-enriched, leukocyte-adhesive extracellular matrix by lung fibroblasts.
Respir Res
2018
29843677
Stability of gene expression by primary bronchial epithelial cells over increasing passage number.
BMC Pulm Med
2018
30361541
Fibroblast gene expression following asthmatic bronchial epithelial cell conditioning correlates with epithelial donor lung function and exacerbation history.
Sci Rep
2018
29394092
Deficient Follistatin-like 3 Secretion by Asthmatic Airway Epithelium Impairs Fibroblast Regulation and Fibroblast-to-Myofibroblast Transition.
Am J Respir Cell Mol Biol
2018
28077237
Interplay of extracellular matrix and leukocytes in lung inflammation.
Cell Immunol
2017
28672068
Effect of extending the time after bronchodilator administration on identifying bronchodilator responsiveness in a pediatric pulmonary clinic.
Pediatr Pulmonol
2017
27022951
Cultivate Primary Nasal Epithelial Cells from Children and Reprogram into Induced Pluripotent Stem Cells.
J Vis Exp
2016
27479061
Official American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing.
Am J Respir Crit Care Med
2016
27126823
Subepithelial Accumulation of Versican in a Cockroach Antigen-Induced Murine Model of Allergic Asthma.
J Histochem Cytochem
2016
25849331
Fibroblast-myofibroblast transition is differentially regulated by bronchial epithelial cells from asthmatic children.
Respir Res
2015
24875618
Asthmatic airway epithelial cells differentially regulate fibroblast expression of extracellular matrix components.
J Allergy Clin Immunol
2014
23576878
Respiratory syncytial virus induces functional thymic stromal lymphopoietin receptor in airway epithelial cells.
J Inflamm Res
2013
24102466
Urban particulate matter induces pro-remodeling factors by airway epithelial cells from healthy and asthmatic children.
Inhal Toxicol
2013
24261945
Exhaled nitric oxide predicts persistence of wheezing, exacerbations, and decline in lung function in wheezy infants and toddlers.
Clin Exp Allergy
2013
22006677
Bronchodilator responsiveness in wheezy infants and toddlers is not associated with asthma risk factors.
Pediatr Pulmonol
2012
22981788
Thymic stromal lymphopoietin is induced by respiratory syncytial virus-infected airway epithelial cells and promotes a type 2 response to infection.
J Allergy Clin Immunol
2012
1 - 50 of 67
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Co-authored papers
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Michael Gale
Center for Innate Immunity and Immune Disease, University of Washington
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Michael J Bamshad
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3
Sina A Gharib
Co-authored papers
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The Rockefeller University
Co-authored papers
2
Sarah Keegan
Institute for Systems Genetics, New York University Langone Medical Center
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John D Aitchison
Center for Global Infectious Disease Research, Seattle Children's Research Institute
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Paul Dominic B Olinares
The Rockefeller University
Co-authored papers
2
Jay Shendure
University of Washington
Co-authored papers
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Paul D Bieniasz
The Rockefeller University
Co-authored papers
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David Feny??
Institute for Systems Genetics, NYU Grossman School of Medicine
Co-authored papers
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Yiska Weisblum
Rockefeller University
Co-authored papers
2
Theodora Hatziioannou
The Rockefeller University
Co-authored papers
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Vladimir Vigdorovich
Center for Global Infectious Disease Research, Seattle Children's Hospital
Co-authored papers
2
Tanmoy Sanyal
University of California san francisco
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Sriram Kosuri
Octant Inc.
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Peter C Fridy
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