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Author Details

Robert E Denroche
Ontario Institute for Cancer Research
2012
43
21
PMIDPaper TitleJournal TitlePublished Year
34583947Molecular characterisation of pancreatic ductal adenocarcinoma with <i>NTRK</i> fusions and review of the literature.J Clin Pathol2023
37449843Spectrum of Response to Platinum and PARP Inhibitors in Germline BRCA-Associated Pancreatic Cancer in the Clinical and Preclinical Setting.Cancer Discov2023
36915452Whole-genome sequencing of 20 cholangiocarcinoma cases reveals unique profiles in patients with cirrhosis and primary sclerosing cholangitis.J Gastrointest Oncol2023
36222851hENT1 Expression Predicts Response to Gemcitabine and Nab-Paclitaxel in Advanced Pancreatic Ductal Adenocarcinoma.Clin Cancer Res2022
35547873Intra-Tumoral CD8+ T-Cell Infiltration and PD-L1 Positivity in Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma.Front Oncol2022
35694787Correction: GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer.Clin Cancer Res2022
35714671Is Biannual Surveillance for Pancreatic Cancer Sufficient in Individuals With Genetic Syndromes or Familial Pancreatic Cancer?J Natl Compr Canc Netw2022
36417526Widespread hypertranscription in aggressive human cancers.Sci Adv2022
36209277Integrative analysis of KRAS wildtype metastatic pancreatic ductal adenocarcinoma reveals mutation and expression-based similarities to cholangiocarcinoma.Nat Commun2022
32958704Delving into Early-onset Pancreatic Ductal Adenocarcinoma: How Does Age Fit In?Clin Cancer Res2021
33524400Genomic Features and Classification of Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma.Gastroenterology2021
34644529Spatially confined sub-tumor microenvironments in pancreatic cancer.Cell2021
34011980Patient-derived tumor xenograft and organoid models established from resected pancreatic, duodenal and biliary cancers.Sci Rep2021
33051307Subtype-Discordant Pancreatic Ductal Adenocarcinoma Tumors Show Intermediate Clinical and Molecular Characteristics.Clin Cancer Res2021
32933947Clinical and genomic characterisation of mismatch repair deficient pancreatic adenocarcinoma.Gut2021
31481506Altered Gene Expression along the Glycolysis-Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer.Clin Cancer Res2020
31964786A Four-Chemokine Signature Is Associated with a T-cell-Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer.Clin Cancer Res2020
31932696Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.Nat Genet2020
32051610Author Correction: Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution.Nat Genet2020
32816949A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination-deficient Pancreatic Cancer.Clin Cancer Res2020
32518206Endogenous Retrovirus Transcript Levels Are Associated with Immunogenic Signatures in Multiple Metastatic Cancer Types.Mol Cancer Ther2020
32156747GATA6 Expression Distinguishes Classical and Basal-like Subtypes in Advanced Pancreatic Cancer.Clin Cancer Res2020
30686769Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases.Cancer Cell2019
31070984Meta-Analysis of 1,200 Transcriptomic Profiles Identifies a Prognostic Model for Pancreatic Ductal Adenocarcinoma.JCO Clin Cancer Inform2019
31068372<i>NRG1</i> Gene Fusions Are Recurrent, Clinically Actionable Gene Rearrangements in <i>KRAS</i> Wild-Type Pancreatic Ductal Adenocarcinoma.Clin Cancer Res2019
30629588Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer.PLoS Comput Biol2019
29288237Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial.Clin Cancer Res2018
29853643Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.Cancer Discov2018
29378198Mutations in Mitochondrial DNA From Pancreatic Ductal Adenocarcinomas Associate With Survival Times of Patients and Accumulate as Tumors Progress.Gastroenterology2018
29396858Recapitulating the clinical scenario of BRCA-associated pancreatic cancer in pre-clinical models.Int J Cancer2018
29074453Exome-Wide Association Study of Pancreatic Cancer Risk.Gastroenterology2018
28068672Genomic hallmarks of localized, non-indolent prostate cancer.Nature2017
28489577Pancreatic cancer ascites xenograft-an expeditious model mirroring advanced therapeutic resistant disease.Oncotarget2017
27851734Erratum: A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2017
27768182Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma.JAMA Oncol2017
27732578A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns.Nature2016
26590902Fine mapping of chromosome 5p15.33 based on a targeted deep sequencing and high density genotyping identifies novel lung cancer susceptibility loci.Carcinogenesis2016
26005866Spatial genomic heterogeneity within localized, multifocal prostate cancer.Nat Genet2015
26647970A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.Nat Commun2015
26708082A cancer cell-line titration series for evaluating somatic classification.BMC Res Notes2015
24728235A two-dimensional pooling strategy for rare variant detection on next-generation sequencing platforms.PLoS One2014
25173705SeqControl: process control for DNA sequencing.Nat Methods2014
23103869Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.Nature2012
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Ontario Institute for Cancer Research
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Faiyaz Notta
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Co-authored papers 11
John D McPherson
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Mathieu Lemire
The Hospital for Sick Children
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Andrew J Mungall
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Paul M Krzyzanowski
Ontario Institute for Cancer Research
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Richard A Moore
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Andrew M K Brown
Ontario Institute for Cancer Research
Co-authored papers 5
Gloria M Petersen
Mayo Clinic
Co-authored papers 5
Thomas J Hudson
Ontario Institute for Cancer Research
Co-authored papers 5
Peter J Campbell
Wellcome Sanger Institute
Co-authored papers 5
Paul C Boutros
University of California los angeles
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Ming-Sound Tsao
University Health Network, University of Toronto
Co-authored papers 5
Nicholas Buchner
Ontario Institute for Cancer Research
Co-authored papers 5
Steve E Kalloger
University of British Columbia
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Jeremy Johns
Rutgers Robert Wood Johnson Medical School
Co-authored papers 4
Lawrence E Heisler
Ontario Institute for Cancer Research
Co-authored papers 4
Mehdi Masoomian
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Release 1.2