Author details

Full Name

Josep M Mercader

Affiliation

ORCID

Career Start Year

1972

Papers

182

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36525397	Identification of Genetic Variation Influencing Metformin Response in a Multiancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP).	Diabetes	2023
37841955	A Type 1 Diabetes Polygenic Score Is Not Associated With Prevalent Type 2 Diabetes in Large Population Studies.	J Endocr Soc	2023
37808749	Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity.	medRxiv	2023
37808701	Rare variant association analysis in 51,256 type 2 diabetes cases and 370,487 controls informs the spectrum of pathogenicity of monogenic diabetes genes.	medRxiv	2023
37732265	Algorithms for the identification of prevalent diabetes in the All of Us Research Program validated using polygenic scores - a new resource for diabetes precision medicine.		2023
37732255	Polygenic Scores for Longitudinal Prediction of Incident Type 2 Diabetes in an Ancestrally and Medically Diverse Primary Care Network.		2023
37886436	Multi-ancestry Polygenic Mechanisms of Type 2 Diabetes Elucidate Disease Processes and Clinical Heterogeneity.	Res Sq	2023
37148359	The power of TOPMed imputation for the discovery of Latino-enriched rare variants associated with type 2 diabetes.	Diabetologia	2023
36745605	Polygenic Scores Help Reduce Racial Disparities in Predictive Accuracy of Automated Type 1 Diabetes Classification Algorithms.		2023
36538063	High-throughput genetic clustering of type 2 diabetes loci reveals heterogeneous mechanistic pathways of metabolic disease.		2023
37353344	Type 2 Diabetes Polygenic Score Predicts the Risk of Glucocorticoid-Induced Hyperglycemia in Patients Without Diabetes.		2023
37292813	Insights from rare variants into the genetic architecture and biology of youth-onset type 2 diabetes.	Res Sq	2023
36787958	Association and Interaction of Genetics and Area-Level Socioeconomic Factors on the Prevalence of Type 2 Diabetes and Obesity.	Diabetes Care	2023
37546893	Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People with Type 2 Diabetes Mellitus.	medRxiv	2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
35349657	Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682.	Diabetes Care	2022
35948088	Mendelian Randomization Shows a Causal Effect of Low Vitamin D on Non-infectious Uveitis and Scleritis Risk.	Am J Ophthalmol	2022
35864532	Proteomic analysis of cardiometabolic biomarkers and predictive modeling of severe outcomes in patients hospitalized with COVID-19.	Cardiovasc Diabetol	2022
35677078	Proteomic analysis of cardiometabolic biomarkers and predictive modeling of severe outcomes in patients hospitalized with COVID-19.	Res Sq	2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
35723666	Association of GLP1R Polymorphisms With the Incretin Response.	Journal of Clinical Endocrinology and Metabolism	2022
35399580	Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits-The Hispanic/Latino Anthropometry Consortium.	HGG Adv	2022
36508462	Algorithmic identification of atypical diabetes in electronic health record (EHR) systems.		2022
34862199	Recessive Genome-Wide Meta-analysis Illuminates Genetic Architecture of Type 2 Diabetes.	Diabetes	2022
34789503	Obesity Partially Mediates the Diabetogenic Effect of Lowering LDL Cholesterol.	Diabetes Care	2022
35085396	Type 2 Diabetes Partitioned Polygenic Scores Associate With Disease Outcomes in 454,193 Individuals Across 13 Cohorts.	Diabetes Care	2022
34644572	TIGER: The gene expression regulatory variation landscape of human pancreatic islets.	Cell Rep	2021
33479058	The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium.	Diabetes	2021
33893285	The impact of non-additive genetic associations on age-related complex diseases.	Nat Commun	2021
34108472	Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.	Nat Commun	2021
33661905	Cardiometabolic risk factors for COVID-19 susceptibility and severity: A Mendelian randomization analysis.	PLoS Medicine	2021
33987664	Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations.	Hum Mol Genet	2021
33822779	Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.	PLoS Genet	2021
34717821	Predicting diabetes risk in diverse populations: what next?	Lancet Diabetes and Endocrinology,The	2021
34607834	Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas.	Diabetes Care	2021
34604815	Genetic discovery and risk characterization in type 2 diabetes across diverse populations.	HGG Adv	2021
32909013	Cardiometabolic Risk Factors for COVID-19 Susceptibility and Severity: A Mendelian Randomization Analysis.		2020
32470372	Polymorphic Inversions Underlie the Shared Genetic Susceptibility of Obesity-Related Diseases.	Am J Hum Genet	2020
32467615	Integrating untargeted metabolomics, genetically informed causal inference, and pathway enrichment to define the obesity metabolome.	Int J Obes (Lond)	2020
33150273	Analysis of Glucocorticoid-Related Genes Reveal as a New Candidate Gene for Type 2 Diabetes.	Journal of the Endocrine Society	2020
31145872	Cytoskeletal transgelin 2 contributes to gender-dependent adipose tissue expandability and immune function.	FASEB Journal	2019
31560688	Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain.	PLoS One	2019
30552173	Genetic variation at the glycosaminoglycan metabolism pathway contributes to the risk of psoriatic arthritis but not psoriasis.	Ann Rheum Dis	2019
30640898	PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data.	PLoS Comput Biol	2019
31428720	A Polygenic Lipodystrophy Genetic Risk Score Characterizes Risk Independent of BMI in the Diabetes Prevention Program.	J Endocr Soc	2019
31253982	Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.	Nat Genet	2019
29358691	Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.	Nat Commun	2018
30166351	Multitrait genome association analysis identifies new susceptibility genes for human anthropometric variation in the GCAT cohort.	J Med Genet	2018
30116036	Author Correction: Genome-wide association and HLA fine-mapping studies identify risk loci and genetic pathways underlying allergic rhinitis.	Nat Genet	2018
30207284	Genomic profiling in advanced stage non-small-cell lung cancer patients with platinum-based chemotherapy identifies germline variants with prognostic value in SMYD2.	Cancer Treat Res Commun	2018