Author details

Full Name

John J Sninsky

Affiliation

ORCID

Career Start Year

1974

Papers

122

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37219869	Circulating cell-free messenger RNA secretome characterization of primary sclerosing cholangitis.	Hepatol Commun	2023
36054939	Survey of extracellular communication of systemic and organ-specific inflammatory responses through cell free messenger RNA profiling in mice.	EBioMedicine	2022
36323792	The Coronavirus Standards Working Group's roadmap for improved population testing.	Nat Biotechnol	2022
33501884	Noninvasive stratification of nonalcoholic fatty liver disease by whole transcriptome cell-free mRNA characterization.	Am J Physiol Gastrointest Liver Physiol	2021
30234148	Donor-derived Cell-free DNA Identifies Antibody-mediated Rejection in Donor Specific Antibody Positive Kidney Transplant Recipients.	Transplantation Direct	2018
28280140	Cell-Free DNA and Active Rejection in Kidney Allografts.	J Am Soc Nephrol	2017
33636851	Biological Variation of Donor-Derived Cell-Free DNA in Renal Transplant Recipients: Clinical Implications.	J Appl Lab Med	2017
27727019	Validation of a Clinical-Grade Assay to Measure Donor-Derived Cell-Free DNA in Solid Organ Transplant Recipients.	Journal of Molecular Diagnostics	2016
27391584	Risk Factors for Hepatocellular Carcinoma in Cirrhotic Patients with Chronic Hepatitis B.	Genetic Testing and Molecular Biomarkers	2016
27084556	Mutation Yield of a 34-Gene Solid Tumor Panel in Community-Based Tumor Samples.		2016
26672634	Hepatic Steatosis and Insulin Resistance, But Not Steatohepatitis, Promote Atherogenic Dyslipidemia in NAFLD.	Journal of Clinical Endocrinology and Metabolism	2016
25926090	Cost Effectiveness of Sequencing 34 Cancer-Associated Genes as an Aid for Treatment Selection in Patients with Metastatic Melanoma.		2015
24917882	Genetic-based prediction of disease traits: prediction is very difficult, especially about the future.	Front Genet	2014
24172169	An optimized five-gene multi-platform predictor of hormone receptor negative and triple negative breast cancer metastatic risk.	Breast Cancer Res	2013
23844940	A candidate gene study for the association of host single nucleotide polymorphisms with liver cirrhosis risk in chinese hepatitis B patients.	Genetic Testing and Molecular Biomarkers	2013
23838699	Classification of LDL phenotypes by 4 methods of determining lipoprotein particle size.	Journal of Investigative Medicine	2013
23028762	Multiple metabolic alterations exist in mutant PI3K cancers, but only glucose is essential as a nutrient source.	PLoS ONE	2012
21830102	Genetic testing for early detection of individuals at risk of coronary heart disease and monitoring response to therapy: challenges and promises.	Current Atherosclerosis Reports	2011
21488075	Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C.	Hepatology	2011
21440548	A functional polymorphism in the epidermal growth factor gene is associated with risk for hepatocellular carcinoma.	Gastroenterology	2011
21145859	Role of a cirrhosis risk score for the early prediction of fibrosis progression in hepatitis C patients with minimal liver disease.	Journal of Hepatology	2011
21586232	[Polymorphism of ornithine decarboxylase antizyme inhibitor 1 gene is associated with liver cirrhosis in Chinese hepatitis B patients].	Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology	2011
21760886	An IL28B genotype-based clinical prediction model for treatment of chronic hepatitis C.	PLoS One	2011
21837750	A polymorphism that delays fibrosis in hepatitis C promotes alternative splicing of AZIN1, reducing fibrogenesis.	Hepatology	2011
21946897	Predicting cirrhosis and clinical outcomes in patients with advanced chronic hepatitis C with a panel of genetic markers (CRS7).	Pharmacogenetics and Genomics	2011
20022962	A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells.	J Biol Chem	2010
20946665	A multigene predictor of metastatic outcome in early stage hormone receptor-negative and triple-negative breast cancer.	Breast Cancer Res	2010
19225135	A single-tube quantitative assay for mRNA levels of hormonal and growth factor receptors in breast cancer specimens.	Journal of Molecular Diagnostics	2009
19085953	Functional linkage of cirrhosis-predictive single nucleotide polymorphisms of Toll-like receptor 4 to hepatic stellate cell responses.	Hepatology	2009
19586676	Multiple variants in toll-like receptor 4 gene modulate risk of liver fibrosis in Caucasians with chronic hepatitis C infection.	Journal of Hepatology	2009
19662163	Evolutionary processes acting on candidate cis-regulatory regions in humans inferred from patterns of polymorphism and divergence.	PLoS Genet	2009
18288194	Proportionally more deleterious genetic variation in European than in African populations.	Nature	2008
19025599	Risk estimation of distant metastasis in node-negative, estrogen receptor-positive breast cancer patients using an RT-PCR based prognostic expression signature.	BMC Cancer	2008
18516229	Assessing the evolutionary impact of amino acid mutations in the human genome.	PLoS Genet	2008
17360557	Haplotype structure and selection of the MDM2 oncogene in humans.	Proc Natl Acad Sci U S A	2007
17461418	A 7 gene signature identifies the risk of developing cirrhosis in patients with chronic hepatitis C.	Hepatology	2007
17317784	Evidence for novel susceptibility genes for late-onset Alzheimer's disease from a genome-wide association study of putative functional variants.	Hum Mol Genet	2007
16385451	A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.	Am J Hum Genet	2006
17243484	Polymorphisms associated with coronary heart disease: better by the score.	Current Opinion in Molecular Therapeutics	2006
16697732	Identification of two gene variants associated with risk of advanced fibrosis in patients with chronic hepatitis C.	Gastroenterology	2006
16685663	A case-control association study of the 12 single-nucleotide polymorphisms implicated in Parkinson disease by a recent genome scan.	Am J Hum Genet	2006
16237444	Natural selection on protein-coding genes in the human genome.	Nature	2005
15714520	Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease.	Hum Mutat	2005
15869325	A scan for positively selected genes in the genomes of humans and chimpanzees.	PLoS Biol	2005
15970929	The BDNF Val66Met polymorphism is not associated with late onset Alzheimer's disease in three case-control samples.	Mol Psychiatry	2005
16175505	Identification of four gene variants associated with myocardial infarction.	Am J Hum Genet	2005
15088270	A high-density admixture map for disease gene discovery in african americans.	Am J Hum Genet	2004
15288432	Association of ABCA1 with late-onset Alzheimer's disease is not observed in a case-control study.	Neurosci Lett	2004
15507493	Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family.	Proc Natl Acad Sci U S A	2004
15208781	A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis.	Am J Hum Genet	2004