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Author Details

Alexei Protopopov
The University of MD Anderson Cancer Center
1995
108
53
PMIDPaper TitleJournal TitlePublished Year
35138907A functional genomic approach to actionable gene fusions for precision oncology.Sci Adv2022
35138907A functional genomic approach to actionable gene fusions for precision oncology.Sci Adv2022
33224628Pan-TGFβ inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade.Oncoimmunology2020
33224628Pan-TGFβ inhibition by SAR439459 relieves immunosuppression and improves antitumor efficacy of PD-1 blockade.Oncoimmunology2020
31610796Global impact of somatic structural variation on the DNA methylome of human cancers.Genome Biol2019
31610796Global impact of somatic structural variation on the DNA methylome of human cancers.Genome Biol2019
29686388Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma.Nat Genet2018
29996110A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases.Cell Rep2018
29903896Dual MAPK Inhibition Is an Effective Therapeutic Strategy for a Subset of Class II BRAF Mutant Melanomas.Clin Cancer Res2018
29642553Genomic Profiling on an Unselected Solid Tumor Population Reveals a Highly Mutated Wnt/β-Catenin Pathway Associated with Oncogenic EGFR Mutations.J Pers Med2018
29686388Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma.Nat Genet2018
29996110A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases.Cell Rep2018
29903896Dual MAPK Inhibition Is an Effective Therapeutic Strategy for a Subset of Class II BRAF Mutant Melanomas.Clin Cancer Res2018
29642553Genomic Profiling on an Unselected Solid Tumor Population Reveals a Highly Mutated Wnt/β-Catenin Pathway Associated with Oncogenic EGFR Mutations.J Pers Med2018
28890729Clinical application of a cancer genomic profiling assay to guide precision medicine decisions.Per Med2017
28890729Clinical application of a cancer genomic profiling assay to guide precision medicine decisions.Per Med2017
28445736Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression.Cell Rep2017
28528867A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.Cancer Cell2017
28698296PRKCI promotes immune suppression in ovarian cancer.Genes Dev2017
28514651Modeling Genomic Instability and Selection Pressure in a Mouse Model of Melanoma.Cell Rep2017
29212173Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.Oncotarget2017
28235632Utility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer.Hum Pathol2017
28445736Systematic Epigenomic Analysis Reveals Chromatin States Associated with Melanoma Progression.Cell Rep2017
28235632Utility of comprehensive genomic sequencing for detecting HER2-positive colorectal cancer.Hum Pathol2017
29212173Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer.Oncotarget2017
28514651Modeling Genomic Instability and Selection Pressure in a Mouse Model of Melanoma.Cell Rep2017
28698296PRKCI promotes immune suppression in ovarian cancer.Genes Dev2017
28528867A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.Cancer Cell2017
28007036Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine.Genome Med2016
28007036Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine.Genome Med2016
25583766Identification of a novel fusion gene, IRF2BP2-RARA, in acute promyelocytic leukemia.J Natl Compr Canc Netw2015
25705882Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.J Clin Invest2015
25583766Identification of a novel fusion gene, IRF2BP2-RARA, in acute promyelocytic leukemia.J Natl Compr Canc Netw2015
25938254Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer.J Vis Exp2015
26139243The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies.Cancer Res2015
26061751Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.N Engl J Med2015
26061751Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.N Engl J Med2015
26139243The SMARCA2/4 ATPase Domain Surpasses the Bromodomain as a Drug Target in SWI/SNF-Mutant Cancers: Insights from cDNA Rescue and PFI-3 Inhibitor Studies.Cancer Res2015
25938254Utilizing murine inducible telomerase alleles in the studies of tissue degeneration/regeneration and cancer.J Vis Exp2015
25705882Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma.J Clin Invest2015
24398677Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer.J Biol Chem2014
25313082Characterization of HPV and host genome interactions in primary head and neck cancers.Proc Natl Acad Sci U S A2014
25352948Telomere dysfunction suppresses multiple endocrine neoplasia in mice.Genes Cancer2014
25301631Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing.Science2014
24398677Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer.J Biol Chem2014
24954535Yap1 activation enables bypass of oncogenic Kras addiction in pancreatic cancer.Cell2014
24633157Recurrent PTPRB and PLCG1 mutations in angiosarcoma.Nat Genet2014
25301631Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing.Science2014
25313082Characterization of HPV and host genome interactions in primary head and neck cancers.Proc Natl Acad Sci U S A2014
25352948Telomere dysfunction suppresses multiple endocrine neoplasia in mice.Genes Cancer2014
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Collaborators

Eugene R Zabarovsky
Co-authored papers 38
Lynda Chin
Co-authored papers 35
Jianhua Zhang
University of Texas MD Anderson Cancer Center
Co-authored papers 19
Elena Ivanova
Dana-Farber Cancer Institute
Co-authored papers 14
Sahil Seth
The University of Texas MD Anderson Cancer Center
Co-authored papers 12
Harshad S Mahadeshwar
The University of MD Anderson Cancer Center
Co-authored papers 10
Maria Kost-Alimova
Co-authored papers 10
Bin Feng
The First Affiliated Hospital of Jinan University
Co-authored papers 10
Claes Wahlestedt
Co-authored papers 9
Cameron Brennan
Co-authored papers 9
Xiaojia Ren
University of Kentucky College of Medicine
Co-authored papers 9
Phillip A Futreal
The University of Texas MD Anderson Cancer Center
Co-authored papers 9
Jiabin Tang
The University of MD Anderson Cancer Center
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Xingzhi Song
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Raju Kucherlapati
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TESARO Inc.
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Angela Hadjipanayis
Harvard Medical School, Brigham and Women's Hospital
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Jonathan G Seidman
Harvard Medical School
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Angeliki Pantazi
Harvard Medical School, Brigham and Women's Hospital
Co-authored papers 7
Christopher A Bristow
The University of Texas MD Anderson Cancer Center
Co-authored papers 7
Yaoqi Alan Wang
The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Semin Lee
Ulsan National Institute of Science and Technology (UNIST)
Co-authored papers 6
Peter J Park
Harvard Medical School
Co-authored papers 6
John D Minna
University of Texas Southwestern Medical Center at Dallas
Co-authored papers 5
Kenneth C Anderson
Dana Farber Cancer Institute
Co-authored papers 5
Alex Look
Dana-Farber Cancer Institute
Co-authored papers 5
Lynda Chin
The University of MD Anderson Cancer Center
Co-authored papers 5
Huandong Sun
Co-authored papers 5
Timothy P Heffernan
Co-authored papers 5
Release 1.2