Author details

Full Name

Cankut Ã¿ubuk

Affiliation

ORCID

Career Start Year

2013

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37108611	Crosstalk between Metabolite Production and Signaling Activity in Breast Cancer.	Int J Mol Sci	2023
37979960	Expression quantitative trait loci analysis in rheumatoid arthritis identifies tissue specific variants associated with severity and outcome.		2023
37318951	Defective extracellular matrix remodeling in brown adipose tissue is associated with fibro-inflammation and reduced diet-induced thermogenesis.		2023
34987094	Role of synovial fibroblast subsets across synovial pathotypes in rheumatoid arthritis: a deconvolution analysis.	RMD Open	2022
33208383	Combining evidence for and against pathogenicity for variants in cancer susceptibility genes: CanVIG-UK consensus recommendations.	J Med Genet	2021
34230640	Clinical likelihood ratios and balanced accuracy for 44 in silico tools against multiple large-scale functional assays of cancer susceptibility genes.	Genet Med	2021
33478554	Mechanistic modeling of the SARS-CoV-2 disease map.	BioData Min	2021
34136096	Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data.	Comput Struct Biotechnol J	2021
34030623	Taxonomic variations in the gut microbiome of gout patients with and without tophi might have a functional impact on urate metabolism.	Mol Med	2021
32610626	Mechanistic Models of Signaling Pathways Reveal the Drug Action Mechanisms behind Gender-Specific Gene Expression for Cancer Treatments.	Cells	2020
31418690	Accelerated phosphatidylcholine turnover in macrophages promotes adipose tissue inflammation in obesity.	Elife	2019
29868818	A comparison of mechanistic signaling pathway activity analysis methods.	Brief Bioinform	2019
30854222	Differential metabolic activity and discovery of therapeutic targets using summarized metabolic pathway models.	NPJ Syst Biol Appl	2019
29440659	The effects of death and post-mortem cold ischemia on human tissue transcriptomes.	Nat Commun	2018
30135189	Gene Expression Integration into Pathway Modules Reveals a Pan-Cancer Metabolic Landscape.	Cancer Res	2018
30134948	Models of cell signaling uncover molecular mechanisms of high-risk neuroblastoma and predict disease outcome.	Biol Direct	2018
28042959	High throughput estimation of functional cell activities reveals disease mechanisms and predicts relevant clinical outcomes.	Oncotarget	2017
28961772	Reference genome assessment from a population scale perspective: an accurate profile of variability and noise.	Bioinformatics	2017
26946982	Chronic subordination stress selectively downregulates the insulin signaling pathway in liver and skeletal muscle but not in adipose tissue of male mice.	Stress	2016
27137885	Actionable pathways: interactive discovery of therapeutic targets using signaling pathway models.	Nucleic Acids Res	2016
26844204	Stress-induced activation of brown adipose tissue prevents obesity in conditions of low adaptive thermogenesis.	Mol Metab	2015
25897133	Babelomics 5.0: functional interpretation for new generations of genomic data.	Nucleic Acids Res	2015
23570624	Tissue expression of MLH1, PMS2, MSH2, and MSH6 proteins and prognostic value of microsatellite instability in Wilms tumor: experience of 45 cases.	Pediatric Hematology and Oncology	2013