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Author Details

Zhandong Liu
Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital
2003
115
36
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36865102SPA-STOCSY: An Automated Tool for Identification of Annotated and Non-Annotated Metabolites in High-Throughput NMR Spectra.bioRxiv2023
37704727A cross-species proteomic map reveals neoteny of human synapse development.Nature2023
37741276Literature-based predictions of Mendelian disease therapies.Am J Hum Genet2023
37219079Tau polarizes an aging transcriptional signature to excitatory neurons and glia.Elife2023
36991331Correction: Single-cell multi-omics integration for unpaired data by a siamese network with graph-based contrastive loss.BMC Bioinformatics2023
36982190A Comprehensive and Integrative Approach to MeCP2 Disease Transcriptomics.Int J Mol Sci2023
36976514Loss of the Maternal Effect Gene Nlrp2 Alters the Transcriptome of Ovulated Mouse Oocytes and Impacts Expression of Histone Demethylase KDM1B.Reprod Sci2023
37436699Unravelling spatial gene associations with SEAGAL: a Python package for spatial transcriptomics data analysis and visualization.Bioinformatics2023
36924764Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1.Neuron2023
36747700PolyAMiner-Bulk: A Machine Learning Based Bioinformatics Algorithm to Infer and Decode Alternative Polyadenylation Dynamics from bulk RNA-seq data.bioRxiv2023
36747664scGREAT: Graph-based regulatory element analysis tool for single-cell multi-omics data.bioRxiv2023
36848184MeCP2 regulates <i>Gdf11</i>, a dosage-sensitive gene critical for neurological function.Elife2023
36610398Evolutionarily conserved regulators of tau identify targets for new therapies.Neuron2023
36577402Disruption of the ATXN1-CIC complex reveals the role of additional nuclear ATXN1 interactors in spinocerebellar ataxia type 1.Neuron2023
36909516NMRQNet: a deep learning approach for automatic identification and quantification of metabolites using Nuclear Magnetic Resonance (NMR) in human plasma samples.bioRxiv2023
36600199Single-cell multi-omics integration for unpaired data by a siamese network with graph-based contrastive loss.BMC Bioinformatics2023
36824948Unraveling Spatial Gene Associations with SEAGAL: a Python Package for Spatial Transcriptomics Data Analysis and Visualization.bioRxiv2023
35074918Disruption of MeCP2-TCF20 complex underlies distinct neurodevelopmental disorders.Proc Natl Acad Sci U S A2022
35442423Chemotherapy Coupled to Macrophage Inhibition Induces T-cell and B-cell Infiltration and Durable Regression in Triple-Negative Breast Cancer.Cancer Res2022
35370582A New Tool for Rapid Assessment of Acute Exercise-Induced Fatigue.Front Hum Neurosci2022
35499073Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1.J Clin Invest2022
35747619Genome Sequencing in the Parkinson Disease Clinic.Neurol Genet2022
36376296Region-specific denoising identifies spatial co-expression patterns and intra-tissue heterogeneity in spatially resolved transcriptomics data.Nat Commun2022
34146472Benchmarked approaches for reconstruction of in vitro cell lineages and in silico models of C. elegans and M. musculus developmental trees.Cell Syst2021
33878299The bone microenvironment increases phenotypic plasticity of ER<sup>+</sup> breast cancer cells.Dev Cell2021
33596411SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females.Am J Hum Genet2021
33871358Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.Elife2021
33845875A benchmark for RNA-seq deconvolution analysis under dynamic testing environments.Genome Biol2021
33709453Dual targeting of brain region-specific kinases potentiates neurological rescue in Spinocerebellar ataxia type 1.EMBO J2021
33841101Glial Cell-Based Vascular Mechanisms and Transplantation Therapies in Brain Vessel and Neurodegenerative Diseases.Front Cell Neurosci2021
33554954Modulation of ATXN1 S776 phosphorylation reveals the importance of allele-specific targeting in SCA1.JCI Insight2021
33658357Antisense oligonucleotide therapy in a humanized mouse model of <i>MECP2</i> duplication syndrome.Sci Transl Med2021
34183121A computational pipeline to infer alternative poly-adenylation from 3' sequencing data.Methods Enzymol2021
34183117Application and design considerations for 3'-end sequencing using click-chemistry.Methods Enzymol2021
33987465Genome-Wide Association Study Meta-Analysis for Parkinson Disease Motor Subtypes.Neurol Genet2021
30610205An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function.Mol Psychiatry2020
31971667Genome sequencing analysis of a family with a child displaying severe abdominal distention and recurrent hypoglycemia.Mol Genet Genomic Med2020
31999386BAZ2B haploinsufficiency as a cause of developmental delay, intellectual disability, and autism spectrum disorder.Hum Mutat2020
31917687Type I interferon response drives neuroinflammation and synapse loss in Alzheimer disease.J Clin Invest2020
33380334Stress detection using deep neural networks.BMC Med Inform Decis Mak2020
32993812Integrated analysis of the aging brain transcriptome and proteome in tauopathy.Mol Neurodegener2020
32763910miR760 regulates ATXN1 levels via interaction with its 5' untranslated region.Genes Dev2020
32668255Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.Cell Rep2020
32554779Coexpression enrichment analysis at the single-cell level reveals convergent defects in neural progenitor cells and their cell-type transitions in neurodevelopmental disorders.Genome Res2020
32386292GDASC: a GPU parallel-based web server for detecting hidden batch factors.Bioinformatics2020
32463457PolyA-miner: accurate assessment of differential alternative poly-adenylation from 3'Seq data using vector projections and non-negative matrix factorization.Nucleic Acids Res2020
32348450PRIME: a probabilistic imputation method to reduce dropout effects in single-cell RNA sequencing.Bioinformatics2020
32319885Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation.Elife2020
32425815Modulation of Stem Cells as Therapeutics for Severe Mental Disorders and Cognitive Impairments.Front Psychiatry2020
32159514Losing Dnmt3a dependent methylation in inhibitory neurons impairs neural function by a mechanism impacting Rett syndrome.Elife2020
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Collaborators

Baylor College of Medicine
Co-authored papers 43
Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital
Co-authored papers 12
Baylor College of Medicine
Co-authored papers 10
Baylor College of Medicine
Co-authored papers 8
Baylor College of Medicine
Co-authored papers 8
Rush University Medical Center
Co-authored papers 4
Columbia University Medical Center
Co-authored papers 4
Baylor College of Medicine, TX Jan and Dan Duncan Neurological Research Institute
Co-authored papers 4
Baylor College of Medicine
Co-authored papers 4
Baylor College of Medicine
Co-authored papers 4
Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine
Co-authored papers 3
Baylor College of Medicine
Co-authored papers 3
Co-authored papers 3
University of Washington
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
University of Pennsylvania
Co-authored papers 2
Center for Precision Health, The University of Texas Health Science Center at Houston
Co-authored papers 2
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
Fred Hutchinson Cancer Research Center
Co-authored papers 2
University of Michigan ann arbor
Co-authored papers 2
Children's Hospital Oakland Research Institute
Co-authored papers 2
Mayo Clinic College of Medicine and Science
Co-authored papers 2
Emory University School of Medicine
Co-authored papers 2
Baylor College of Medicine
Co-authored papers 2
Columbia University Irving Medical Center
Co-authored papers 2
Co-authored papers 2
Seattle Children's Hospital.
Co-authored papers 1
Institute of Computer Science, Warsaw University of Technology
Co-authored papers 1