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Author Details

Carole Mathis
Johns Hopkins Bayview Medical Center
1994
57
30
Dexter Pratt (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37719154Nicotine-mediated effects in neuronal and mouse models of synucleinopathy.Front Neurosci2023
35273209Causal biological network models for reactive astrogliosis: a systems approach to neuroinflammation.Sci Rep2022
35516526Toxicological Assessment of Flavor Ingredients in E-Vapor Products.Front Toxicol2022
34089800Effects of plant alkaloids on mitochondrial bioenergetic parameters.Food Chem Toxicol2021
33014713A meta-analysis of microRNAs expressed in human aerodigestive epithelial cultures and their role as potential biomarkers of exposure response to nicotine-containing products.Toxicol Rep2020
31197632Mitochondria as a possible target for nicotine action.J Bioenerg Biomembr2019
31886136Systems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells.Toxicol Rep2019
27775961Gastroparesis: Quality of Life and Health Care Utilization.J Clin Gastroenterol2018
29501877Comparative biological impacts of an aerosol from carbon-heated tobacco and smoke from cigarettes on human respiratory epithelial cultures: A systems toxicology assessment.Food Chem Toxicol2018
273886763-D nasal cultures: Systems toxicological assessment of a candidate modified-risk tobacco product.ALTEX2017
30090554Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach.Toxicol Res (Camb)2017
30090531Systems toxicology meta-analysis of <i>in vitro</i> assessment studies: biological impact of a candidate modified-risk tobacco product aerosol compared with cigarette smoke on human organotypic cultures of the aerodigestive tract.Toxicol Res (Camb)2017
28025120Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.Food Chem Toxicol2017
27865774A systems toxicology approach for comparative assessment: Biological impact of an aerosol from a candidate modified-risk tobacco product and cigarette smoke on human organotypic bronchial epithelial cultures.Toxicol In Vitro2017
27404394Systems Toxicology Assessment of the Biological Impact of a Candidate Modified Risk Tobacco Product on Human Organotypic Oral Epithelial Cultures.Chem Res Toxicol2016
26651182In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette.Chem Res Toxicol2016
27117495A framework for in vitro systems toxicology assessment of e-liquids.Toxicol Mech Methods2016
27256455Assessment of in vitro COPD models for tobacco regulatory science: Workshop proceedings, conclusions and paths forward for in vitro model use.Altern Lab Anim2016
25236459Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge.Bioinformatics2015
26277032Biological impact of cigarette smoke compared to an aerosol produced from a prototypic modified risk tobacco product on normal human bronchial epithelial cells.Toxicol In Vitro2015
26085348Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts.Toxicol Sci2015
25788831A systems biology approach reveals the dose- and time-dependent effect of primary human airway epithelium tissue culture after exposure to cigarette smoke in vitro.Bioinform Biol Insights2015
25741927Impact assessment of repeated exposure of organotypic 3D bronchial and nasal tissue culture models to whole cigarette smoke.J Vis Exp2015
24428674Systems biology approach for evaluating the biological impact of environmental toxicants in vitro.Chem Res Toxicol2014
25977767The species translation challenge-a systems biology perspective on human and rat bronchial epithelial cells.Sci Data2014
25297719The response of human nasal and bronchial organotypic tissue cultures to repeated whole cigarette smoke exposure.Int J Toxicol2014
24965703A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability.J Transl Med2014
25046638In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures.Toxicol Mech Methods2014
23355383Human bronchial epithelial cells exposed in vitro to cigarette smoke at the air-liquid interface resemble bronchial epithelium from human smokers.Am J Physiol Lung Cell Mol Physiol2013
24224167Systems approaches evaluating the perturbation of xenobiotic metabolism in response to cigarette smoke exposure in nasal and bronchial tissues.Biomed Res Int2013
23843693A modular cell-type focused inflammatory process network model for non-diseased pulmonary tissue.Bioinform Biol Insights2013
23926424Systematic verification of upstream regulators of a computable cellular proliferation network model on non-diseased lung cells using a dedicated dataset.Bioinform Biol Insights2013
23515068Construction of a computable network model for DNA damage, autophagy, cell death, and senescence.Bioinform Biol Insights2013
22651900Assessment of network perturbation amplitudes by applying high-throughput data to causal biological networks.BMC Syst Biol2012
21722388Construction of a computable cell proliferation network focused on non-diseased lung cells.BMC Syst Biol2011
22011616A computable cellular stress network model for non-diseased pulmonary and cardiovascular tissue.BMC Syst Biol2011
20093372Nogo-a regulates neural precursor migration in the embryonic mouse cortex.Cereb Cortex2010
18270832The effects of nebulized albuterol on esophageal function in asthmatic patients.Dig Dis Sci2008
16185313The effects of tegaserod, a 5-HT receptor agonist, on gastric emptying in a murine model of diabetes mellitus.Neurogastroenterol Motil2005
14694200Motor training compensates for cerebellar dysfunctions caused by oligodendrocyte ablation.Proc Natl Acad Sci U S A2004
15451898The treatment of diabetic gastroparesis with botulinum toxin injection of the pylorus.Diabetes Care2004
12925596Oligodendrocyte ablation impairs cerebellum development.Development2003
12061906Serotonin type-4 receptors modulate the sensitivity of intramural mechanoreceptive afferents of the cat rectum.Neurogastroenterol Motil2002
12391292Control of lactotrop proliferation by dopamine: essential role of signaling through D2 receptors and ERKs.Proc Natl Acad Sci U S A2002
12061911Influences of pelvic floor structures and sacral innervation on the response to distension of the cat rectum.Neurogastroenterol Motil2002
11731467Essential role of oligodendrocytes in the formation and maintenance of central nervous system nodal regions.Development2001
11027231A transgenic mouse model for inducible and reversible dysmyelination.J Neurosci2000
9614671Changes in pyloric resistance induced by erythromycin.Neurogastroenterol Motil1998
9458776Erythromycin gastrokinetic activity is partially vagally mediated.Am J Physiol1998
9486282Load-sensitive rat gastric vagal afferents encode volume but not gastric nutrients.Am J Physiol1998
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Collaborators

Philip Morris International Research Laboratories Pte. Ltd
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Vectura Fertin Pharma
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Universitat Basel
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University of California berkeley
Co-authored papers 5
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Co-authored papers 4
Philip Morris Research Laboratories GmbH
Co-authored papers 4
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Co-authored papers 3
IBM T.J. Watson Research Center
Co-authored papers 2
ProtATonce Ltd, National Technical University of Athens
Co-authored papers 2
FOG Pharmaceuticals Inc.
Co-authored papers 2
T.J. Watson Research Center
Co-authored papers 2
Co-authored papers 2
IBM T.J. Watson Research Center
Co-authored papers 2
Harvard Medical School
Co-authored papers 2
F. Hoffmann-La Roche Ltd
Co-authored papers 2
Torrey Mesa Research Institute/Syngenta Research and Technology
Co-authored papers 2
Co-authored papers 1
University of Michigan ann arbor
Co-authored papers 1
UC San Diego
Co-authored papers 1
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National Institute On Aging
Co-authored papers 1
University of Sassari
Co-authored papers 1