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Author Details

Alka Saxena
Biomedical Research Centre at Guy's Hospital
2000
43
28
PMIDPaper TitleJournal TitlePublished Year
32345968Engineered niches support the development of human dendritic cells in humanized mice.Nat Commun2020
31786163Phase I/II open-label trial of intravenous allogeneic mesenchymal stromal cell therapy in adults with recessive dystrophic epidermolysis bullosa.J Am Acad Dermatol2020
33362848Profiling of H3K27Ac Reveals the Influence of Asthma on the Epigenome of the Airway Epithelium.Front Genet2020
32610077Transcriptional and Functional Analysis of CD1c<sup>+</sup> Human Dendritic Cells Identifies a CD163<sup>+</sup> Subset Priming CD8<sup>+</sup>CD103<sup>+</sup> T Cells.Immunity2020
32689904Impact of Local Alloimmunity and Recipient Cells in Transplant Arteriosclerosis.Circ Res2020
32339978Genomic analysis in short- and long-term patients with malignant pleura mesothelioma treated with palliative chemotherapy.Eur J Cancer2020
30462217Dynamic transcriptomic analysis reveals suppression of PGC1α/ERRα drives perturbed myogenesis in facioscapulohumeral muscular dystrophy.Hum Mol Genet2019
31340667Single-Cell RNA-Sequencing and Metabolomics Analyses Reveal the Contribution of Perivascular Adipose Tissue Stem Cells to Vascular Remodeling.Arterioscler Thromb Vasc Biol2019
31619420Protocol for establishing a child and adolescent twin register for mental health research and capacity building in Sri Lanka and other low and middle-income countries in South Asia.BMJ Open2019
30850646Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02.Nat Commun2019
29870686Time Series Integrative Analysis of RNA Sequencing and MicroRNA Expression Data Reveals Key Biologic Wound Healing Pathways in Keloid-Prone Individuals.J Invest Dermatol2018
29851415Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes.J Clin Invest2018
28850106FANTOM5 CAGE profiles of human and mouse samples.Sci Data2017
29229843Machine learning shows association between genetic variability in <i>PPARG</i> and cerebral connectivity in preterm infants.Proc Natl Acad Sci U S A2017
28874660Integrative genomics of microglia implicates DLG4 (PSD95) in the white matter development of preterm infants.Nat Commun2017
26646931Association of MicroRNAs and YRNAs With Platelet Function.Circ Res2016
25678556Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.Science2015
26673794Remodeling of retrotransposon elements during epigenetic induction of adult visual cortical plasticity by HDAC inhibitors.Epigenetics Chromatin2015
26175406Chromerid genomes reveal the evolutionary path from photosynthetic algae to obligate intracellular parasites.Elife2015
24670764A promoter-level mammalian expression atlas.Nature2014
25539566CAGE-defined promoter regions of the genes implicated in Rett Syndrome.BMC Genomics2014
24993078Brain-specific noncoding RNAs are likely to originate in repeats and may play a role in up-regulating genes in cis.Int J Biochem Cell Biol2014
24777452Deep transcriptome profiling of mammalian stem cells supports a regulatory role for retrotransposons in pluripotency maintenance.Nat Genet2014
22668417Trehalose-enhanced isolation of neuronal sub-types from adult mouse brain.Biotechniques2012
23259945NMDA receptor regulation prevents regression of visual cortical function in the absence of Mecp2.Neuron2012
22976001piRNAs warrant investigation in Rett Syndrome: an omics perspective.Dis Markers2012
22722852Site-specific DICER and DROSHA RNA products control the DNA-damage response.Nature2012
22780904Mycobacterium tuberculosis WhiB4 regulates oxidative stress response to modulate survival and dissemination in vivo.Mol Microbiol2012
21197667Whole transcriptome analysis: what are we still missing?Wiley Interdiscip Rev Syst Biol Med2011
22056986Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila.Nature2011
21915889Long non-coding RNA modifies chromatin: epigenetic silencing by long non-coding RNAs.Bioessays2011
19481014Cells of epithelial lineage are present in blood, engraft the bronchial epithelium, and are increased in human lung transplantation.J Heart Lung Transplant2009
18434250Identification of genes of Mycobacterium tuberculosis upregulated during anaerobic persistence by fluorescence and kanamycin resistance selection.Tuberculosis (Edinb)2008
18820302MECP2 genomic structure and function: insights from ENCODE.Nucleic Acids Res2008
17204342Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiation.Mol Biochem Parasitol2007
17275824Characterization of the RNA polymerase II and III complexes in Leishmania major.Int J Parasitol2007
16155192Lost in translation: translational interference from a recurrent mutation in exon 1 of MECP2.J Med Genet2006
17058561Cancer chemotherapy and its side effect management.Nurs J India2006
12798511Evaluation of differential gene expression in Leishmania major Friedlin procyclics and metacyclics using DNA microarray analysis.Mol Biochem Parasitol2003
12011073Centromere proteins Cenpa, Cenpb, and Bub3 interact with poly(ADP-ribose) polymerase-1 protein and are poly(ADP-ribosyl)ated.J Biol Chem2002
12217960Poly(ADP-ribose) polymerase 2 localizes to mammalian active centromeres and interacts with PARP-1, Cenpa, Cenpb and Bub3, but not Cenpc.Hum Mol Genet2002
11770120The Leishmania genome project: new insights into gene organization and function.Med Microbiol Immunol2001
10607829Poly(ADP-ribose) polymerase at active centromeres and neocentromeres at metaphase.Hum Mol Genet2000
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Collaborators

Piero Carninci
RIKEN Center for Integrative Medical Sciences
Co-authored papers 13
Michela Fagiolini
Boston Children's Hospital, Harvard Medical School
Co-authored papers 7
Robin Andersson
University of Copenhagen
Co-authored papers 5
Albin Sandelin
University of Copenhagen
Co-authored papers 5
Alistair R R Forrest
RIKEN Center for Integrative Medical Sciences
Co-authored papers 5
Peter Heutink
German Center for Neurodegenerative Diseases (DZNE).
Co-authored papers 4
Thomas J Ha
University of British Columbia and BC Children's Hospital
Co-authored papers 4
Valerio Orlando
King Abdullah University of Science and Technology (KAUST)
Co-authored papers 4
Erik Arner
RIKEN Center for Integrative Medical Sciences (IMS)
Co-authored papers 4
Dave S B Hoon
Saint John's Cancer Institute at Saint John's Health Center
Co-authored papers 4
Harukazu Suzuki
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Morana Vitezic
University of Copenhagen
Co-authored papers 4
Nicolas Bertin
University Bordeaux, CNRS
Co-authored papers 4
Timo Lassmann
Telethon Kids Institute, University of Western Australia
Co-authored papers 4
Hideya Kawaji
RIKEN Center for Integrative Medical Sciences
Co-authored papers 4
Andreas Lennartsson
Karolinska Institute
Co-authored papers 4
Peter J Myler
University of Guelph
Co-authored papers 4
Dan Goldowitz
University of British Columbia
Co-authored papers 4
Peter Zhang
Child and Family Research Institute, University of British Columbia
Co-authored papers 4
Haruhiko Koseki
RIKEN Research Center for Allergy and Immunology
Co-authored papers 4
Carsten O Daub
International Institute of Molecular and Cell Biology in Warsaw
Co-authored papers 3
Alessandro Bonetti
RIKEN Center for Integrative Medical Sciences
Co-authored papers 3
Michael Detmar
Institute of Pharmaceutical Sciences, ETH Zurich
Co-authored papers 3
Naoto Kondo
Nagoya City University Graduate School of Medical Sciences
Co-authored papers 3
Yosuke Mizuno
Yokohama National University
Co-authored papers 3
Reto Guler
International Centre for Genetic Engineering and Biotechnology
Co-authored papers 3
Ernst J Wolvetang
Australian Institute for Bioengineering and Nanotechnology, University of Queensland
Co-authored papers 3
Suzana Savvi
South African Medical Research Council (SAMRC), University of Cape Town
Co-authored papers 3
Soichi Ogishima
Tohoku University Graduate School of Medicine
Co-authored papers 3
Christine L Mummery
Leiden University Medical Center
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Release 1.2