Author details

Full Name

Pradeep D Uchil

Affiliation

ORCID

Career Start Year

1998

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37292970	Immunogenicity and pre-clinical efficacy of an OMV-based SARS-CoV-2 vaccine.	Res Sq	2023
37993716	HIV-1 Env trimers asymmetrically engage CD4 receptors in membranes.	Nature	2023
37896949	Immunogenicity and Pre-Clinical Efficacy of an OMV-Based SARS-CoV-2 Vaccine.	Vaccines (Basel)	2023
37474505	Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry.		2023
36514310	Molecular basis for antiviral activity of two pediatric neutralizing antibodies targeting SARS-CoV-2 Spike RBD.	iScience	2023
37398307	Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice.		2023
37438530	PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection.	Nature	2023
37243110	Vaccinia Virus Strain MVA Expressing a Prefusion-Stabilized SARS-CoV-2 Spike Glycoprotein Induces Robust Protection and Prevents Brain Infection in Mouse and Hamster Models.	Vaccines (Basel)	2023
35123652	A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection.	Cell Reports	2022
35677392	VE607 stabilizes SARS-CoV-2 Spike in the "RBD-up" conformation and inhibits viral entry.	iScience	2022
35857504	Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities.	Science advances	2022
35233551	Fc effector cross-reactivity: A hidden arsenal against SARS-CoV-2's evasive maneuvering.	Cell Reports Medicine	2022
34971573	Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern.	Cell Rep	2022
34373853	Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern.	bioRxiv	2021
34133950	A single dose of the SARS-CoV-2 vaccine BNT162b2 elicits Fc-mediated antibody effector functions and TÂ cell responses.		2021
33758857	A single BNT162b2 mRNA dose elicits antibodies with Fc-mediated effector functions and boost pre-existing humoral and T cell responses.		2021
34453881	Live imaging of SARS-CoV-2 infection in mice reveals that neutralizing antibodies require Fc function for optimal efficacy.	Immunity	2021
34845451	Engineered ACE2-Fc counters murine lethal SARS-CoV-2 infection through direct neutralization and Fc-effector activities.		2021
33242391	Real-Time Conformational Dynamics of SARS-CoV-2 Spikes on Virus Particles.		2020
32935100	Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles.		2020
30824617	DNA Transfection Mediated by Cationic Lipid Reagents.	Cold Spring Harbor Protocols	2019
31575800	Transfection of Mammalian Cells with Calcium Phosphate-DNA Coprecipitates.	Cold Spring Harbor Protocols	2019
31575795	Calcium Phosphate-Mediated Transfection of Adherent Cells or Cells Growing in Suspension: Variations on the Basic Method.	Cold Spring Harbor Protocols	2019
31575794	Calcium Phosphate-Mediated Transfection of Cells with High-Molecular-Weight Genomic DNA.	Cold Spring Harbor Protocols	2019
31575793	Calcium Phosphate-Mediated Transfection of Eukaryotic Cells with Plasmid DNAs.	Cold Spring Harbor Protocols	2019
31805155	Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice.	PLoS Pathogens	2019
30595553	A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus.		2019
31285274	Introducing Genes into Cultured Mammalian Cells.	Cold Spring Harbor Protocols	2019
31283440	In Vivo Imaging-Driven Approaches to Study Virus Dissemination and Pathogenesis.	Annual Review of Virology	2019
31434732	Murine Leukemia Virus Exploits Innate Sensing by Toll-Like Receptor 7 in B-1 Cells To Establish Infection and Locally Spread in Mice.	J Virol	2019
31262965	Electroporation.	Cold Spring Harbor Protocols	2019
31262956	DNA Transfection by Electroporation.	Cold Spring Harbor Protocols	2019
30824627	Lipofection.	Cold Spring Harbor Protocols	2019
30824618	Histochemical Staining of Cell Monolayers for Î²-Galactosidase.	Cold Spring Harbor Protocols	2019
29606496	Small Interfering RNA-Mediated Control of Virus Replication in the CNS Is Therapeutic and Enables Natural Immunity to West Nile Virus.		2018
30510131	Optical Transfection.	Cold Spring Harbor Protocols	2018
29967279	DEAE-Dextran Transfection.	Cold Spring Harbor Protocols	2018
29967275	Transfection Mediated by DEAE-Dextran.	Cold Spring Harbor Protocols	2018
29858338	Analysis of Cell Viability by the MTT Assay.	Cold Spring Harbor Protocols	2018
29858337	Analysis of Cell Viability by the Lactate Dehydrogenase Assay.	Cold Spring Harbor Protocols	2018
29858336	Analysis of Cell Viability by the alamarBlue Assay.	Cold Spring Harbor Protocols	2018
30181228	Selective Agents for Stable Transfection.	Cold Spring Harbor Protocols	2018
28974657	Assay for Î²-Galactosidase in Extracts of Mammalian Cells.	Cold Spring Harbor Protocols	2017
28974659	Î²-Galactosidase.	Cold Spring Harbor Protocols	2017
26468522	TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling.	Journal of Virology	2016
26429886	Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.	Science	2015
25544044	Attachment of cell-binding ligands to arginine-rich cell-penetrating peptides enables cytosolic translocation of complexed siRNA.		2015
25766144	HIV cell-to-cell transmission: effects on pathogenesis and antiretroviral therapy.	Trends in Microbiology	2015
25015296	TRIM15 is a focal adhesion protein that regulates focal adhesion disassembly.	J Cell Sci	2014
24586175	Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response.	PLoS Pathog	2014