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Author Details

Christopher M Hovens
Royal Melbourne Hospital, The University of Melbourne
1989
119
37
PMIDPaper TitleJournal TitlePublished Year
36610996A polygenic two-hit hypothesis for prostate cancer.J Natl Cancer Inst2023
37890967Phase II randomised placebo-controlled trial of sodium selenate as a disease-modifying treatment in chronic drug-resistant temporal lobe epilepsy: the SeLECT study protocol.BMJ Open2023
36230886Molecular Mechanisms Driving the Formation of Brain Metastases.Cancers (Basel)2022
35574563A phase 1b open-label study of sodium selenate as a disease-modifying treatment for possible behavioral variant frontotemporal dementia.Alzheimers Dement (N Y)2022
35688680Phase 2 Study of Neoadjuvant FGFR Inhibition and Androgen Deprivation Therapy Prior to Prostatectomy.Clin Genitourin Cancer2022
35659150Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study.Eur Urol2022
35811101Identification and isolation of slow-cycling glioma stem cells.Methods Cell Biol2022
36103484Perish and publish: Dynamics of biomedical publications by deceased authors.PLoS One2022
33389014Toward precision immunotherapy using multiplex immunohistochemistry and in silico methods to define the tumor immune microenvironment.Cancer Immunol Immunother2021
35474657Ductal adenocarcinoma of the prostate: A systematic review and meta-analysis of incidence, presentation, prognosis, and management.BJUI Compass2021
33678516Ductal variant prostate carcinoma is associated with a significantly shorter metastasis-free survival.Eur J Cancer2021
34916328Sodium selenate as a disease-modifying treatment for progressive supranuclear palsy: protocol for a phase 2, randomised, double-blind, placebo-controlled trial.BMJ Open2021
35008330Biomarkers of Response to Neoadjuvant Androgen Deprivation in Localised Prostate Cancer.Cancers (Basel)2021
34988458Sodium selenate as a disease-modifying treatment for mild-moderate Alzheimer's disease: an open-label extension study.BMJ Neurol Open2021
34322653Loss of <i>SNAI2</i> in Prostate Cancer Correlates With Clinical Response to Androgen Deprivation Therapy.JCO Precis Oncol2021
34294073Transcriptome sequencing and multi-plex imaging of prostate cancer microenvironment reveals a dominant role for monocytic cells in progression.BMC Cancer2021
34310033The modified International Society of Urological Pathology system improves concordance between biopsy and prostatectomy tumour grade.BJU Int2021
34108644MSH2-deficient prostate tumours have a distinct immune response and clinical outcome compared to MSH2-deficient colorectal or endometrial cancer.Prostate Cancer Prostatic Dis2021
33419682The Mutational Landscape of Metastatic Castration-sensitive Prostate Cancer: The Spectrum Theory Revisited.Eur Urol2021
32314873Prostate cancer cell-intrinsic interferon signaling regulates dormancy and metastatic outgrowth in bone.EMBO Rep2020
32807235Detection of ctDNA in plasma of patients with clinically localised prostate cancer is associated with rapid disease progression.Genome Med2020
32392735The Impact of Whole Genome Data on Therapeutic Decision-Making in Metastatic Prostate Cancer: A Retrospective Analysis.Cancers (Basel)2020
30382379Developments in oligometastatic hormone-sensitive prostate cancer.World J Urol2019
30215171Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease.Neurotherapeutics2019
30248237Late biochemical recurrence after radical prostatectomy is associated with a slower rate of progression.BJU Int2019
30772200Prostatic nerve subtypes independently predict biochemical recurrence in prostate cancer.J Clin Neurosci2019
30959474Androgen deprivation therapy promotes an obesity-like microenvironment in periprostatic fat.Endocr Connect2019
30642810What Is Oligometastatic Prostate Cancer?Eur Urol Focus2019
30562483Cell quiescence correlates with enhanced glioblastoma cell invasion and cytotoxic resistance.Exp Cell Res2019
29592867Periprostatic fat tissue transcriptome reveals a signature diagnostic for high-risk prostate cancer.Endocr Relat Cancer2018
30596026Preparation of fluorescent in situ hybridisation probes without the need for optimisation of fragmentation.MethodsX2018
29661963Obesity suppresses tumor attributable PSA, affecting risk categorization.Endocr Relat Cancer2018
27431748Routinely reported 'equivocal' lymphovascular invasion in prostatectomy specimens is associated with adverse outcomes.BJU Int2017
29050365Mitochondrial genome variation and prostate cancer: a review of the mutational landscape and application to clinical management.Oncotarget2017
28710841Accelerated kindling epileptogenesis in Tg4510 tau transgenic mice, but not in tau knockout mice.Epilepsia2017
27896520Early perfusion MRI predicts survival outcome in patients with recurrent glioblastoma treated with bevacizumab and carboplatin.J Neurooncol2017
27864419How Subclonal Modeling Is Changing the Metastatic Paradigm.Clin Cancer Res2017
27824348Androgen synthesis in prostate cancer: do all roads lead to Rome?Nat Rev Urol2017
27554242Disrupting the Status Quo in Prostate Cancer Diagnosis.Eur Urol2017
26812572A urinary microRNA signature can predict the presence of bladder urothelial carcinoma in patients undergoing surveillance.Br J Cancer2016
28881726Modulation of paracrine signaling by CD9 positive small extracellular vesicles mediates cellular growth of androgen deprived prostate cancer.Oncotarget2016
27653089Comparing nodal versus bony metastatic spread using tumour phylogenies.Sci Rep2016
27120785Reduction in expression of the benign AR transcriptome is a hallmark of localised prostate cancer progression.Oncotarget2016
27169997Molecular Pathways: Targeting DNA Repair Pathway Defects Enriched in Metastasis.Clin Cancer Res2016
27447428A Phase IIa Randomized Control Trial of VEL015 (Sodium Selenate) in Mild-Moderate Alzheimer's Disease.J Alzheimers Dis2016
27289302Sodium selenate retards epileptogenesis in acquired epilepsy models reversing changes in protein phosphatase 2A and hyperphosphorylated tau.Brain2016
27163189Sodium selenate, a protein phosphatase 2A activator, mitigates hyperphosphorylated tau and improves repeated mild traumatic brain injury outcomes.Neuropharmacology2016
25444993Repair mechanisms help glioblastoma resist treatment.J Clin Neurosci2015
26308396Preoperative biomarkers of tumour vascularity are elevated in patients with glioblastoma multiforme.J Clin Neurosci2015
25882061Target Acquired: Progress and Promise of Targeted Therapeutics in the Treatment of Prostate Cancer.Curr Cancer Drug Targets2015
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Collaborators

Royal Melbourne Hospital, The University of Melbourne
Co-authored papers 77
Royal Melbourne Hospital
Co-authored papers 49
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 12
Monash University
Co-authored papers 11
Australian Prostate Cancer Research Centre Epworth
Co-authored papers 8
University of British Columbia
Co-authored papers 5
University of Melbourne
Co-authored papers 4
Clinical Sciences Building, The University of Melbourne, The Royal Melbourne Hospital
Co-authored papers 4
University of California los angeles
Co-authored papers 4
University of Oxford, John Radcliffe Hospital
Co-authored papers 3
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 3
University of Oxford
Co-authored papers 3
Co-authored papers 3
Manchester Cancer Research Centre, University of Manchester
Co-authored papers 3
Peter MacCallum Cancer Centre, University of Melbourne
Co-authored papers 3
University of Melbourne, The University of Melbourne
Co-authored papers 3
University of Copenhagen
Co-authored papers 2
King's College London
Co-authored papers 2
NIHR Oxford Biomedical Research Centre
Co-authored papers 2
University of Oxford
Co-authored papers 2
UCSF Medical Center-Mount Zion
Co-authored papers 2
Weill Medical College of Cornell University
Co-authored papers 2
University of California san francisco
Co-authored papers 2
Ghent University, GZA Ziekenhuizen
Co-authored papers 2
Cambridge University Hospitals National Health Service Foundation Trust
Co-authored papers 2
University of California los angeles
Co-authored papers 2
University of Cambridge
Co-authored papers 2
University of Toronto
Co-authored papers 2
The Francis Crick Institute
Co-authored papers 2
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 2