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Author Details

William R Pearson
University of Virginia
1974
92
43
PMIDPaper TitleJournal TitlePublished Year
36482890Comparison of detection methods and genome quality when quantifying nuclear mitochondrial insertions in vertebrate genomes.Front Genet2022
29870542Bioinformatics core competencies for undergraduate life sciences education.PLoS One2018
27923999Query-seeded iterative sequence similarity searching improves selectivity 5-20-fold.Nucleic Acids Res2017
28902397Using SQL Databases for Sequence Similarity Searching and Analysis.Curr Protoc Bioinformatics2017
27010337Finding Protein and Nucleotide Similarities with FASTA.Curr Protoc Bioinformatics2016
27175996Applying, Evaluating and Refining Bioinformatics Core Competencies (An Update from the Curriculum Task Force of ISCB's Education Committee).PLoS Comput Biol2016
25976240Most partial domains in proteins are alignment and annotation artifacts.Genome Biol2015
26334923Protein Function Prediction: Problems and Pitfalls.Curr Protoc Bioinformatics2015
24170396BLAST and FASTA similarity searching for multiple sequence alignment.Methods Mol Biol2014
24319146The Catalytic Site Atlas 2.0: cataloging catalytic sites and residues identified in enzymes.Nucleic Acids Res2014
23749753An introduction to sequence similarity ("homology") searching.Curr Protoc Bioinformatics2013
24509512Selecting the Right Similarity-Scoring Matrix.Curr Protoc Bioinformatics2013
23995390Adjusting scoring matrices to correct overextended alignments.Bioinformatics2013
22058127MACiE: exploring the diversity of biochemical reactions.Nucleic Acids Res2012
22539666PSI-Search: iterative HOE-reduced profile SSEARCH searching.Bioinformatics2012
20064877Homologous over-extension: a challenge for iterative similarity searches.Nucleic Acids Res2010
20693322RefProtDom: a protein database with improved domain boundaries and homology relationships.Bioinformatics2010
20307279Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments.BMC Bioinformatics2010
19948773Globally, unrelated protein sequences appear random.Bioinformatics2010
16891377Exploring the relationship between sequence similarity and accurate phylogenetic trees.Mol Biol Evol2006
15919194The limits of protein sequence comparison?Curr Opin Struct Biol2005
16399387Phylogenies of glutathione transferase families.Methods Enzymol2005
16399376Nomenclature for mammalian soluble glutathione transferases.Methods Enzymol2005
14978311Sensitivity and selectivity in protein structure comparison.Protein Sci2004
18428739Using relational databases for improved sequence similarity searching and large-scale genomic analyses.Curr Protoc Bioinformatics2004
18428723Finding protein and nucleotide similarities with FASTA.Curr Protoc Bioinformatics2004
15510150The genome of Cryptosporidium hominis.Nature2004
14751975Visualization of near-optimal sequence alignments.Bioinformatics2004
12486119Identification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesign.J Biol Chem2003
12824437CRP: Cleavage of Radiolabeled Phosphoproteins.Nucleic Acids Res2003
12038961Identification and characterization of GSTT3, a third murine Theta class glutathione transferase.Biochem J2002
12427470Entamoeba histolytica: sequence conservation of the Gal/GalNAc lectin from clinical isolates.Exp Parasitol2002
12424122Empirical determination of effective gap penalties for sequence comparison.Bioinformatics2002
12096132Getting more from less: algorithms for rapid protein identification with multiple short peptide sequences.Mol Cell Proteomics2002
12096113A strategy for the rapid identification of phosphorylation sites in the phosphoproteome.Mol Cell Proteomics2002
11590093Training for bioinformatics and computational biology.Bioinformatics2001
10547837Flexible sequence similarity searching with the FASTA3 program package.Methods Mol Biol2000
9854036Gene structure, expression and chromosomal localization of murine theta class glutathione transferase mGSTT1-1.Biochem J1999
10368958Generalized neighbor-joining: more reliable phylogenetic tree reconstruction.Mol Biol Evol1999
10452901Evolution of protein sequences and structures.J Mol Biol1999
9882431Distinctive structure of the human GSTM3 gene-inverted orientation relative to the mu class glutathione transferase gene cluster.Arch Biochem Biophys1999
10207159Panning for genes--A visual strategy for identifying novel gene orthologs and paralogs.Genome Res1999
9733729Rapid identification of protein phosphatase 1-binding proteins by mixed peptide sequencing and data base searching. Characterization of a novel holoenzymic form of protein phosphatase 1.J Biol Chem1998
9452477Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion.J Biol Chem1998
9514730Empirical statistical estimates for sequence similarity searches.J Mol Biol1998
9403055Comparison of DNA sequences with protein sequences.Genomics1997
9283747Identifying distantly related protein sequences.Comput Appl Biosci1997
9278064Aligning a DNA sequence with a protein sequence.J Comput Biol1997
8743688Effective protein sequence comparison.Methods Enzymol1996
7584448A new approach to primer selection in polymerase chain reaction experiments.Proc Int Conf Intell Syst Mol Biol1995
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Collaborators

HemoShear Therapeutics LLC
Co-authored papers 8
Co-authored papers 4
California Institute of Technology
Co-authored papers 3
J. Craig Venter Institute
Co-authored papers 2
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Co-authored papers 2
University of California
Co-authored papers 2
Clinical Epidemiology Research Center (CERC), VA Connecticut Healthcare System
Co-authored papers 1
Co-authored papers 1
University of Oxford, John Radcliffe Hospital
Co-authored papers 1
University of Cape Town
Co-authored papers 1
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Virginia Commonwealth University.
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 1
Co-authored papers 1
Lawrence Berkeley National Laboratory
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
Indiana University
Co-authored papers 1
Co-authored papers 1
Carnegie Mellon University
Co-authored papers 1
College of Nursing, University of Iowa Hospitals and Clinics
Co-authored papers 1
Virginia Commonwealth University.
Co-authored papers 1
Huck Institutes of Life Sciences, The Pennsylvania State University, University Park
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Co-authored papers 1
University of Virginia
Co-authored papers 1
Institute of Biology, Freie Universitat Berlin
Co-authored papers 1
Illumina Cambridge Ltd
Co-authored papers 1
New York University Grossman School of Medicine
Co-authored papers 1