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Author Details

Martin J Lercher
Institute for Computer Science, Heinrich Heine University
1994
112
42
PMIDPaper TitleJournal TitlePublished Year
36423222Viridiplantae-specific GLXI and GLXII isoforms co-evolved and detoxify glucosone in planta.Plant Physiol2023
37795991Proteome efficiency of metabolic pathways in <i>Escherichia coli</i> increases along the nutrient flow.mSystems2023
37943930Thinking about science<b>I've Been Thinking</b> <i>Daniel C. Dennett</i> Norton, 2023. 464 pp.Science2023
37188731A general model to predict small molecule substrates of enzymes based on machine and deep learning.Nat Commun2023
37279246Mathematical properties of optimal fluxes in cellular reaction networks at balanced growth.PLoS Comput Biol2023
36973558Make science disruptive again.Nat Biotechnol2023
37307285Optimal density of bacterial cells.PLoS Comput Biol2023
34980206Improvisational science.Genome Biol2022
36008862What puzzle are you in?Genome Biol2022
34354112Modeling photosynthetic resource allocation connects physiology with evolutionary environments.Sci Rep2021
33568179The data-hypothesis conversation.Genome Biol2021
34762478Iterations of evolution<b>A (Very) Short History of Life on Earth</b> <i>Henry Gee</i> St. Martin's Press, 2021. 288 pp.Science2021
34699521On the optimality of the enzyme-substrate relationship in bacteria.PLoS Biol2021
34665809Deep learning allows genome-scale prediction of Michaelis constants from structural features.PLoS Biol2021
34843465An optimal growth law for RNA composition and its partial implementation through ribosomal and tRNA gene locations in bacterial genomes.PLoS Genet2021
34516872Interdependence of a mechanosensitive anion channel and glutamate receptors in distal wound signaling.Sci Adv2021
33955487Distinct identities of leaf phloem cells revealed by single cell transcriptomics.Plant Cell2021
33975619Novel predictions arise from contradictions.Genome Biol2021
32169112Renaissance minds in 21st century science.Genome Biol2020
31748914Network reduction methods for genome-scale metabolic models.Cell Mol Life Sci2020
33067428The protein translation machinery is expressed for maximal efficiency in Escherichia coli.Nat Commun2020
32883349A hypothesis is a liability.Genome Biol2020
32552854The two languages of science.Genome Biol2020
32144263An analytical theory of balanced cellular growth.Nat Commun2020
30563853Each of 3,323 metabolic innovations in the evolution of <i>E. coli</i> arose through the horizontal transfer of a single DNA segment.Proc Natl Acad Sci U S A2019
31856863What is the question?Genome Biol2019
31681190Prokaryotic Genome Expansion Is Facilitated by Phages and Plasmids but Impaired by CRISPR.Front Microbiol2019
31413270Flux balance analysis with or without molecular crowding fails to predict two thirds of experimentally observed epistasis in yeast.Sci Rep2019
31462323Night science.Genome Biol2019
31235877Molecular adaptations of NADP-malic enzyme for its function in C<sub>4</sub> photosynthesis in grasses.Nat Plants2019
31114888Evolview v3: a webserver for visualization, annotation, and management of phylogenetic trees.Nucleic Acids Res2019
29177508MVP: a microbe-phage interaction database.Nucleic Acids Res2018
29873761Corrigendum: Freeze-quenched maize mesophyll and bundle sheath separation uncovers bias in previous tissue-specific RNA-Seq data.J Exp Bot2018
30531987Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models.Nat Commun2018
30467356Alleles of a gene differ in pleiotropy, often mediated through currency metabolite production, in E. coli and yeast metabolic simulations.Sci Rep2018
29718170BlockFeST: Bayesian calculation of region-specific FST to detect local adaptation.Bioinformatics2018
28067311Supra-operonic clusters of functionally related genes (SOCs) are a source of horizontal gene co-transfers.Sci Rep2017
28247236The ancestors of diatoms evolved a unique mitochondrial dehydrogenase to oxidize photorespiratory glycolate.Photosynth Res2017
28419089Erroneous energy-generating cycles in published genome scale metabolic networks: Identification and removal.PLoS Comput Biol2017
28600545HOTAIR rs7958904 polymorphism is associated with increased cervical cancer risk in a Chinese population.Sci Rep2017
28874819Selection for energy efficiency drives strand-biased gene distribution in prokaryotes.Sci Rep2017
28043950Freeze-quenched maize mesophyll and bundle sheath separation uncovers bias in previous tissue-specific RNA-Seq data.J Exp Bot2017
27660481Combining genetic and evolutionary engineering to establish C4 metabolism in C3 plants.J Exp Bot2017
27098217Energy efficiency trade-offs drive nucleotide usage in transcribed regions.Nat Commun2016
27482704Improved Metabolic Models for E. coli and Mycoplasma genitalium from GlobalFit, an Algorithm That Simultaneously Matches Growth and Non-Growth Data Sets.PLoS Comput Biol2016
27197754Adaptive evolution of complex innovations through stepwise metabolic niche expansion.Nat Commun2016
27131786Evolview v2: an online visualization and management tool for customized and annotated phylogenetic trees.Nucleic Acids Res2016
26936472Forty years of The Selfish Gene are not enough.Genome Biol2016
25273104WhopGenome: high-speed access to whole-genome variation and sequence data in R.Bioinformatics2015
26690249Horizontally transferred genes cluster spatially and metabolically.Biol Direct2015
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Collaborators

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University of Cologne
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Max Planck Institute for Evolutionary Biology
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Oregon Health & Science University, University of California Berkeley
Co-authored papers 2
European Bioinformatics Institute (EMBL-EBI)
Co-authored papers 2
Beijing Institute of Genomics, Chinese Academy of Sciences
Co-authored papers 1
Institute of Molecular Systems Biology, ETH Zurich
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Monoceros Biosystems LLC
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University of Toronto
Co-authored papers 1
Max-Planck-Institute for Neurological Research
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Institute of Genetics and Developmental Biology, Chinese Academy of Sciences
Co-authored papers 1
University of Turin and INFN
Co-authored papers 1
Duke University
Co-authored papers 1
University of Rochester
Co-authored papers 1
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University of Toronto
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Max Planck Institute of Immunobiology and Epigenetics
Co-authored papers 1
The Genome Center at Washington University, Washington University School of Medicine
Co-authored papers 1
University of Minnesota - Twin Cities
Co-authored papers 1
Baylor College of Medicine
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Baylor College of Medicine
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Institut fur Mathematik und Informatik, Universitat Greifswald
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