Author details

Full Name

Joanna M M Howson

Affiliation

ORCID

Career Start Year

2002

Papers

121

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36787970	Prognostic modelling of clinical outcomes after first-time acute coronary syndrome in New Zealand.	Heart	2023
37122688	Hepatocyte mARC1 promotes fatty liver disease.		2023
35264566	Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.	Nat Commun	2022
35388009	Publisher Correction: Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.	Nat Commun	2022
36357675	Rare and common genetic determinants of metabolic individuality and their effects on human health.	Nat Med	2022
35948913	Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups.	BMC Med	2022
35690124	Kidney omics in hypertension: from statistical associations to biological mechanisms and clinical applications.	Kidney Int	2022
36253349	Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke.	Nat Commun	2022
34426706	Mitochondrial DNA variants modulate N-formylmethionine, proteostasis and risk of late-onset human diseases.	Nat Med	2021
33536417	A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits.	Nat Commun	2021
34002094	An atlas of mitochondrial DNA genotype-phenotype associations in the UK Biobank.	Nat Genet	2021
33727701	Publisher Correction: Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2021
34184541	Genetic Evidence for Repurposing of GLP1R (Glucagon-Like Peptide-1 Receptor) Agonists to Prevent Heart Failure.	J Am Heart Assoc	2021
34505161	Leveraging human genetic data to investigate the cardiometabolic effects of glucose-dependent insulinotropic polypeptide signalling.	Diabetologia	2021
30617275	Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.	Mol Psychiatry	2020
32080192	Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.	Nat Commun	2020
31953392	A robust and efficient method for Mendelian randomization with hundreds of genetic variants.	Nat Commun	2020
32358547	Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants.	Nature Communications	2020
33230300	Discovery of rare variants associated with blood pressure regulation through meta-analysis of 1.3 million individuals.	Nat Genet	2020
32888494	The Polygenic and Monogenic Basis of Blood Traits and Diseases.	Cell	2020
32888493	Trans-ethnic and Ancestry-Specific Blood-Cell Genetics in 746,667 Individuals from 5 Global Populations.	Cell	2020
30837465	Assessing the causal association of glycine with risk of cardio-metabolic diseases.	Nat Commun	2019
31862893	Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.	Nat Commun	2019
31160809	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2019
29273807	Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
30355092	Serum 25-Hydroxyvitamin D Concentrations and Ischemic Stroke and Its Subtypes.	Stroke	2018
29926099	Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis.	JAMA Cardiol	2018
30429575	Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018
30224653	Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits.	Nat Genet	2018
29531354	Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.	Nat Genet	2018
29549330	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29549329	Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.	Nat Genet	2018
29459775	Formalising recall by genotype as an efficient approach to detailed phenotyping and causal inference.	Nat Commun	2018
29632382	Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.	Nat Genet	2018
29360107	Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2018
28146470	Rare and low-frequency coding variants alter human adult height.	Nature	2017
28869590	Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease.	Nat Genet	2017
28951623	Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Nat Genet	2017
28594416	A comparison of Cox and logistic regression for use in genome-wide association studies of cohort and case-cohort design.	Eur J Hum Genet	2017
28714975	Association analyses based on false discovery rate implicate new loci for coronary artery disease.	Nat Genet	2017
28663568	Rare Variant Analysis of Human and Rodent Obesity Genes in Individuals with Severe Childhood Obesity.	Sci Rep	2017
28530674	Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms.	Nat Genet	2017
29030403	New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475â¿¿000 Individuals.	Circ Cardiovasc Genet	2017
29083408	Exome-wide association study of plasma lipids in >300,000 individuals.	Nat Genet	2017
29257133	Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2017
27940953	Genetic invalidation of Lp-PLA<sub>2</sub> as a therapeutic target: Large-scale study of five functional Lp-PLA<sub>2</sub>-lowering alleles.	Eur J Prev Cardiol	2017
28135244	Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.	Nat Genet	2017
28209224	Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated WithÂ Coronary ArteryÂ Disease.	J Am Coll Cardiol	2017
27618447	Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.	Nat Genet	2016
27252175	A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.	Sci Transl Med	2016