Author details

Full Name

Clare Pridans

Affiliation

ORCID

Career Start Year

2006

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37191268	Synthesis and Development of Highly Selective Pyrrolo[2,3-]pyrimidine CSF1R Inhibitors Targeting the Autoinhibited Form.		2023
37922341	CSF1R-dependent macrophages in the salivary gland are essential for epithelial regeneration after radiation-induced injury.		2023
37957324	Microglia promote anti-tumour immunity and suppress breast cancer brain metastasis.		2023
36517604	Microglia regulate central nervous system myelin growth and integrity.		2023
35333324	A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling.	Development	2022
35705056	Absence of microglia promotes diverse pathologies and early lethality in Alzheimer's disease mice.	Cell Rep	2022
35568024	CD11c identifies microbiota and EGR2-dependent MHCII serous cavity macrophages with sexually dimorphic fate in mice.	European Journal of Immunology	2022
35437746	Cell origin and niche availability dictate the capacity of peritoneal macrophages to colonize the cavity and omentum.	Immunology	2022
35624205	Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation.	Nat Immunol	2022
36327895	Microglia states and nomenclature: A field at its crossroads.	Neuron	2022
35854097	Author Correction: Hypoxia shapes the immune landscape in lung injury and promotes the persistence of inflammation.	Nat Immunol	2022
35852018	Microglia deficiency accelerates prion disease but does not enhance prion accumulation in the brain.	Glia	2022
33450391	Analysis of homozygous and heterozygous Csf1r knockout in the rat as a model for understanding microglial function in brain development and the impacts of human CSF1R mutations.	Neurobiol Dis	2021
33965905	The Mononuclear Phagocyte System of the Rat.	J Immunol	2021
33633725	Transcriptomic Analysis of Rat Macrophages.	Front Immunol	2021
33951750	Sialic acid-binding immunoglobulin-like lectin (Sigelac)-15 is a rapidly internalised cell-surface antigen expressed by acute myeloid leukaemia cells.	Br J Haematol	2021
31330095	Phenotypic impacts of CSF1R deficiencies in humans and model organisms.	J Leukoc Biol	2020
33139489	A Transgenic Line That Reports CSF1R Protein Expression Provides a Definitive Marker for the Mouse Mononuclear Phagocyte System.	J Immunol	2020
32793601	Species-Specificity of Transcriptional Regulation and the Response to Lipopolysaccharide in Mammalian Macrophages.	Front Cell Dev Biol	2020
33323375	CNS macrophages differentially rely on an intronic <i>Csf1r</i> enhancer for their development.	Development	2020
31397014	Analysis of the impact of CSF-1 administration in adult rats using a novel Csf1r-mApple reporter gene.	J Leukoc Biol	2020
31324781	Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations.	Nat Commun	2019
30579704	The Mononuclear Phagocyte System: The Relationship between Monocytes and Macrophages.	Trends Immunol	2019
30758286	Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development.	eLife	2019
31028122	Correction: Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the <i>Csf1r</i> Locus.	J Immunol	2019
29593242	The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche.	Nat Commun	2018
30076102	The Transcription Factor ZEB2 Is Required to Maintain the Tissue-Specific Identities of Macrophages.	Immunity	2018
30594166	A chicken bioreactor for efficient production of functional cytokines.	BMC Biotechnol	2018
30249809	Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the <i>Csf1r</i> Locus.	J Immunol	2018
30327653	ADGRE1 (EMR1, F4/80) Is a Rapidly-Evolving Gene Expressed in Mammalian Monocyte-Macrophages.	Front Immunol	2018
30467554	Species-Specific Transcriptional Regulation of Genes Involved in Nitric Oxide Production and Arginine Metabolism in Macrophages.	Immunohorizons	2018
29351395	Macrophage colony-stimulating factor increases hepatic macrophage content, liver growth, and lipid accumulation in neonatal rats.	Am J Physiol Gastrointest Liver Physiol	2018
29440354	<i>Csf1r</i>-mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System.	J Immunol	2018
29215000	The evolution of the macrophage-specific enhancer (Fms intronic regulatory element) within the CSF1R locus of vertebrates.	Sci Rep	2017
28915238	A high resolution atlas of gene expression in the domestic sheep (Ovis aries).	PLoS Genet	2017
28760770	Transcriptional mechanisms that control expression of the macrophage colony-stimulating factor receptor locus.	Clin Sci (Lond)	2017
27521343	A Csf1r-EGFP Transgene Provides a Novel Marker for Monocyte Subsets in Sheep.	J Immunol	2016
25137049	The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration.	PLoS One	2014
26015955	Lentiviral vectors containing mouse Csf1r control elements direct macrophage-restricted expression in multiple species of birds and mammals.	Mol Ther Methods Clin Dev	2014
24652541	Pleiotropic effects of extended blockade of CSF1R signaling in adult mice.	J Leukoc Biol	2014
24962162	Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor.	Mol Ther	2014
23708655	HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.	Oncogene	2013
24145216	CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function.	Sci Rep	2013
23383005	The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus.	PLoS One	2013
23260168	Cloning and expression of feline colony stimulating factor receptor (CSF-1R) and analysis of the species specificity of stimulation by colony stimulating factor-1 (CSF-1) and interleukin-34 (IL-34).	Cytokine	2013
23327922	Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.	Blood	2013
22006020	The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic stem cells.	Mol Cell Biol	2011
20676125	A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients.	Oncogene	2010
18209069	Identification of Pax5 target genes in early B cell differentiation.	J Immunol	2008
17998914	The regulation of the B-cell gene expression programme by Pax5.	Immunology and Cell Biology	2008