Author details

Full Name

Rebecca J Leary

Affiliation

ORCID

Career Start Year

2005

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36989374	Clonal hematopoiesis detection in patients with cancer using cell-free DNA sequencing.		2023
36702949	Combined PD-1, BRAF and MEK inhibition in BRAF<sup>V600E</sup> colorectal cancer: a phase 2 trial.	Nat Med	2023
32722845	Immune Signature Variation in Twins With Clinically Different Recurrent Respiratory Papillomatosis.	Laryngoscope	2021
34045463	Cell-free DNA captures tumor heterogeneity and driver alterations in rapid autopsies with pre-treated metastatic cancer.	Nature Communications	2021
32870995	Generic Protocols for the Analytical Validation of Next-Generation Sequencing-Based ctDNA Assays: A Joint Consensus Recommendation of the BloodPAC's Analytical Variables Working Group.	Clin Chem	2020
31747139	A community-based lung cancer rapid tissue donation protocol provides high-quality drug-resistant specimens for proteogenomic analyses.	Cancer Med	2020
30643118	Author Correction: Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.	Nat Commun	2019
29376144	Tracking the Evolution of Resistance to ALK Tyrosine Kinase Inhibitors through Longitudinal Analysis of Circulating Tumor DNA.	JCO Precis Oncol	2018
30327465	Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.	Nat Commun	2018
30275569	Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia.	Nat Med	2018
28187516	Collaborating to Compete: Blood Profiling Atlas in Cancer (BloodPAC) Consortium.	Clin Pharmacol Ther	2017
27159400	Association of MTOR Mutations With Developmental Brain Disorders, Including Megalencephaly, Focal Cortical Dysplasia, and Pigmentary Mosaicism.	JAMA Neurol	2016
26154128	Clinical implications of genomic alterations in the tumour and circulation of pancreatic cancer patients.	Nat Commun	2015
25849130	Studying clonal dynamics in response to cancer therapy using high-complexity barcoding.	Nature Medicine	2015
26479923	High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.	Nat Med	2015
24553385	Detection of circulating tumor DNA in early- and late-stage human malignancies.	Sci Transl Med	2014
23202128	Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.	Nat Genet	2013
23912395	Cancer detection using whole-genome sequencing of cell free DNA.	Oncotarget	2013
23264394	Exomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.	J Clin Endocrinol Metab	2013
23197571	Detection of chromosomal alterations in the circulation of cancer patients with whole-genome sequencing.	Sci Transl Med	2012
21163964	The genetic landscape of the childhood cancer medulloblastoma.	Science	2011
20371490	Development of personalized tumor biomarkers using massively parallel sequencing.	Sci Transl Med	2010
20981102	Distant metastasis occurs late during the genetic evolution of pancreatic cancer.	Nature	2010
19426505	Identification of microbial DNA in human cancer.	BMC Med Genomics	2009
19584151	SMAD4 gene mutations are associated with poor prognosis in pancreatic cancer.	Clin Cancer Res	2009
19351817	Genetic mutations associated with cigarette smoking in pancreatic cancer.	Cancer Res	2009
18852474	Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers.	Proc Natl Acad Sci U S A	2008
18772396	An integrated genomic analysis of human glioblastoma multiforme.	Science	2008
18772397	Core signaling pathways in human pancreatic cancers revealed by global genomic analyses.	Science	2008
17932254	The genomic landscapes of human breast and colorectal cancers.	Science	2007
17703209	Digital karyotyping.		2007
16505370	The colorectal microRNAome.	Proc Natl Acad Sci U S A	2006
16959974	The consensus coding sequences of human breast and colorectal cancers.	Science	2006
15860664	The Shwachman-Diamond SBDS protein localizes to the nucleolus.	Blood	2005