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Author Details

Christopher Ian Spencer
Gladstone Institute of Cardiovascular Disease
1988
31
17
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
26971820CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs.Cell Stem Cell2016
27984724Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis.Cell2016
27127239Conversion of human fibroblasts into functional cardiomyocytes by small molecules.Science2016
26942852Expandable Cardiovascular Progenitor Cells Reprogrammed from Fibroblasts.Cell Stem Cell2016
27095412Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses.Sci Rep2016
26932671KMT2D regulates specific programs in heart development via histone H3 lysine 4 di-methylation.Development2016
25333967Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Cultured over Different Spatial Scales.Tissue Eng Part C Methods2015
24561253Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4.Cell Rep2014
25254341Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia.Stem Cell Reports2014
24319660Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state.Stem Cell Reports2013
22574656Ion channel pharmacology under flow: automation via well-plate microfluidics.Assay Drug Dev Technol2012
22522929In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes.Nature2012
18996139Actions of ATX-II and other gating-modifiers on Na(+) currents in HEK-293 cells expressing WT and DeltaKPQ hNa(V) 1.5 Na(+) channels.Toxicon2009
17603033Differential pharmacology of the cardiac anionic background current I(AB).Eur J Pharmacol2007
15980056Mechanisms underlying the effects of the pyrethroid tefluthrin on action potential duration in isolated rat ventricular myocytes.J Pharmacol Exp Ther2005
15138823Differential effects of extracellular cesium on early afterdepolarizations in ventricular myocytes and arrhythmogenesis in isolated hearts of rats and guinea pigs.Pflugers Arch2004
12933341Effects of Na+/Ca2+ exchange induced by SR Ca2+ release on action potentials and afterdepolarizations in guinea pig ventricular myocytes.Am J Physiol Heart Circ Physiol2003
11890694Tefluthrin modulates a novel anionic background conductance (I(AB)) in guinea-pig ventricular myocytes.Biochem Biophys Res Commun2002
11504804Actions of pyrethroid insecticides on sodium currents, action potentials, and contractile rhythm in isolated mammalian ventricular myocytes and perfused hearts.J Pharmacol Exp Ther2001
10694227A novel anionic conductance affects action potential duration in isolated rat ventricular myocytes.Br J Pharmacol2000
10860770Loading of calcium and strontium into the sarcoplasmic reticulum in rat ventricular muscle.J Mol Cell Cardiol2000
11084386Cardiac chloride channels: physiology, pharmacology and approaches for identifying novel modulators of activity.Drug Discov Today2000
11150408Signature currents: a patch-clamp method for determining the selectivity of ion-channel blockers in isolated cardiac myocytes.J Cardiovasc Pharmacol Ther2000
9401965Calcium-induced release of strontium ions from the sarcoplasmic reticulum of rat cardiac ventricular myocytes.J Physiol1997
7491285A method for recording intracellular [Ca2+] transients in cardiac myocytes using calcium green-2.Pflugers Arch1995
8568669Control of sarcoplasmic reticulum calcium release during calcium loading in isolated rat ventricular myocytes.J Physiol1995
7510921Influences of stimulation frequency and temperature on interval-force relationships in guinea-pig papillary muscles.Acta Physiol Scand1994
8003309Effects of gadolinium on length-dependent force in guinea-pig papillary muscle.Exp Physiol1994
8389120Effects of nifedipine and low [Ca2+] on mechanical restitution during hypothermia in guinea pig papillary muscles.Basic Res Cardiol1993
1451152Mechanical restitution during alternans in guinea pig papillary muscles.Cardiovasc Res1992
2970206The elementary steps of the actomyosin ATPase in muscle fibres studied with caged-ATP.Adv Exp Med Biol1988
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Collaborators

Deepak Srivastava
Gladstone Institutes San Francisco
Co-authored papers 7
Bruce R Conklin
Gladstone Institutes
Co-authored papers 4
Yu Huang
Gladstone Institutes San Francisco
Co-authored papers 4
Luke M Judge
Gladstone Institutes
Co-authored papers 3
Tao Xu
Co-authored papers 3
Nathaniel Huebsch
Washington University in St. Louis
Co-authored papers 3
Benoit G Bruneau
Gladstone Institutes of Cardiovascular Disease, Gladstone Institutes
Co-authored papers 3
Mohammad A Mandegar
Gladstone Institute of Cardiovascular Disease
Co-authored papers 3
Po-Lin So
Gladstone Institutes
Co-authored papers 3
Jennie Yoo
University of California San Francisco Department of Psychiatry
Co-authored papers 2
Lei Liu
Center for Developmental Biology, Anhui Agricultural University
Co-authored papers 2
Nicole R Stone
Gladstone Institutes
Co-authored papers 2
Annie Truong
Gladstone Institutes
Co-authored papers 2
Amy Foley
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
David E Gordon
Emory University
Co-authored papers 1
Luke A Gilbert
Arc Institute
Co-authored papers 1
Haiyuan Yu
Weill Institute for Cell and Molecular Biology, Cornell University
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Kristin Holmes
Gladstone Institute of Cardiovascular Disease
Co-authored papers 1
Michael P Olvera
University of California san francisco
Co-authored papers 1
Yuichiro Miyaoka
Tokyo Metropolitan Institute of Medical Science, Japan Gladstone Institutes
Co-authored papers 1
Rohith Srivas
Amgen Inc.
Co-authored papers 1
Kai Ge
Co-authored papers 1
Edward C Shin
University of California san francisco
Co-authored papers 1
S??ren P Sheikh
Odense University Hospital
Co-authored papers 1
Tejal A Desai
University of California San Francisco
Co-authored papers 1
Jacqueline E Villalta
University of California san francisco
Co-authored papers 1
Tilde V Eskildsen
Odense University Hospital, University of Southern Denmark
Co-authored papers 1
Yen-Sin Ang
Gladstone Institutes
Co-authored papers 1
Alexandre J S Ribeiro
Center for Drug Evaluation and Research
Co-authored papers 1
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