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Author Details

Jennifer A Doudna
Innovative Genomics Institute, University of California berkeley
1987
359
117
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37889041CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes.Nucleic Acids Res2024
36656942CRISPR technology: A decade of genome editing is only the beginning.Science2023
37917583Targeting the non-coding genome and temozolomide signature enables CRISPR-mediated glioma oncolysis.Cell Rep2023
37863261Assembly of SARS-CoV-2 ribonucleosomes by truncated N<sup>⿿</sup> variant of the nucleocapsid protein.J Biol Chem2023
38014180Engineering self-deliverable ribonucleoproteins for genome editing in the brain.bioRxiv2023
38014175Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR-Cas9 RNP.bioRxiv2023
37794590Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells.Cell2023
37790334A phage nucleus-associated RNA-binding protein is required for jumbo phage infection.bioRxiv2023
37738970SARS-CoV-2 variants evolve convergent strategies to remodel the host response.Cell2023
37781618Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection.bioRxiv2023
37609353Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes.bioRxiv2023
37973815Infant microbiome cultivation and metagenomic analysis reveal Bifidobacterium 2'-fucosyllactose utilization can be facilitated by coexisting species.Nat Commun2023
37869789Previous exposure to Spike-providing parental strains confers neutralizing immunity to XBB lineage and other SARS-CoV-2 recombinants in the context of vaccination.Emerg Microbes Infect2023
36993359Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells.bioRxiv2023
37316664Genome expansion by a CRISPR trimmer-integrase.Nature2023
37085489Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6.Nat Commun2023
37403358Genome editing in the mouse brain with minimally immunogenic Cas9 RNPs.Mol Ther2023
36652483Genome editing in plants using the compact editor CasΦ.Proc Natl Acad Sci U S A2023
36690762Precise transcript targeting by CRISPR-Csm complexes.Nat Biotechnol2023
36798416Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA.1 variant through NSP6.bioRxiv2023
36797405To TnpB or not TnpB? Cas12 is the answer.Nat Chem Biol2023
35104875CRISPR-Cas9-mediated nuclear transport and genomic integration of nanostructured genes in human primary cells.Nucleic Acids Res2022
35584773Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination.Nature2022
35436289Crystal structure of an RNA/DNA strand exchange junction.PLoS One2022
35858386Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles.Proc Natl Acad Sci U S A2022
35365639A functional map of HIV-host interactions in primary human T cells.Nat Commun2022
35422516CRISPR-Cas9 bends and twists DNA to read its sequence.Nat Struct Mol Biol2022
35659325A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression.Mol Cell2022
35562427Structural biology of CRISPR-Cas immunity and genome editing enzymes.Nat Rev Microbiol2022
36459645Decorating chromatin for enhanced genome editing using CRISPR-Cas9.Proc Natl Acad Sci U S A2022
36423580Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.Cell2022
36098733Treatment of Genetic Diseases With CRISPR Genome Editing.JAMA2022
36261517Borgs are giant genetic elements with potential to expand metabolic capacity.Nature2022
36316451Broad-spectrum CRISPR-Cas13a enables efficient phage genome editing.Nat Microbiol2022
36114166Conserved features of TERT promoter duplications reveal an activation mechanism that mimics hotspot mutations in cancer.Nat Commun2022
35219382Chimeric CRISPR-CasX enzymes and guide RNAs for improved genome editing activity.Mol Cell2022
34873292Species- and site-specific genome editing in complex bacterial communities.Nat Microbiol2022
32895548Massively parallel kinetic profiling of natural and engineered CRISPR nucleases.Nat Biotechnol2021
33828315The NIH Somatic Cell Genome Editing program.Nature2021
33545038Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.Cell2021
33758097Cancer-specific loss of <i>TERT</i> activation sensitizes glioblastoma to DNA damage.Proc Natl Acad Sci U S A2021
33693715A CRISPR-Cas9-integrase complex generates precise DNA fragments for genome integration.Nucleic Acids Res2021
33608277Quantification of Cas9 binding and cleavage across diverse guide sequences maps landscapes of target engagement.Sci Adv2021
33495623Genome-resolved metagenomics reveals site-specific diversity of episymbiotic CPR bacteria and DPANN archaea in groundwater ecosystems.Nat Microbiol2021
34382787Synthesis of Multi-Protein Complexes through Charge-Directed Sequential Activation of Tyrosine Residues.J Am Chem Soc2021
34381246DNA interference states of the hypercompact CRISPR-CasΦ effector.Nat Struct Mol Biol2021
34758033LuNER: Multiplexed SARS-CoV-2 detection in clinical swab and wastewater samples.PLoS One2021
34814094Optimizing COVID-19 control with asymptomatic surveillance testing in a university environment.Epidemics2021
34580310Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules.Nat Commun2021
34505008Kinetic analysis of Cas12a and Cas13a RNA-Guided nucleases for development of improved CRISPR-Based diagnostics.iScience2021
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Collaborators

Christopher S Fraser
College of Biological Sciences, University of California davis
Co-authored papers 10
Adam P Arkin
Lawrence Berkeley National Laboratory
Co-authored papers 7
Stephen N Floor
University of California san francisco
Co-authored papers 7
Alexander Marson
Gladstone-UCSF Institute of Genomic Immunology
Co-authored papers 6
Yun Bai
Carnegie Institution for Science
Co-authored papers 6
David F Savage
University of California berkeley
Co-authored papers 6
Jennifer R Hamilton
University of California berkeley
Co-authored papers 5
Mir M Khalid
Gladstone Institutes
Co-authored papers 5
Melanie Ott
Gladstone Institute of Virology
Co-authored papers 5
Erik J Sontheimer
Co-authored papers 5
Rodolphe Barrangou
Innovative Genomics Institute, University of California berkeley
Co-authored papers 5
David R Liu
Co-authored papers 5
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 5
Jacob E Corn
Co-authored papers 5
Gaurav Kumar
Gladstone Institutes
Co-authored papers 5
Audrone Lapinaite
Arizona State University
Co-authored papers 5
Albert J R Heck
Utrecht University
Co-authored papers 4
Lei S Qi
Stanford University
Co-authored papers 4
Jonathan S Weissman
Whitehead Institute for Biomedical Research
Co-authored papers 4
Tatsuya Yamamoto
Gladstone Institutes
Co-authored papers 4
Nikos C Kyrpides
Co-authored papers 4
Jennifer K Sabo
Innovative Genomics Institute, University of California berkeley
Co-authored papers 4
Chia-Lin Tsou
Gladstone Institutes
Co-authored papers 4
Taha Y Taha
Gladstone Institutes
Co-authored papers 4
Rahul K Suryawanshi
Gladstone Institutes
Co-authored papers 4
Wendell A Lim
University of California san francisco
Co-authored papers 4
Kathrin Schumann
Institute for Medical Microbiology, Technical University of Munich (TUM)
Co-authored papers 3
Joseph F Costello
University of California san francisco
Co-authored papers 3
Luke A Gilbert
Arc Institute
Co-authored papers 3
Carol V Robinson
University of Oxford
Co-authored papers 3
Release 1.2