Author details

Full Name

Todd VanArsdale

Affiliation

Oncology Research Unit, Inc.

ORCID

Career Start Year

1991

Papers

H Index

Expertise

CM4AI Collaborator

Trey Ideker (CM4AI)

PMID	Paper Title	Journal Title	Published Year
37267950	Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity.	Cell	2023
37169829	Multimodal perturbation analyses of cyclin-dependent kinases reveal a network of synthetic lethalities associated with cell-cycle regulation and transcriptional regulation.	Sci Rep	2023
34668577	Real-World Data of Palbociclib in Combination With Endocrine Therapy for the Treatment of Metastatic Breast Cancer in Men.	Clin Pharmacol Ther	2022
36070389	A two-step mechanism governing PARP1-DNA retention by PARP inhibitors.	Sci Adv	2022
35864202	PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor, Talazoparib.	Sci Rep	2022
35974168	Comparative biomarker analysis of PALOMA-2/3 trials for palbociclib.	NPJ Precis Oncol	2022
33361107	Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.	J Biol Chem	2021
34520734	Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor.	Cancer Cell	2021
32109375	CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma.	Cancer Cell	2020
33049208	CDK4/6 Inhibitors Impair Recovery from Cytotoxic Chemotherapy in Pancreatic Adenocarcinoma.	Cancer Cell	2020
30700828	Combining CDK4/6 inhibition with taxanes enhances anti-tumor efficacy by sustained impairment of pRB-E2F pathways in squamous cell lung cancer.	Oncogene	2019
31727874	Cisplatin exposure causes c-Myc-dependent resistance to CDK4/6 inhibition in HPV-negative head and neck squamous cell carcinoma.	Cell Death Dis	2019
29229993	Therapeutic relevance of the PP2A-B55 inhibitory kinase MASTL/Greatwall in breast cancer.	Cell Death Differ	2018
30012580	A versatile drug delivery system targeting senescent cells.	EMBO Mol Med	2018
27496135	Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance.	Mol Cancer Ther	2016
25387892	Combination of 4-1BB agonist and PD-1 antagonist promotes antitumor effector/memory CD8 T cells in a poorly immunogenic tumor model.	Cancer Immunol Res	2015
25889765	GLI2 inhibition abrogates human leukemia stem cell dormancy.	J Transl Med	2015
25991817	Efficacy of SERD/SERM Hybrid-CDK4/6 Inhibitor Combinations in Models of Endocrine Therapy-Resistant Breast Cancer.	Clin Cancer Res	2015
25941111	Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment.	Clin Cancer Res	2015
24563505	Pillars article: A lymphotoxin-B-specific receptor. Science. 1994. 264: 707-710.	J Immunol	2014
25389372	Resistance to dual blockade of the kinases PI3K and mTOR in KRAS-mutant colorectal cancer models results in combined sensitivity to inhibition of the receptor tyrosine kinase EGFR.	Sci Signal	2014
23403635	Development of a colon cancer GEMM-derived orthotopic transplant model for drug discovery and validation.	Clin Cancer Res	2013
24326223	Contrast agents for quantitative microCT of lung tumors in mice.	Comp Med	2013
23826249	Antitumor Efficacy of the Dual PI3K/mTOR Inhibitor PF-04691502 in a Human Xenograft Tumor Model Derived from Colorectal Cancer Stem Cells Harboring a PIK3CA Mutation.	PLoS One	2013
23820871	Combined gemcitabine and CHK1 inhibitor treatment induces apoptosis resistance in cancer stem cell-like cells enriched with tumor spheroids from a non-small cell lung cancer cell line.	Front Med	2013
20829331	PF-03732010: a fully human monoclonal antibody against P-cadherin with antitumor and antimetastatic activity.	Clin Cancer Res	2010
19169242	Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia.	Nature	2009
19729306	Structure-based design of novel human Pin1 inhibitors (I).	Bioorg Med Chem Lett	2009
10514511	TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction.	J Biol Chem	1999
9626059	TRAF-4 expression in epithelial progenitor cells. Analysis in normal adult, fetal, and tumor tissues.	Am J Pathol	1998
9545235	IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases.	EMBO J	1998
8995654	Hepatitis C virus core protein interacts with the cytoplasmic tail of lymphotoxin-beta receptor.	J Virol	1997
9122217	Lymphotoxin-beta receptor signaling complex: role of tumor necrosis factor receptor-associated factor 3 recruitment in cell death and activation of nuclear factor kappaB.	Proc Natl Acad Sci U S A	1997
9550380	Immunohistochemical analysis of in vivo patterns of TRAF-3 expression, a member of the TNF receptor-associated factor family.	J Immunol	1997
8825415	Apoptosis mediated by the TNF-related cytokine and receptor families.	J Cell Biochem	1996
7859281	The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family.	Cell	1995
7774281	The ligands and receptors of the lymphotoxin system.	Curr Top Microbiol Immunol	1995
8171323	A lymphotoxin-beta-specific receptor.	Science	1994
8288897	Production of lymphotoxin (LT alpha) and a soluble dimeric form of its receptor using the baculovirus expression system.	J Immunol Methods	1994
8089485	TNF receptor signal transduction. Ligand-dependent stimulation of a serine protein kinase activity associated with (CD120a) TNFR60.	J Immunol	1994
8258697	Specific induction of 80-kDa tumor necrosis factor receptor shedding in T lymphocytes involves the cytoplasmic domain and phosphorylation.	J Immunol	1993
1661312	Tumor necrosis factor (TNF) receptor expression in T lymphocytes. Differential regulation of the type I TNF receptor during activation of resting and effector T cells.	J Immunol	1991

1 - 42 of 42

Evangelos Pazarentzos

University of California san francisco

Career Start Year 2011

Number of shared co-authors 0

Jianying Zhang

City of Hope National Medical Center

Career Start Year 2009

Number of shared co-authors 0

Jaclyn LoPiccolo

Dana-Farber Cancer Institute

Career Start Year 2007

Number of shared co-authors 0

Shweta Joshi

Moores Cancer Center, University of California

Career Start Year 2007

Number of shared co-authors 3

Xiaohu Zhang

National Center for Advancing Translational Sciences

Career Start Year 2003

Number of shared co-authors 0

Elena Ivanova

Dana-Farber Cancer Institute

Career Start Year 2003

Number of shared co-authors 0

David J Liewehr

Center for Cancer Research

Career Start Year 1999

Number of shared co-authors 0

Yaqin Zhang

Jiangsu University Zhenjiang 212013

Career Start Year 1999

Number of shared co-authors 0

Chandra C Ghosh

The Wistar Institute

Career Start Year 1999

Number of shared co-authors 0

Ni Liu

Princess Margaret Cancer Centre, University Health Network, University of Toronto

Career Start Year 1997

Number of shared co-authors 2

Theresa M LaVallee

Parker Institute for Cancer Immunotherapy

Career Start Year 1996

Number of shared co-authors 0

Michael Peyton

Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center

Career Start Year 1994

Number of shared co-authors 1

Mark M Moasser

Helen Diller Family Comprehensive Cancer Center

Career Start Year 1994

Number of shared co-authors 1

Krister Wennerberg

University of Copenhagen

Career Start Year 1994

Number of shared co-authors 0

Jan Paul Medema

Oncode Institute

Career Start Year 1993

Number of shared co-authors 1

Aykut Uren

Georgetown University Medical Center

Career Start Year 1991

Number of shared co-authors 0

Ricky W Johnstone

The University of Melbourne

Career Start Year 1990

Number of shared co-authors 0

Wei Zhang

The University of Texas MD Anderson Cancer Center

Career Start Year 1988

Number of shared co-authors 2

Daniel S Peeper

Netherlands Cancer Institute

Career Start Year 1987

Number of shared co-authors 1

William C Hahn

Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute

Career Start Year 1987

Number of shared co-authors 1

Rakesh Kumar

Rutgers New Jersey Medical School

Career Start Year 1987

Number of shared co-authors 2

David J McConkey

Johns Hopkins School of Medicine

Career Start Year 1986

Number of shared co-authors 3

Daniel E Johnson

University of California San Francisco

Career Start Year 1985

Number of shared co-authors 2

John A Copland

Mayo Clinic Jacksonville

Career Start Year 1982

Number of shared co-authors 1

Stephen E Kurtz

Knight Cancer Institute, Oregon Health and Science University

Career Start Year 1979

Number of shared co-authors 0

Donald L Durden

Atrium Health-Levine Cancer Institute

Career Start Year 1979

Number of shared co-authors 3

Stanley Lipkowitz

Center for Cancer Research, National Cancer Institute

Career Start Year 1978

Number of shared co-authors 0

Scott H Kaufmann

Mayo Clinic

Career Start Year 1977

Number of shared co-authors 1

Gordon B Mills

Knight Cancer Institute, Oregon Health and Sciences University

Career Start Year 1976

Number of shared co-authors 6

Antonio Jimeno

University of Colorado School of Medicine

Career Start Year 1974

Number of shared co-authors 0

row(s) 1 - 30 of 30

Carl F Ware

Sanford Burnham Prebys Medical Discovery Institute

Co-authored papers 11

Zhou Zhu

Co-authored papers 5

Jadwiga Bienkowska

Pfizer Global Research and Development La Jolla

Co-authored papers 2

Stan Krajewski

Cellstan-Immunoquant Inc.

Co-authored papers 2

Carlos Caldas

Cancer Research UK Cambridge Institute, University of Cambridge

Co-authored papers 1

Alexander E Gorbalenya

Leiden University Medical Center

Co-authored papers 1

Wai K Chu

University of California San Diego

Co-authored papers 1

Joseph Rainaldi

University of California San Diego

Co-authored papers 1

Shunqiang Li

Co-authored papers 1

Dario Meluzzi

University of California San Diego

Co-authored papers 1

Thomas Paul

Co-authored papers 1

Matthew J Ellis

Co-authored papers 1

Lei Bao

Moores Cancer Center, university of california san diego Health System

Co-authored papers 1

Tina Primeau

Co-authored papers 1

Vinayagam Arunachalam

Co-authored papers 1

David A Rizzieri

Duke University Medical Center

Co-authored papers 1

Prashant Mali (CM4AI)

University of California San Diego

Co-authored papers 1

Massimo Cristofanilli

Weill Cornell School of Medicine

Co-authored papers 1

Jason F Kreisberg

University of California San Diego

Co-authored papers 1

Ramnik J Xavier

Broad Institute of MIT and Harvard

Co-authored papers 1

Marco A Marra

University of British Columbia

Co-authored papers 1

Kyle Ford

University of California San Diego

Co-authored papers 1

Jarek Kostrowicki

Co-authored papers 1

Karen Messer

Herbert Wertheim School of Public Health, University of California San Diego

Co-authored papers 1

John D McPherson

Ontario Institute for Cancer Research

Co-authored papers 1

Minya Pu

University of California

Co-authored papers 1

Michael A White

University of Georgia

Co-authored papers 1

Brenton Munson

University of California San Diego

Co-authored papers 1

Rebecca Panwala

University of California San Diego

Co-authored papers 1

Richard A Moore

Co-authored papers 1

1 - 30

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