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Author Details

Thomas B Acton
Center for Advanced Biotechnology and Medicine, The State University of New Jersey
1986
129
32
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37235475Protocol for production and purification of SARS-CoV-2 3CL<sup>pro</sup>.STAR Protoc2023
33984267Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture.Cell Rep2021
28066922X-ray crystal structure of the N-terminal region of Moloney murine leukemia virus integrase and its implications for viral DNA recognition.Proteins2017
28470618High-Throughput Production of Proteins in E. coli for Structural Studies.Methods Mol Biol2017
28900304The campaign for a National Strategy for Gypsy site provision and the role of Public Health activism in the 1960-1970s.J Public Health Policy2017
26760206Codon influence on protein expression in E. coli correlates with mRNA levels.Nature2016
26293815A community resource of experimental data for NMR / X-ray crystal structure pairs.Protein Sci2016
24722902Polypeptide backbone, C(β) and methyl group resonance assignments of the 24 kDa plectin repeat domain 6 from human protein plectin.Biomol NMR Assign2015
26071966The second round of Critical Assessment of Automated Structure Determination of Proteins by NMR: CASD-NMR-2013.J Biomol NMR2015
26165597The RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRAS.Structure2015
25388768A hybrid NMR/SAXS-based approach for discriminating oligomeric protein interfaces using Rosetta.Proteins2015
24203321DisMeta: a meta server for construct design and optimization.Methods Mol Biol2014
25010333Structural and functional characterization of DUF1471 domains of Salmonella proteins SrfN, YdgH/SssB, and YahO.PLoS One2014
24989974Solution NMR structures of immunoglobulin-like domains 7 and 12 from obscurin-like protein 1 contribute to the structural coverage of the Human Cancer Protein Interaction Network.J Struct Funct Genomics2014
24941917Solution NMR structures of homeodomains from human proteins ALX4, ZHX1, and CASP8AP2 contribute to the structural coverage of the Human Cancer Protein Interaction Network.J Struct Funct Genomics2014
24512202Structure and function of human DnaJ homologue subfamily a member 1 (DNAJA1) and its relationship to pancreatic cancer.Biochemistry2014
24456211Allosteric regulation and substrate activation in cytosolic nucleotidase II from Legionella pneumophila.FEBS J2014
23303792Structures of apo- and ssDNA-bound YdbC from Lactococcus lactis uncover the function of protein domain family DUF2128 and expand the single-stranded DNA-binding domain proteome.Nucleic Acids Res2013
24048810Solution NMR structure of CD1104B from pathogenic Clostridium difficile reveals a distinct α-helical architecture and provides first structural representative of protein domain family PF14203.J Struct Funct Genomics2013
24039739Structure determination and biochemical characterization of a putative HNH endonuclease from Geobacter metallireducens GS-15.PLoS One2013
24215428Structural and biochemical characterization of the bilin lyase CpcS from Thermosynechococcus elongatus.Biochemistry2013
23963952Solution NMR structures provide first structural coverage of the large protein domain family PF08369 and complementary structural coverage of dark operative protochlorophyllide oxidoreductase complexes.J Struct Funct Genomics2013
23978068A bidirectional system for the dynamic small molecule control of intracellular fusion proteins.ACS Chem Biol2013
23791943Crystal structures of malonyl-coenzyme A decarboxylase provide insights into its catalytic mechanism and disease-causing mutations.Structure2013
23542644Two Fe-S clusters catalyze sulfur insertion by radical-SAM methylthiotransferases.Nat Chem Biol2013
23160728Solution NMR structure of the helicase associated domain BVU_0683(627-691) from Bacteroides vulgatus provides first structural coverage for protein domain family PF03457 and indicates domain binding to DNA.J Struct Funct Genomics2013
21933118Human retinoblastoma binding protein 9, a serine hydrolase implicated in pancreatic cancers.Protein Pept Lett2012
23135467Principles for designing ideal protein structures.Nature2012
22733734Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples.Proc Natl Acad Sci U S A2012
22693626NMR structure of lipoprotein YxeF from Bacillus subtilis reveals a calycin fold and distant homology with the lipocalin Blc from Escherichia coli.PLoS One2012
22865330Solution NMR and X-ray crystal structures of Pseudomonas syringae Pspto_3016 from protein domain family PF04237 (DUF419) adopt a "double wing" DNA binding motif.J Struct Funct Genomics2012
22876860Structure of a specialized acyl carrier protein essential for lipid A biosynthesis with very long-chain fatty acids in open and closed conformations.Biochemistry2012
22843345Crystal structure of a catalytically active GG(D/E)EF diguanylate cyclase domain from Marinobacter aquaeolei with bound c-di-GMP product.J Struct Funct Genomics2012
22843344Three structural representatives of the PF06855 protein domain family from Staphyloccocus aureus and Bacillus subtilis have SAM domain-like folds and different functions.J Struct Funct Genomics2012
22497251Solution NMR structure, backbone dynamics, and heme-binding properties of a novel cytochrome c maturation protein CcmE from Desulfovibrio vulgaris.Biochemistry2012
22592539Solution NMR structure of Alr2454 from Nostoc sp. PCC 7120, the first structural representative of Pfam domain family PF11267.J Struct Funct Genomics2012
22223187Solution NMR structures reveal unique homodimer formation by a winged helix-turn-helix motif and provide first structures for protein domain family PF10771.J Struct Funct Genomics2012
22422653Solution NMR structure of the ribosomal protein RP-L35Ae from Pyrococcus furiosus.Proteins2012
22070628'I think we're all guinea pigs really': a qualitative study of medication and borderline personality disorder.J Psychiatr Ment Health Nurs2012
22113821Solution NMR structure of Asl3597 from Nostoc sp. PCC7120, the first structure from protein domain family PF12095, reveals a novel fold.Proteins2012
22198206Solution NMR structures reveal a distinct architecture and provide first structures for protein domain family PF04536.J Struct Funct Genomics2012
22116783Solution NMR structure of BT_0084, a conjugative transposon lipoprotein from Bacteroides thetaiotamicron.Proteins2012
20979070Solution NMR structure of the plasmid-encoded fimbriae regulatory protein PefI from Salmonella enterica serovar Typhimurium.Proteins2011
22587847Large-scale experimental studies show unexpected amino acid effects on protein expression and solubility in vivo in E. coli.Microb Inform Exp2011
22102225A large conformational change in the putative ATP pyrophosphatase PF0828 induced by ATP binding.Acta Crystallogr Sect F Struct Biol Cryst Commun2011
21828055Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation.J Biol Chem2011
21785987Solution NMR structure of MED25(391-543) comprising the activator-interacting domain (ACID) of human mediator subunit 25.J Struct Funct Genomics2011
21905121Solution NMR structure of VF0530 from Vibrio fischeri reveals a nucleic acid-binding function.Proteins2011
21904870Solution NMR structure of Dsy0195 homodimer from Desulfitobacterium hafniense: first structure representative of the YabP domain family of proteins involved in spore coat assembly.J Struct Funct Genomics2011
21371586Preparation of protein samples for NMR structure, function, and small-molecule screening studies.Methods Enzymol2011
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Collaborators

Rensselaer Polytechnic Institute
Co-authored papers 120
School of Public Health, Capital Medical University
Co-authored papers 101
Columbia University
Co-authored papers 24
Miami University
Co-authored papers 23
Technical University of Munich (TUM)
Co-authored papers 23
Robert Wood Johnson Medical School, The State University of New Jersey
Co-authored papers 22
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Co-authored papers 22
Columbia University
Co-authored papers 20
Pacific Northwest National Laboratory
Co-authored papers 16
Center for Advanced Biotechnology and Medicine, The State University of New Jersey
Co-authored papers 13
Co-authored papers 12
Columbia University Irving Medical Center
Co-authored papers 10
Columbia University
Co-authored papers 10
The University of Texas MD Anderson Cancer Center
Co-authored papers 9
The Ohio State University
Co-authored papers 9
Guizhou Medical University
Co-authored papers 7
Robert Wood Johnson Medical School, Rutgers University
Co-authored papers 6
Bio-X Institutes, Shanghai Jiao Tong University
Co-authored papers 6
Co-authored papers 6
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Co-authored papers 6
University of Toronto
Co-authored papers 5
University of Washington
Co-authored papers 4
Columbia University Irving Medical Center
Co-authored papers 4
University of Toronto
Co-authored papers 4
Center for Advanced Biotechnology and Medicine, Rutgers University
Co-authored papers 4
Waksman Institute, Rutgers University
Co-authored papers 4
Yale University
Co-authored papers 3
Center for Structural Biology of Infectious Diseases, University of Chicago
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University of Toronto
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