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Author Details

Alasdair Ivens
University of Washington School of Medicine
1987
174
55
Christopher Churas (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37246647Trypanosome RNA helicase KREH2 differentially controls non-canonical editing and putative repressive structure via a novel proposed 'bifunctional' gRNA in mRNA A6.Nucleic Acids Res2023
37616070A systematic analysis of the human immune response to Plasmodium vivax.J Clin Invest2023
35288654Population genomics of Escherichia coli in livestock-keeping households across a rapidly developing urban landscape.Nat Microbiol2022
34627407Equine grass sickness (a multiple systems neuropathy) is associated with alterations in the gastrointestinal mycobiome.Anim Microbiome2021
33648633Mapping immune variation and <i>var</i> gene switching in naive hosts infected with <i>Plasmodium falciparum</i>.Elife2021
33785633Metabolomics Reveal Potential Natural Substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium.mBio2021
33752799Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria.Elife2021
32487753Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump.mBio2020
32796064Identification of a Functional Small Noncoding RNA of African Swine Fever Virus.J Virol2020
32873716Site-specific and substrate-specific control of accurate mRNA editing by a helicase complex in trypanosomes.RNA2020
32117307The Methyl-CpG-Binding Protein Mbd2 Regulates Susceptibility to Experimental Colitis via Control of CD11c<sup>+</sup> Cells and Colonic Epithelium.Front Immunol2020
32242065The gut microbiome but not the resistome is associated with urogenital schistosomiasis in preschool-aged children.Commun Biol2020
32499763Epidemiology and Phylogenetic Analysis of Viral Respiratory Infections in Vietnam.Front Microbiol2020
30936493The lung environment controls alveolar macrophage metabolism and responsiveness in type 2 inflammation.Nat Immunol2019
31815932Helminth-induced Th2 cell dysfunction is distinct from exhaustion and is maintained in the absence of antigen.PLoS Negl Trop Dis2019
31665448Assembly and annotation of the mitochondrial minicircle genome of a differentiation-competent strain of Trypanosoma brucei.Nucleic Acids Res2019
31636179Developmental competence and antigen switch frequency can be uncoupled in <i>Trypanosoma brucei</i>.Proc Natl Acad Sci U S A2019
31770367Comparative analysis of small RNAs released by the filarial nematode Litomosoides sigmodontis in vitro and in vivo.PLoS Negl Trop Dis2019
31708913Macrophage Migration Inhibitory Factor (MIF) Is Essential for Type 2 Effector Cell Immunity to an Intestinal Helminth Parasite.Front Immunol2019
31506353Intracellular redox potential is correlated with miRNA expression in MCF7 cells under hypoxic conditions.Proc Natl Acad Sci U S A2019
309841801,25-Dihydroxyvitamin D<sub>3</sub> Restrains CD4<sup>+</sup> T Cell Priming Ability of CD11c<sup>+</sup> Dendritic Cells by Upregulating Expression of CD31.Front Immunol2019
29510118TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus.Int J Parasitol2018
29940034Non-linear hierarchy of the quorum sensing signalling pathway in bloodstream form African trypanosomes.PLoS Pathog2018
29898398Inhibition of Microprocessor Function during the Activation of the Type I Interferon Response.Cell Rep2018
30542349Dynamics of Colon Monocyte and Macrophage Activation During Colitis.Front Immunol2018
30307943A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development.PLoS Negl Trop Dis2018
29449965Genetic diversity and cross-species transmission of kobuviruses in Vietnam.Virus Evol2018
29691332Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of <i>Klebsiella pneumoniae</i> Carbapenemase-Carrying Plasmids.mBio2018
28871083Interspecies quorum sensing in co-infections can manipulate trypanosome transmission potential.Nat Microbiol2017
28334017Genome-wide RNAi selection identifies a regulator of transmission stage-enriched gene families and cell-type differentiation in Trypanosoma brucei.PLoS Pathog2017
28503175Heterogeneity of Phenotype and Function Reflects the Multistage Development of T Follicular Helper Cells.Front Immunol2017
29170498A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.Nat Commun2017
29045903HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33.Immunity2017
28903536An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream Revealed through Genome and Transcriptome Analysis of the Ubiquitous Bovine Parasite Trypanosoma (Megatrypanum) theileri.Genome Biol Evol2017
28720734Lack of AcrB Efflux Function Confers Loss of Virulence on <i>Salmonella enterica</i> Serovar Typhimurium.mBio2017
27098483Genomic variation in two gametocyte non-producing Plasmodium falciparum clonal lines.Malar J2016
27879336Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology.mBio2016
27329755Erratum for Richmond et al., The Acinetobacter baumannii Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation, and Virulence in a Strain-Specific Manner.mBio2016
27094331The Acinetobacter baumannii Two-Component System AdeRS Regulates Genes Required for Multidrug Efflux, Biofilm Formation, and Virulence in a Strain-Specific Manner.mBio2016
26914027Small RNA Profiling in Dengue Virus 2-Infected Aedes Mosquito Cells Reveals Viral piRNAs and Novel Host miRNAs.PLoS Negl Trop Dis2016
25568942Genome and phylogenetic analyses of Trypanosoma evansi reveal extensive similarity to T. brucei and multiple independent origins for dyskinetoplasty.PLoS Negl Trop Dis2015
26490107Erratum: Exosomes secreted by nematode parasites transfer small RNAs to mammalian cells and modulate innate immunity.Nat Commun2015
26642852Hif-1α and Hif-2α synergize to suppress AML development but are dispensable for disease maintenance.J Exp Med2015
26443722Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni.J Extracell Vesicles2015
26161560Quantitative Analysis of MicroRNAs in Vaccinia virus Infection Reveals Diversity in Their Susceptibility to Modification and Suppression.PLoS One2015
26114287Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children.PLoS Negl Trop Dis2015
25908537A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells.Nat Commun2015
25899567Modulation of dendritic cell alternative activation and function by the vitamin A metabolite retinoic acid.Int Immunol2015
25873624NMD3 regulates both mRNA and rRNA nuclear export in African trypanosomes via an XPOI-linked pathway.Nucleic Acids Res2015
25623184Extracellular Onchocerca-derived small RNAs in host nodules and blood.Parasit Vectors2015
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Collaborators

Matthew Berriman
Wellcome Sanger Institute
Co-authored papers 16
Bart Barrell
Wellcome Trust Sanger Institute
Co-authored papers 11
Peter J Myler
University of Guelph
Co-authored papers 9
Kenneth Stuart
Seattle Children's Research Institute
Co-authored papers 9
Martin Aslett
The Wellcome Trust Sanger Institute
Co-authored papers 8
Christiane Hertz-Fowler
Institute of Integrative Biology, University of Liverpool
Co-authored papers 7
Jenefer M Blackwell
Co-authored papers 7
Robert Williamson
Murdoch Children's Research Institute
Co-authored papers 7
Neil Hall
Earlham Institute
Co-authored papers 6
Valerie Wood
University of Cambridge
Co-authored papers 4
Steven L Salzberg
Center for Computational Biology, Johns Hopkins University
Co-authored papers 4
Elodie Ghedin
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 4
Owen White
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 4
Lee Murphy
Edinburgh Clinical Research Facility, University of Edinburgh
Co-authored papers 4
Peter Ghazal
UK System Immunity Research Institute, Cardiff University
Co-authored papers 3
Arnab Pain
King Abdullah University of Science and Technology
Co-authored papers 3
Chris I Newbold
Wellcome Trust Sanger Institute
Co-authored papers 3
Mark C Field
University of Dundee
Co-authored papers 3
Elizabeth A Worthey
Heersink School of Medicine, The University of Alabama at Birmingham
Co-authored papers 3
Claire M Fraser
Institute for Genome Sciences, University of Maryland School of Medicine
Co-authored papers 3
Jeremy Peterson
The Institute for Genomic Research, 9712 Medical Center Drive
Co-authored papers 3
Jennifer R Wortman
Broad Institute of MIT and Harvard
Co-authored papers 3
Brian J Haas
Broad Institute of MIT and Harvard
Co-authored papers 3
Carlo V Bruschi
Co-authored papers 2
Judith E Allen
Lydia Becker Institute for Immunology & Infection, University of Manchester
Co-authored papers 2
Samuel V Angiuoli
Personal Genome Diagnostics Inc.
Co-authored papers 2
Tom C Freeman
The Roslin Institute, University of Edinburgh
Co-authored papers 2
Taane G Clark
Co-authored papers 2
Kim Rutherford
University of Cambridge
Co-authored papers 2
David C Schwartz
University of Wisconsin-Madison
Co-authored papers 2
Release 1.2