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Author Details

Jeremy Clark
Norwich Medical School, University of East Anglia
1989
80
40
PMIDPaper TitleJournal TitlePublished Year
36765747Gene-Transcript Expression in Urine Supernatant and Urine Cell-Sediment Are Different but Equally Useful for Detecting Prostate Cancer.Cancers (Basel)2023
36661662Combining Molecular Subtypes with Multivariable Clinical Models Has the Potential to Improve Prediction of Treatment Outcomes in Prostate Cancer at Diagnosis.Curr Oncol2022
35454901A Model to Detect Significant Prostate Cancer Integrating Urinary Peptide and Extracellular Vesicle RNA Data.Cancers (Basel)2022
35450835Microbiomes of Urine and the Prostate Are Linked to Human Prostate Cancer Risk Groups.Eur Urol Oncol2022
33925381Integration of Urinary EN2 Protein & Cell-Free RNA Data in the Development of a Multivariable Risk Model for the Detection of Prostate Cancer Prior to Biopsy.Cancers (Basel)2021
32203215A novel stratification framework for predicting outcome in patients with prostate cancer.Br J Cancer2020
31779479Methodology for the at-home collection of urine samples for prostate cancer detection.Biotechniques2020
32153047Development of a multivariable risk model integrating urinary cell DNA methylation and cell-free RNA data for the detection of significant prostate cancer.Prostate2020
31106513A four-group urine risk classifier for predicting outcomes in patients with prostate cancer.BJU Int2019
30801051epiCaPture: A Urine DNA Methylation Test for Early Detection of Aggressive Prostate Cancer.JCO Precis Oncol2019
28753852DESNT: A Poor Prognosis Category of Human Prostate Cancer.Eur Urol Focus2018
30470249A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prostate cancer.Clin Epigenetics2018
28945760Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data.PLoS Genet2017
28292578Corrigendum to "Integration of Copy Number and Transcriptomics Provides Risk Stratification in Prostate Cancer: A Discovery and Validation Cohort Study" [EBioMedicine 2 (9) (2015) 1133-1144].EBioMedicine2017
28419548Detection of prostate cancer-specific transcripts in extracellular vesicles isolated from post-DRE urine.Prostate2017
26455355Prostate Single Nucleotide Polymorphism Provides a Crucial Clue to Cancer Aggression in Active Surveillance Patients.Eur Urol2016
25586381Mutation detection in formalin-fixed prostate cancer biopsies taken at the time of diagnosis using next-generation DNA sequencing.J Clin Pathol2015
26501111Integration of copy number and transcriptomics provides risk stratification in prostate cancer: A discovery and validation cohort study.EBioMedicine2015
26162314Building Data-Driven Pathways From Routinely Collected Hospital Data: A Case Study on Prostate Cancer.JMIR Med Inform2015
26018901Corrigendum: analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.Nat Genet2015
25664317Biomarker and translational prostate cancer research.Biomed Res Int2015
25730763Analysis of the genetic phylogeny of multifocal prostate cancer identifies multiple independent clonal expansions in neoplastic and morphologically normal prostate tissue.Nat Genet2015
24481405Focal amplification of the androgen receptor gene in hormone-naive human prostate cancer.Br J Cancer2014
23774836The present and future of prostate cancer urine biomarkers.Int J Mol Sci2013
23695019Prognostic value of PTEN loss in men with conservatively managed localised prostate cancer.Br J Cancer2013
22460813Novel, gross chromosomal alterations involving PTEN cooperate with allelic loss in prostate cancer.Mod Pathol2012
23059046Prognostic value of blood mRNA expression signatures in castration-resistant prostate cancer: a prospective, two-stage study.Lancet Oncol2012
23144797Multi-purpose utility of circulating plasma DNA testing in patients with advanced cancers.PLoS One2012
22833462Identification of frequent BRAF copy number gain and alterations of RAF genes in Chinese prostate cancer.Genes Chromosomes Cancer2012
21383285Phase I trial of a selective c-MET inhibitor ARQ 197 incorporating proof of mechanism pharmacodynamic studies.J Clin Oncol2011
20104229Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer.Br J Cancer2010
20177423The identification of chromosomal translocation, t(4;6)(q22;q15), in prostate cancer.Prostate Cancer Prostatic Dis2010
20145164Studies of TMPRSS2-ERG gene fusions in diagnostic trans-rectal prostate biopsies.Clin Cancer Res2010
19040532Integration of ERG gene mapping and gene-expression profiling identifies distinct categories of human prostate cancer.BJU Int2009
19657377ETS gene fusions in prostate cancer.Nat Rev Urol2009
19707199Hsp-27 expression at diagnosis predicts poor clinical outcome in prostate cancer independent of ETS-gene rearrangement.Br J Cancer2009
19638540An improved method for constructing tissue microarrays from prostate needle biopsy specimens.J Clin Pathol2009
19544327A novel, spontaneously immortalized, human prostate cancer cell line, Bob, offers a unique model for pre-clinical prostate cancer studies.Prostate2009
17637754Duplication of the fusion of TMPRSS2 to ERG sequences identifies fatal human prostate cancer.Oncogene2008
18594527Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer.Br J Cancer2008
18645193Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven.J Clin Oncol2008
18274524Fluorescence and chromogenic in situ hybridization to detect genetic aberrations in formalin-fixed paraffin embedded material, including tissue microarrays.Nat Protoc2008
17922029Complex patterns of ETS gene alteration arise during cancer development in the human prostate.Oncogene2008
18165275Detection of TMPRSS2-ERG translocations in human prostate cancer by expression profiling using GeneChip Human Exon 1.0 ST arrays.J Mol Diagn2008
17244020A conditionally immortalized cell line model for the study of human prostatic epithelial cell differentiation.Differentiation2007
17043636Diversity of TMPRSS2-ERG fusion transcripts in the human prostate.Oncogene2007
16546166Candidate tumor suppressor LUCA-15/RBM5/H37 modulates expression of apoptosis and cell cycle genes.Exp Cell Res2006
16849266Identification of prognostic signatures in breast cancer microarray data using Bayesian techniques.J R Soc Interface2006
16938365Nuclear overexpression of the E2F3 transcription factor in human lung cancer.Lung Cancer2006
15583692Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer.Br J Cancer2005
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Collaborators

Norwich Medical School, University of East Anglia
Co-authored papers 67
University of Washington, USA Institute for Stem Cell and Regenerative Medicine
Co-authored papers 24
The Institute of Cancer Research
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The Institute for Cancer Research
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University Hospitals Birmingham NHS Foundation Trust
Co-authored papers 15
The Institute of Cancer Research
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The Institute of Cancer Research
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Barts Cancer Institute, Queen Mary University of London
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Seattle Children's Research Institute (K Liljenquist
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The Institute of Cancer Research
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Institute of Cancer Research
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Institute of Cancer Research
Co-authored papers 8
The Royal Marsden NHS Foundation Trust
Co-authored papers 7
University of St Andrews
Co-authored papers 7
University of Cambridge
Co-authored papers 7
University College London
Co-authored papers 7
University of Oxford, John Radcliffe Hospital
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Cambridge University Hospitals National Health Service Foundation Trust
Co-authored papers 6
Barts Cancer Institute, Queen Mary University of London
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University of Cambridge
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The Institute of Cancer Research
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Cambridge University Hospitals NHS Foundation Trust
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University College London
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The Royal Marsden Hospital NHS Foundation Trust
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Queen's University Belfast
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Memorial Sloan Kettering Cancer Center
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Manchester Cancer Research Centre, University of Manchester
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The Institute of Cancer Research
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Wellcome Sanger Institute
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