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Author Details

Davide Ruggero
University of California San Francisco
1996
87
48
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36264168N-myc-Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma.Cancer Res2023
37816716Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer.Nat Commun2023
37495694Evolutionarily divergent mTOR remodels translatome for tissue regeneration.Nature2023
37306301Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs <i>Rps27</i> and <i>Rps27l</i> in vertebrates.Elife2023
35315941Protein synthesis control in cancer: selectivity and therapeutic targeting.EMBO J2022
35597236Localization of a TORC1-eIF4F translation complex during CD8<sup>+</sup> T cell activation drives divergent cell fate.Mol Cell2022
36563140Regulation of eIF4E guides a unique translational program to control erythroid maturation.Sci Adv2022
35868253A tRF nucleator for Nucleolin in cancer metastasis.Mol Cell2022
36123449Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3.Nat Chem2022
33246980Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies.J Nucl Med2021
33619378The major cap-binding protein eIF4E regulates lipid homeostasis and diet-induced obesity.Nat Metab2021
34559986ERα is an RNA-binding protein sustaining tumor cell survival and drug resistance.Cell2021
34019295Examining Myc-Dependent Translation Changes in Cellular Homeostasis and Cancer.Methods Mol Biol2021
34214436Releasing the brake on protein synthesis in hematopoietic stem cells.Cell Stem Cell2021
34192540Revealing molecular pathways for cancer cell fitness through a genetic screen of the cancer translatome.Cell Rep2021
34278258Reduced eIF4E function impairs B-cell leukemia without altering normal B-lymphocyte function.iScience2021
32353859A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.Nature2020
31792071Profiling the Surfaceome Identifies Therapeutic Targets for Cells with Hyperactive mTORC1 Signaling.Mol Cell Proteomics2020
32813112An Analysis of Isoclonal Antibody Formats Suggests a Role for Measuring PD-L1 with Low Molecular Weight PET Radiotracers.Mol Imaging Biol2020
30530594The mTORC1/4E-BP/eIF4E Axis Promotes Antibody Class Switching in B Lymphocytes.J Immunol2019
29959193Translational Control in Cancer.Cold Spring Harb Perspect Biol2019
31300274Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay.Mol Cell2019
31263264ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.Nat Cell Biol2019
31316187Author Correction: ATF4 couples MYC-dependent translational activity to bioenergetic demands during tumour progression.Nat Cell Biol2019
31478838A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS.Elife2019
31041393Measuring Dynamic Changes in the Labile Iron Pool in Vivo with a Reactivity-Based Probe for Positron Emission Tomography.ACS Cent Sci2019
30827827A Legionella pneumophila Kinase Phosphorylates the Hsp70 Chaperone Family to Inhibit Eukaryotic Protein Synthesis.Cell Host Microbe2019
30643286Translation control of the immune checkpoint in cancer and its therapeutic targeting.Nat Med2019
29316436Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase.Cancer Cell2018
30028999A Translation Tuning HuDdle for Neurons.Mol Cell2018
29967029A wobbly road to drug resistance in melanoma: tRNA-modifying enzymes in translation reprogramming.EMBO J2018
29720449Development of a stress response therapy targeting aggressive prostate cancer.Sci Transl Med2018
29467287Revealing nascent proteomics in signaling pathways and cell differentiation.Proc Natl Acad Sci U S A2018
29230015A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival.Nat Cell Biol2018
28007777Noninvasive Measurement of mTORC1 Signaling with <sup>89</sup>Zr-Transferrin.Clin Cancer Res2017
28436470New frontiers in translational control of the cancer genome.Nat Rev Cancer2017
28641761Editorial overview: Cell regulation: 1000 Flavors including chocolate and chili peppers.Curr Opin Cell Biol2017
27112207New frontiers in translational control of the cancer genome.Nat Rev Cancer2016
27245614The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes.Sci Signal2016
25363811Small RNAs with big implications: new insights into H/ACA snoRNA function and their role in human disease.Wiley Interdiscip Rev RNA2015
26577921Cell type-specific abundance of 4EBP1 primes prostate cancer sensitivity or resistance to PI3K pathway inhibitors.Sci Signal2015
26095252Differential Requirements for eIF4E Dose in Normal Development and Cancer.Cell2015
25977330Enhanced MET Translation and Signaling Sustains K-Ras-Driven Proliferation under Anchorage-Independent Growth Conditions.Cancer Res2015
25797255YB-1 and MTA1 protein levels and not DNA or mRNA alterations predict for prostate cancer recurrence.Oncotarget2015
25593033Targeting the eIF4F translation initiation complex: a critical nexus for cancer development.Cancer Res2015
24213167Parallel measurement of dynamic changes in translation rates in single cells.Nat Methods2014
25237201Marrow failure: a window into ribosome biology.Blood2014
24855946Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer.Cell2014
24702992Tailor made protein synthesis for HSCs.Cell Stem Cell2014
22767671Translational control in cancer etiology.Cold Spring Harb Perspect Biol2013
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Collaborators

Kevan M Shokat
University of California San Francisco
Co-authored papers 7
Duygu Kuzuo??lu-??zt??rk
University of California san francisco
Co-authored papers 6
Alma L Burlingame
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 5
John Alan Diehl
Case Western Reserve University School of Medicine
Co-authored papers 4
Juan A Oses-Prieto
Co-authored papers 4
David A Fruman
Co-authored papers 3
Youngho Seo
University of California san francisco
Co-authored papers 3
John D Gordan
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 2
Shaeri Mukherjee
G.W. Hooper Foundation, University of California at San Francisco
Co-authored papers 2
Adam B Olshen
12224University of California san francisco
Co-authored papers 2
Adam R Renslo
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Shizhong Dai
University of California san francisco
Co-authored papers 2
Charles S Craik
Department of Pharmaceutical Chemistry, University of California san francisco
Co-authored papers 2
Barry S Taylor
Memorial Sloan Kettering Cancer Center
Co-authored papers 2
Jack Taunton
University of California san francisco
Co-authored papers 2
Andrew V Kossenkov
The Wistar Institute
Co-authored papers 2
Jason E Gestwicki
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 2
Scott A Oakes
Pritzker School of Medicine, University of Chicago
Co-authored papers 1
Melanie J Bennett
Quantitative Biosciences Institute (QBI), University of California San Francisco
Co-authored papers 1
Djoshkun Shengjuler
Institut Pasteur
Co-authored papers 1
Srivats Venkataramanan
Management and Science University
Co-authored papers 1
Andrei Goga
University of California San Francisco
Co-authored papers 1
Hannes Braberg
University of California San Francisco
Co-authored papers 1
Yiming Cai
Institute of Mental Health and Woodbridge Hospital
Co-authored papers 1
Alan D Frankel
University of California san francisco
Co-authored papers 1
Andrej Sali (CM4AI)
University of California San Francisco
Co-authored papers 1
Eric Verdin
Buck Institute for Research on Aging
Co-authored papers 1
Danica Galoni?? Fujimori
University of California San Francisco
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Matthew B Rettig
David Geffen School of Medicine, University of California los angeles
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Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences
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Release 1.2